Item type |
デフォルトアイテムタイプ(フル)(1) |
公開日 |
2020-10-20 |
タイトル |
|
|
タイトル |
The role of polymorphisms associated with early tooth eruption in dental and occlusal traits in East Asian populations |
|
言語 |
en |
作成者 |
Yamaguchi, Tetsutaro
Kawaguchi, Akira
Kim, Yong-Il
Haga, Shugo
Katayama, Koshu
Ishida, Hajime
Park, Soo-Byung
Maki, Koutaro
Kimura, Ryosuke
|
アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
権利情報 |
|
|
言語 |
en |
|
権利情報 |
Creative Commons Attribution-NonCommercial 3.0 |
権利情報 |
|
|
言語 |
en |
|
権利情報Resource |
https://creativecommons.org/licenses/by-nc/3.0/ |
|
権利情報 |
https://creativecommons.org/licenses/by-nc/3.0/ |
主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Genetics |
主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Tooth size |
主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Orthodontic index |
内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
Objective: A recent study suggested that rs6504340, a polymorphism within the homeobox B (HOXB) gene cluster, is associated with the susceptibility for malocclusions in Europeans. The resulting malocclusions require orthodontic treatment. The aim of this study was to investigate the association of rs6504340 and other dentition-implicated polymorphisms with dental and occlusal traits in Korean and Japanese populations. Methods: The study participants included 223 unrelated Koreans from the Busan area and 256 unrelated Japanese individuals from the Tokyo metropolitan area. DNA samples were extracted from saliva specimens. Genotyping for rs6504340 and four single nucleotide polymorphisms (SNPs) that have been shown to be associated with the timing of first tooth eruption and the number of teeth at 1 year of age (rs10506525, rs1956529, rs9674544, and rs8079702) was performed using TaqMan assays. The Index of Orthodontic Treatment Need (IOTN), overjet, overbite, arch length discrepancy, crown sizes, and length and width of the dental arches were measured. Spearman’s correlation coefficients were calculated to evaluate relationships between rs6504340 and these dental/occlusal traits. Results: We evaluated the aesthetic components and dental health components of the IOTN in the Korean and Japanese populations and found that neither rs6504340 nor the other four SNPs showed any association with dental and occlusal traits in these East Asian populations. Conclusions: These negative results suggest that further research is needed to identify the genetic determinants of malocclusions in order to reach a consensus. |
内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
論文 |
出版者 |
|
|
言語 |
en |
|
出版者 |
The Korean Association of Orthodontists |
言語 |
|
|
言語 |
eng |
資源タイプ |
|
|
資源タイプ |
journal article |
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
識別子 |
|
|
識別子 |
http://hdl.handle.net/20.500.12000/47018 |
|
識別子タイプ |
HDL |
関連情報 |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.4041/kjod.2014.44.2.96 |
関連情報 |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.4041/kjod.2014.44.2.96 |
収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
2234-7518 |
収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
2005-372X |
収録物名 |
|
|
言語 |
en |
|
収録物名 |
The Korean Journal of Orthodontics |
書誌情報 |
巻 44,
号 2,
p. 96-102,
発行日 2014
|