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  1. 学術雑誌論文
  2. その他
  1. 部局別インデックス
  2. 医学部

Sarcoidosis of mediastinal lymph nodes mimicking distant metastasis of oral squamous cell carcinoma : a case report and review of literature

http://hdl.handle.net/20.500.12000/46925
http://hdl.handle.net/20.500.12000/46925
97cc340c-36f2-4bc8-bd19-592a53558aa6
名前 / ファイル ライセンス アクション
ijcem0059398.pdf ijcem0059398.pdf
Item type デフォルトアイテムタイプ(フル)(1)
公開日 2020-10-09
タイトル
タイトル Sarcoidosis of mediastinal lymph nodes mimicking distant metastasis of oral squamous cell carcinoma : a case report and review of literature
言語 en
作成者 Maruyama, Tessho

× Maruyama, Tessho

en Maruyama, Tessho

Saio, Masanao

× Saio, Masanao

en Saio, Masanao

Arasaki, Akira

× Arasaki, Akira

en Arasaki, Akira

Nakasone, Toshiyuki

× Nakasone, Toshiyuki

en Nakasone, Toshiyuki

Teruya, Takao

× Teruya, Takao

en Teruya, Takao

Haranaga, Shusaku

× Haranaga, Shusaku

en Haranaga, Shusaku

Nimura, Fumikazu

× Nimura, Fumikazu

en Nimura, Fumikazu

Kawano, Toshihiro

× Kawano, Toshihiro

en Kawano, Toshihiro

Matayoshi, Akira

× Matayoshi, Akira

en Matayoshi, Akira

Yoshimi, Naoki

× Yoshimi, Naoki

en Yoshimi, Naoki

Kuniyoshi, Yukio

× Kuniyoshi, Yukio

en Kuniyoshi, Yukio

Fujita, Jiro

× Fujita, Jiro

en Fujita, Jiro

Nishihara, Kazuhide

× Nishihara, Kazuhide

en Nishihara, Kazuhide

アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利情報
言語 en
権利情報 Creative Commons Attribution Noncommercial
言語 en
権利情報Resource https://creativecommons.org/licenses/by-nc/4.0/
権利情報 https://creativecommons.org/licenses/by-nc/4.0/
主題
言語 en
主題Scheme Other
主題 Sarcoidosis
言語 en
主題Scheme Other
主題 subsequent cancer
言語 en
主題Scheme Other
主題 lymphadenopathy
言語 en
主題Scheme Other
主題 head and neck cancer
言語 en
主題Scheme Other
主題 oral cavity
言語 en
主題Scheme Other
主題 distant metastasis
言語 en
主題Scheme Other
主題 biopsy
内容記述
内容記述タイプ Other
内容記述 Sarcoidosis is a systemic, chronic inflammatory disease with unknown cause and is characterized by formation of epithelioid granulomas in various organs, mainly the lungs and lymphatic system as mediastinal lymph nodes (LNs). Lymphadenopathy is common in sarcoidosis. Subsequent cancer also tends to occur in patients with the disease, and the most frequent is lymphoma and cancer of the lung. Head and neck cancer is uncommon but possible. We report a 70-year-old woman with squamous cell carcinoma (SCC) of the mandibular gingiva concomitant with mediastinal multiple lymphadenopathy, and a medical history of chronic sarcoidosis. Mediastinal LNs showed increased uptake of 2-[18F]-fluoro-2-deoxy-d-glucose (FDG) with positron emission tomography (PET). Subsequent to lymphadenectomy, the histological diagnosis was lymphadenopathy caused by sarcoidosis. Next, we performed wide local excision of the gingival tumor. During follow-up, a pulmonary lesion was detected by computed tomography at 3 years and 11 months after surgery, and diagnosed as pulmonary sarcoidosis, which had been stable without treatment until now. After follow-up of 5 years, the patient was alive without signs of local recurrence or metastasis. The combination of oral SCC and sarcoidosis of the mediastinal LNs in a sarcoidosis patient has not been previously reported. FDG-PET was not able to distinguish LN metastasis from lymphadenopathy caused by sarcoidosis. In our case, her chronic inflammatory condition with sarcoidosis as well as ill-fitting dentures could have increased the risk of oral cancer. We suggest that clinicians should carefully check for the development of subsequent oral cancer in patients with a past history of sarcoidosis. To avoid inaccurate staging and incorrect therapy, LN biopsy should be promptly performed following a diagnosis of cancer and multiple lymphadenopathies in patients with a history of sarcoidosis. Lymphadenopathy with sarcoidosis patients have malignant potential, especially those who develop subsequent cancer. Misdiagnosis of LN malignancy and sarcoidosis may lead to unnecessary adjuvant therapy or worse prognosis.
内容記述タイプ Other
内容記述 論文
出版者
言語 en
出版者 e-Century Publishing
言語
言語 eng
資源タイプ
資源タイプ journal article
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
識別子
識別子 http://hdl.handle.net/20.500.12000/46925
識別子タイプ HDL
関連情報
関連識別子
識別子タイプ URI
関連識別子 http://www.ijcem.com/files/ijcem0059398.pdf
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 1940-5901
収録物名
言語 en
収録物名 International Journal of Clinical and Experimental Medicine
書誌情報
巻 11, 号 3, p. 2698-2708
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