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  1. 学術雑誌論文
  2. その他
  1. 部局別インデックス
  2. 医学部

The Human SDF1 Gene Polymorphism Is Located on a Mutational Hot Spot that Was Identified by the Hominoid Genome Study

http://hdl.handle.net/20.500.12000/47017
http://hdl.handle.net/20.500.12000/47017
e5fa32a9-0142-46fd-bd7e-11485d4860c4
名前 / ファイル ライセンス アクション
The_Human_SDF1_Gene_Polymorphi.PDF The_Human_SDF1_Gene_Polymorphi.PDF
Item type デフォルトアイテムタイプ(フル)(1)
公開日 2020-10-20
タイトル
タイトル The Human SDF1 Gene Polymorphism Is Located on a Mutational Hot Spot that Was Identified by the Hominoid Genome Study
言語 en
作成者 Kimura, Ryosuke

× Kimura, Ryosuke

en Kimura, Ryosuke

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Ishida, Takafumi

× Ishida, Takafumi

en Ishida, Takafumi

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アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
内容記述
内容記述タイプ Other
内容記述 Nucleotide sequences of a part of the stromal cell-derived factor-1 (SDF-1) gene 3´ untranslated region were studied among hominoids (chimpanzees, gorillas, orangutans and gibbons). An identical sequence to the human SDF1-3´G allele was found in chimpanzees and gibbons, whereas that to the 3´A allele was found in gorillas. Based on the sequence data and the hominoid phylogenetic relation, it was suggested that an adenine nucleotide at nucleotide position (np) 801 in humans and gorillas was independently introduced into each lineage after the specific divergence and an ancestral hominoid sequence of this site (np 799-802) was deduced as CCGG. The present data showing a mutational hot spot on this site suggest the possible presence of multiple origins of the worldwide distribution of the SDF1-3´A allele in humans.
内容記述
内容記述タイプ Other
内容記述 論文
出版者
言語 en
出版者 Wayne State University Press
言語
言語 eng
資源タイプ
資源タイプ journal article
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
識別子
識別子 http://hdl.handle.net/20.500.12000/47017
識別子タイプ HDL
関連情報
識別子タイプ DOI
関連識別子 https://doi.org/10.1353/hub.2001.0084
関連情報
識別子タイプ DOI
関連識別子 https://doi.org/10.1353/hub.2001.0084
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 0018-7143
収録物名
言語 en
収録物名 Human Biology
書誌情報
巻 73, 号 6, p. 891-895, 発行日 2001-12
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