Item type |
デフォルトアイテムタイプ(フル)(1) |
公開日 |
2021-11-17 |
タイトル |
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タイトル |
Whole-Genome Sequencing of a 900-Year-Old Human Skeleton Supports Two Past Migration Events from the Russian Far East to Northern Japan |
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言語 |
en |
作成者 |
Sato, Takehiro
Adachi, Noboru
Kimura, Ryosuke
Hosomichi, Kazuyoshi
Yoneda, Minoru
Oota, Hiroki
Tajima, Atsushi
Toyoda, Atsushi
Kanazawa-Kiriyama, Hideaki
Matsumae, Hiromi
Koganebuchi, Kae
Shimizu, K Kentaro
Shinoda, Ken-ichi
Hanihara, Tsunehiko
Weber, Andrzej
Kato, Hirofumi
Ishida, Hajime
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アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
権利情報 |
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言語 |
ja |
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権利情報 |
© The Author(s) 2021 |
権利情報 |
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言語 |
en |
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権利情報 |
Creative Commons Attribution 4.0 |
権利情報 |
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言語 |
en |
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権利情報Resource |
https://creativecommons.org/licenses/by/4.0/ |
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権利情報 |
https://creativecommons.org/licenses/by/4.0/ |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
prehistoric Okhotsk people |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
ancient genomics |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
next-generation sequencing |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
population history |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
admixture dating |
内容記述 |
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内容記述タイプ |
Other |
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内容記述 |
Recent studies on paleogenomics have reported some Paleolithic and Neolithic genomes that have provided new insights into the human population history in East and Northeast Asia. However, there remain some cases where more recent migration events need to be examined to elucidate the detailed formation process of local populations. Although the area around northern Japan is one of the regions archaeologically suggested to have been affected by migration waves after the Neolithic period, the genetic source of these migrations are still unclear. Thus, genomic data from such past migrant populations would be highly informative to clarify the detailed formation process of local populations in this region. Here, we report the genome sequence of a 900-year-old adult female (NAT002) belonging to the prehistoric Okhotsk people, who have been considered to be the past migrants to northern Japan after the Neolithic period. We found a close relationship between NAT002 and modern Lower Amur populations and past admixture events between the Amur, Jomon, and Kamchatka ancestries. The admixture dating suggested migration of Amur-related ancestry at approximately 1,600 BP, which is compatible with the archaeological evidence regarding the settlement of the Okhotsk people. Our results also imply migration of Kamchatka-related ancestry at approximately 2,000 BP. In addition, human leukocyte antigen (HLA) typing detected the HLA-B*40 allele, which is reported to increase the risk of arthritis, suggesting the genetic vulnerability of NAT002 to hyperostosis, which was observed around her chest clavicle. |
内容記述 |
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内容記述タイプ |
Other |
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内容記述 |
論文 |
出版者 |
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出版者 |
Oxford University Press |
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言語 |
en |
言語 |
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言語 |
eng |
資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
出版タイプ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
識別子 |
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識別子 |
http://hdl.handle.net/20.500.12000/50052 |
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識別子タイプ |
HDL |
関連情報 |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1093/gbe/evab192 |
関連情報 |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1093/gbe/evab192 |
収録物識別子 |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
1759-6653 |
収録物名 |
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収録物名 |
Genome Biology and Evolution |
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言語 |
en |
書誌情報 |
巻 13,
号 9,
発行日 2021-08-19
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