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  1. 学術雑誌論文
  2. その他
  1. 部局別インデックス
  2. 医学部

The role of polymorphisms associated with early tooth eruption in dental and occlusal traits in East Asian populations

http://hdl.handle.net/20.500.12000/47018
http://hdl.handle.net/20.500.12000/47018
1486af0a-66c2-4759-b40b-d65dc666c739
名前 / ファイル ライセンス アクション
kjod-44-96.pdf kjod-44-96.pdf
Item type デフォルトアイテムタイプ(フル)(1)
公開日 2020-10-20
タイトル
タイトル The role of polymorphisms associated with early tooth eruption in dental and occlusal traits in East Asian populations
言語 en
作成者 Yamaguchi, Tetsutaro

× Yamaguchi, Tetsutaro

en Yamaguchi, Tetsutaro

Kawaguchi, Akira

× Kawaguchi, Akira

en Kawaguchi, Akira

Kim, Yong-Il

× Kim, Yong-Il

en Kim, Yong-Il

Haga, Shugo

× Haga, Shugo

en Haga, Shugo

Katayama, Koshu

× Katayama, Koshu

en Katayama, Koshu

Ishida, Hajime

× Ishida, Hajime

en Ishida, Hajime

Park, Soo-Byung

× Park, Soo-Byung

en Park, Soo-Byung

Maki, Koutaro

× Maki, Koutaro

en Maki, Koutaro

Kimura, Ryosuke

× Kimura, Ryosuke

en Kimura, Ryosuke

アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利情報
言語 en
権利情報 Creative Commons Attribution-NonCommercial 3.0
言語 en
権利情報Resource https://creativecommons.org/licenses/by-nc/3.0/
権利情報 https://creativecommons.org/licenses/by-nc/3.0/
主題
言語 en
主題Scheme Other
主題 Genetics
言語 en
主題Scheme Other
主題 Tooth size
言語 en
主題Scheme Other
主題 Orthodontic index
内容記述
内容記述タイプ Other
内容記述 Objective: A recent study suggested that rs6504340, a polymorphism within the homeobox B (HOXB) gene cluster, is associated with the susceptibility for malocclusions in Europeans. The resulting malocclusions require orthodontic treatment. The aim of this study was to investigate the association of rs6504340 and other dentition-implicated polymorphisms with dental and occlusal traits in Korean and Japanese populations. Methods: The study participants included 223 unrelated Koreans from the Busan area and 256 unrelated Japanese individuals from the Tokyo metropolitan area. DNA samples were extracted from saliva specimens. Genotyping for rs6504340 and four single nucleotide polymorphisms (SNPs) that have been shown to be associated with the timing of first tooth eruption and the number of teeth at 1 year of age (rs10506525, rs1956529, rs9674544, and rs8079702) was performed using TaqMan assays. The Index of Orthodontic Treatment Need (IOTN), overjet, overbite, arch length discrepancy, crown sizes, and length and width of the dental arches were measured. Spearman’s correlation coefficients were calculated to evaluate relationships between rs6504340 and these dental/occlusal traits. Results: We evaluated the aesthetic components and dental health components of the IOTN in the Korean and Japanese populations and found that neither rs6504340 nor the other four SNPs showed any association with dental and occlusal traits in these East Asian populations. Conclusions: These negative results suggest that further research is needed to identify the genetic determinants of malocclusions in order to reach a consensus.
内容記述タイプ Other
内容記述 論文
出版者
言語 en
出版者 The Korean Association of Orthodontists
言語
言語 eng
資源タイプ
資源タイプ journal article
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
識別子
識別子 http://hdl.handle.net/20.500.12000/47018
識別子タイプ HDL
関連情報
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.4041/kjod.2014.44.2.96
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.4041/kjod.2014.44.2.96
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 2234-7518
収録物識別子タイプ ISSN
収録物識別子 2005-372X
収録物名
言語 en
収録物名 The Korean Journal of Orthodontics
書誌情報
巻 44, 号 2, p. 96-102
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