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The Human SDF1 Gene Polymorphism Is Located on a Mutational Hot Spot that Was Identified by the Hominoid Genome Study
http://hdl.handle.net/20.500.12000/47017
http://hdl.handle.net/20.500.12000/47017e5fa32a9-0142-46fd-bd7e-11485d4860c4
名前 / ファイル | ライセンス | アクション |
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Item type | デフォルトアイテムタイプ(フル)(1) | |||||||||
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公開日 | 2020-10-20 | |||||||||
タイトル | ||||||||||
タイトル | The Human SDF1 Gene Polymorphism Is Located on a Mutational Hot Spot that Was Identified by the Hominoid Genome Study | |||||||||
言語 | en | |||||||||
作成者 |
Kimura, Ryosuke
× Kimura, Ryosuke
× Ishida, Takafumi
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アクセス権 | ||||||||||
アクセス権 | open access | |||||||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||
内容記述 | ||||||||||
内容記述タイプ | Other | |||||||||
内容記述 | Nucleotide sequences of a part of the stromal cell-derived factor-1 (SDF-1) gene 3´ untranslated region were studied among hominoids (chimpanzees, gorillas, orangutans and gibbons). An identical sequence to the human SDF1-3´G allele was found in chimpanzees and gibbons, whereas that to the 3´A allele was found in gorillas. Based on the sequence data and the hominoid phylogenetic relation, it was suggested that an adenine nucleotide at nucleotide position (np) 801 in humans and gorillas was independently introduced into each lineage after the specific divergence and an ancestral hominoid sequence of this site (np 799-802) was deduced as CCGG. The present data showing a mutational hot spot on this site suggest the possible presence of multiple origins of the worldwide distribution of the SDF1-3´A allele in humans. | |||||||||
内容記述 | ||||||||||
内容記述タイプ | Other | |||||||||
内容記述 | 論文 | |||||||||
出版者 | ||||||||||
言語 | en | |||||||||
出版者 | Wayne State University Press | |||||||||
言語 | ||||||||||
言語 | eng | |||||||||
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資源タイプ | journal article | |||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
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出版タイプ | VoR | |||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||
識別子 | ||||||||||
識別子 | http://hdl.handle.net/20.500.12000/47017 | |||||||||
識別子タイプ | HDL | |||||||||
関連情報 | ||||||||||
識別子タイプ | DOI | |||||||||
関連識別子 | https://doi.org/10.1353/hub.2001.0084 | |||||||||
関連情報 | ||||||||||
識別子タイプ | DOI | |||||||||
関連識別子 | https://doi.org/10.1353/hub.2001.0084 | |||||||||
収録物識別子 | ||||||||||
収録物識別子タイプ | ISSN | |||||||||
収録物識別子 | 0018-7143 | |||||||||
収録物名 | ||||||||||
言語 | en | |||||||||
収録物名 | Human Biology | |||||||||
書誌情報 |
巻 73, 号 6, p. 891-895, 発行日 2001-12 |