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  1. 学位論文
  2. 博士論文
  3. 医学研究科
  1. 部局別インデックス
  2. 医学研究科

海馬記憶回路網のパターン分離における小脳の役割

http://hdl.handle.net/20.500.12000/33565
http://hdl.handle.net/20.500.12000/33565
4f521d8e-6865-4651-beaa-7e4d704ad856
名前 / ファイル ライセンス アクション
iken442text.pdf iken442text.pdf
iken442review.pdf iken442review.pdf
iken442abstract.pdf iken442abstract.pdf
Item type デフォルトアイテムタイプ(フル)(1)
公開日 2016-04-15
タイトル
タイトル 海馬記憶回路網のパターン分離における小脳の役割
言語 ja
作成者 城間, 綾乃

× 城間, 綾乃

ja 城間, 綾乃

Shiroma, Ayano

× Shiroma, Ayano

en Shiroma, Ayano

アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
主題
言語 en
主題Scheme Other
主題 Posterior lateral cerebellum
言語 en
主題Scheme Other
主題 Cognitive function
言語 en
主題Scheme Other
主題 Brain tumor
言語 en
主題Scheme Other
主題 Memory
言語 en
主題Scheme Other
主題 Hippocampus
言語 en
主題Scheme Other
主題 fMRI
内容記述
内容記述タイプ Other
内容記述 The cerebellum is a crucial structure for cognitive function as well as motor control. Benign brain tumors such as schwannomas, meningiomas, and epidermoids tend to occur in the cerebellopontine angle cisterns and may cause compression of the posterior lateral cerebellum near the superior posterior fissure, where the eloquent area for cognitive function was recently identified. The present study examined cognitive impairment in patients with benign cerebellar tumors before and after surgical intervention in order to clarify the functional implications of this region in humans. Patients with cerebellar tumors showed deficits in psychomotor speed and working memory compared with healthy controls. Moreover, these impairments were more pronounced in patients with right cerebellar tumors. Functional magnetic resonance imaging during performance of a lure task also demonstrated that cerebellar tumors affected pattern separation or the ability to distinguish similar experiences of episodic memory or events with discrete, non-overlapping representations, which is one of the important cognitive functions related to the hippocampus. The present findings indicate that compression of the human posterior lateral cerebellum affects hippocampal memory function.
内容記述タイプ Other
内容記述 学位論文
出版者
言語 ja
出版者 琉球大学
言語
言語 eng
資源タイプ
資源タイプ doctoral thesis
資源タイプ識別子 http://purl.org/coar/resource_type/c_db06
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
識別子
識別子 http://hdl.handle.net/20.500.12000/33565
識別子タイプ HDL
関連情報
関連識別子
識別子タイプ DOI
関連識別子 10.1007/s12311-015-0726-0
関連識別子
識別子タイプ PMID
関連識別子 26439485
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 1473-4222
収録物名
言語 en
収録物名 The Cerebellum
書誌情報
p. 1-18
学位授与番号
学位授与番号 甲第442号
学位名
学位名 博士(医学)
言語 ja
学位授与年月日
学位授与年月日 2015-12-18
学位授与機関
学位授与機関識別子
学位授与機関識別子 18001
学位授与機関識別子Scheme kakenhi
学位授与機関名
学位授与機関名 琉球大学
言語 ja
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