| Item type |
デフォルトアイテムタイプ（フル）(1) |
| 公開日 |
2020-10-09 |
| タイトル |
|
|
タイトル |
Sarcoidosis of mediastinal lymph nodes mimicking distant metastasis of oral squamous cell carcinoma : a case report and review of literature |
|
言語 |
en |
| 作成者 |
Maruyama, Tessho
Saio, Masanao
Arasaki, Akira
Nakasone, Toshiyuki
Teruya, Takao
Haranaga, Shusaku
Nimura, Fumikazu
Kawano, Toshihiro
Matayoshi, Akira
Yoshimi, Naoki
Kuniyoshi, Yukio
Fujita, Jiro
Nishihara, Kazuhide
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利情報 |
|
|
言語 |
en |
|
権利情報 |
Creative Commons Attribution Noncommercial |
| 権利情報 |
|
|
言語 |
en |
|
権利情報Resource |
https://creativecommons.org/licenses/by-nc/4.0/ |
|
権利情報 |
https://creativecommons.org/licenses/by-nc/4.0/ |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Sarcoidosis |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
subsequent cancer |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
lymphadenopathy |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
head and neck cancer |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
oral cavity |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
distant metastasis |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
biopsy |
| 内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
Sarcoidosis is a systemic, chronic inflammatory disease with unknown cause and is characterized by formation of epithelioid granulomas in various organs, mainly the lungs and lymphatic system as mediastinal lymph nodes (LNs). Lymphadenopathy is common in sarcoidosis. Subsequent cancer also tends to occur in patients with the disease, and the most frequent is lymphoma and cancer of the lung. Head and neck cancer is uncommon but possible. We report a 70-year-old woman with squamous cell carcinoma (SCC) of the mandibular gingiva concomitant with mediastinal multiple lymphadenopathy, and a medical history of chronic sarcoidosis. Mediastinal LNs showed increased uptake of 2-[18F]-fluoro-2-deoxy-d-glucose (FDG) with positron emission tomography (PET). Subsequent to lymphadenectomy, the histological diagnosis was lymphadenopathy caused by sarcoidosis. Next, we performed wide local excision of the gingival tumor. During follow-up, a pulmonary lesion was detected by computed tomography at 3 years and 11 months after surgery, and diagnosed as pulmonary sarcoidosis, which had been stable without treatment until now. After follow-up of 5 years, the patient was alive without signs of local recurrence or metastasis. The combination of oral SCC and sarcoidosis of the mediastinal LNs in a sarcoidosis patient has not been previously reported. FDG-PET was not able to distinguish LN metastasis from lymphadenopathy caused by sarcoidosis. In our case, her chronic inflammatory condition with sarcoidosis as well as ill-fitting dentures could have increased the risk of oral cancer. We suggest that clinicians should carefully check for the development of subsequent oral cancer in patients with a past history of sarcoidosis. To avoid inaccurate staging and incorrect therapy, LN biopsy should be promptly performed following a diagnosis of cancer and multiple lymphadenopathies in patients with a history of sarcoidosis. Lymphadenopathy with sarcoidosis patients have malignant potential, especially those who develop subsequent cancer. Misdiagnosis of LN malignancy and sarcoidosis may lead to unnecessary adjuvant therapy or worse prognosis. |
| 内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
論文 |
| 出版者 |
|
|
出版者 |
e-Century Publishing |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 識別子 |
|
|
識別子 |
http://hdl.handle.net/20.500.12000/46925 |
|
識別子タイプ |
HDL |
| 関連情報 |
|
|
|
識別子タイプ |
URI |
|
|
関連識別子 |
http://www.ijcem.com/files/ijcem0059398.pdf |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
1940-5901 |
| 収録物名 |
|
|
収録物名 |
International Journal of Clinical and Experimental Medicine |
|
言語 |
en |
| 書誌情報 |
巻 11,
号 3,
p. 2698-2708,
発行日 2018-03-30
|
ijcem0059398.pdf
