{"created":"2024-10-08T01:47:06.567002+00:00","id":2020637,"links":{},"metadata":{"_buckets":{"deposit":"f070afdd-0df0-4ee5-ad6e-9d068b320371"},"_deposit":{"created_by":8,"id":"2020637","owner":"8","owners":[8],"pid":{"revision_id":0,"type":"depid","value":"2020637"},"status":"published"},"_oai":{"id":"oai:u-ryukyu.repo.nii.ac.jp:02020637","sets":["1642838163960:1642838198944:1642838199408:1728346061696","1642838403551:1642838412624"]},"author_link":[],"control_number":"2020637","item_1617186331708":{"attribute_name":"Title","attribute_value_mlt":[{"subitem_title":"The correlation between HTLV-1 and Whipple's disease in a Japanese population: A case series","subitem_title_language":"en"}]},"item_1617186419668":{"attribute_name":"Creator","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Graduate school of Medicine, University of the Ryukyus","affiliationNameLang":"en"},{"affiliationName":"琉球大学大学院医学研究科","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"Furugen, Tomonori","creatorNameLang":"en"}]},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"University of the Ryukyus Hospital","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Kinjo, Tetsu","creatorNameLang":"en"}]},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"University of the Ryukyus Hospital","affiliationNameLang":"en"}]}],"creatorNames":[{"creatorName":"Hokama, Akira","creatorNameLang":"en"}]},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Graduate school of Medicine, University of the Ryukyus","affiliationNameLang":"en"},{"affiliationName":"琉球大学大学院医学研究科","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"Furukawa, Kojiro","creatorNameLang":"en"}]},{"creatorAffiliations":[{"affiliationNames":[{"affiliationName":"Graduate School of Medicine, Nagoya University","affiliationNameLang":"en"},{"affiliationName":"名古屋大学大学院医学系研究科","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"Karube, Kennosuke","creatorNameLang":"en"}]}]},"item_1617186476635":{"attribute_name":"アクセス権","attribute_value_mlt":[{"subitem_access_right":"open access","subitem_access_right_uri":"http://purl.org/coar/access_right/c_abf2"}]},"item_1617186499011":{"attribute_name":"Rights","attribute_value_mlt":[{"subitem_rights":"琉球医学会","subitem_rights_language":"ja"},{"subitem_rights":"Ryukyu Medical Association","subitem_rights_language":"en"}]},"item_1617186609386":{"attribute_name":"Subject","attribute_value_mlt":[{"subitem_subject":"Whippleʼs disease","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"HTLV-1","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"immunosuppression","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"proviral load","subitem_subject_language":"en","subitem_subject_scheme":"Other"},{"subitem_subject":"adult T-cell leukemia / lymphoma","subitem_subject_language":"en","subitem_subject_scheme":"Other"}]},"item_1617186626617":{"attribute_name":"Description","attribute_value_mlt":[{"subitem_description":"Purpose: Whippleʼs disease (WD) is a rare systemic disease caused by Tropheryma whipplei. It is predominantly diagnosed in middle-aged Caucasian men, and its association with immunosuppression and human leukocyte antigen (HLA)-B27 has been discussed; however, these studies are limited to western countries. Herein, we analyzed five WD cases and eight previously described WD cases in the Japanese population.\nResults: None of the patients were under immunosuppressive treatment or HLA-B27-positive. In 10/13 cases checking anti-HTLV-1 antibody, 6/10 (60%) cases were carriers of human T-cell leukemia virus type 1 (HTLV-1). All patients were treated with antibiotics, and their symptoms diminished promptly. The prognosis for these cases was excellent, and one patient developed the smoldering type adult T-cell leukemia/lymphoma, but no progression to aggressive type adult T-cell leukemia/lymphoma was observed.\nConclusion: These findings probably support the findings that the immunosuppressive effect of HTLV-1 triggers WD in Japanese patients. It is recommended to evaluate the presence of HTLV-1 antibody in the blood of WD patients in HTLV-1 endemic areas for the clarification of the accurate pathogenesis and appropriate clinical follow-up. Ryukyu Med. J., 42 (1～4) 21～28, 2023","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_1617186643794":{"attribute_name":"Publisher","attribute_value_mlt":[{"subitem_publisher":"琉球医学会","subitem_publisher_language":"ja"},{"subitem_publisher":"Ryukyu Medical Association","subitem_publisher_language":"en"}]},"item_1617186702042":{"attribute_name":"Language","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_1617186920753":{"attribute_name":"Source Identifier","attribute_value_mlt":[{"subitem_source_identifier":"1346-888X","subitem_source_identifier_type":"EISSN"},{"subitem_source_identifier":"AN10369445","subitem_source_identifier_type":"NCID"}]},"item_1617186941041":{"attribute_name":"Source Title","attribute_value_mlt":[{"subitem_source_title":"琉球医学会誌 = Ryukyu Medical Journal","subitem_source_title_language":"ja"}]},"item_1617187056579":{"attribute_name":"bibliographic_information","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2023","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1-4","bibliographicPageEnd":"28","bibliographicPageStart":"21","bibliographicVolumeNumber":"42"}]},"item_1617258105262":{"attribute_name":"item_1617258105262","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_1617265215918":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_1617605131499":{"attribute_name":"File","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_access","date":[{"dateType":"Available","dateValue":"2024-10-08"}],"filename":"F_No42p21.pdf","filesize":[{"value":"1.2 MB"}],"mimetype":"application/pdf","url":{"objectType":"fulltext","url":"https://u-ryukyu.repo.nii.ac.jp/record/2020637/files/F_No42p21.pdf"},"version_id":"6b4e66b9-30fc-4beb-a30e-5e1735fd2616"}]},"item_title":"The correlation between HTLV-1 and Whipple's disease in a Japanese population: A case series","item_type_id":"59","owner":"8","path":["1728346061696","1642838412624"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2024-10-08"},"publish_date":"2024-10-08","publish_status":"0","recid":"2020637","relation_version_is_last":true,"title":["The correlation between HTLV-1 and Whipple's disease in a Japanese population: A case series"],"weko_creator_id":"8","weko_shared_id":-1},"updated":"2024-10-10T00:48:00.534551+00:00"}