Item type |
デフォルトアイテムタイプ(フル)(1) |
公開日 |
2020-11-16 |
タイトル |
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タイトル |
Intestinal helminth infections in HIV-infected patients in Savannakhet after establishment of an HIV registration network in Lao People’s Democratic Republic |
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言語 |
ja |
作成者 |
Kaneshiro, Yukako
Sourinphoumy, Khamphang
Imaizumi, Naoki
Rasaphon, Mangkhalar
Kuba-Miyara, Megumi
Sakihama, Shugo
Guerrero, Carmina Louise Hugo
Nhativong, Ketsaphone
Nonaka, Daisuke
Pongvongsa, Tiengkham
Kobayashi, Jun
Kounnavong, Sengchanh
Fukushima, Takuya
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アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
権利情報 |
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言語 |
en |
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権利情報 |
Creative Commons Attribution 4.0 |
権利情報 |
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言語 |
en |
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権利情報Resource |
https://creativecommons.org/licenses/by/4.0/ |
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権利情報 |
https://creativecommons.org/licenses/by/4.0/ |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
Human immunodeficiency virus |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
Helminth infections |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
Human T cell leukemia virus type I |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
Registration network |
主題 |
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言語 |
ja |
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主題Scheme |
Other |
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主題 |
Lao People’s Democratic Republic |
内容記述 |
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内容記述タイプ |
Other |
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内容記述 |
Background: In Lao People’s Democratic Republic (PDR), which borders China, Vietnam, Cambodia, Thailand, and Myanmar, the number of HIV-infected patients has increased in recent years. HIV-infected patients diagnosed in Lao PDR are enrolled in a registration network and receive antiretroviral therapy (ART) covered by governmental financial support. Based on the registration network, we investigated intestinal helminth infections and coinfection with HTLV-1 in HIV-infected patients treated with an early intervention using ART in Lao PDR.\nMethods: This cross-sectional study of all 252 HIV-infected patients at Savannakhet Provincial Hospital, located in the southern part of Lao PDR, was conducted between February and March 2018. Socioepidemiological information and clinical information were collected from a registration network database and by questionnaire administered to participants. Microscopic examination of intestinal helminth infections in stool samples and particle agglutination for anti-HTLV-1 antibody in plasma were performed.\nResults: The median age of all 252 participants was 39 years old (range, 18–59). Based on the registration network database, there were 156 (61.9%) HIV-infected patients with a CD4-positive cell count ≥ 200 cells/μL and 146 (57.9%) with an HIV viral load < 250 copies/mL. Among 212 stool samples, 75 (35.4%) were found to contain one or more intestinal helminth species, including Opisthorchis viverrini (16.5%), Strongyloides stercoralis (10.8%), hookworm (10.4%), and Taenia saginata (3.3%). This rate of intestinal helminth infections was lower than that of a previous report conducted before the establishment of the registration network for HIV-infected patients in Lao PDR. There was no significant association between intestinal helminth infections and a lower CD4-positive T cell count or higher HIV viral load. HIV-infected patients with anti-HTLV-1 antibody positivity were not found in this cohort.\nConclusion: The registration network and an early intervention using ART may provide good medical care and improve the clinical course of HIV-infected patients in Lao PDR. However, the incidence of intestinal helminth infections remains high at 35.4%. The development of a specific medical care system for helminth infection for HIV-infected patients is necessary. |
内容記述 |
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内容記述タイプ |
Other |
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内容記述 |
論文 |
出版者 |
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言語 |
en |
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出版者 |
Springer Nature |
言語 |
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言語 |
eng |
資源タイプ |
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資源タイプ |
journal article |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
出版タイプ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
識別子 |
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識別子 |
http://hdl.handle.net/20.500.12000/47230 |
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識別子タイプ |
HDL |
関連情報 |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1186/s41182-019-0142-0 |
関連情報 |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1186/s41182-019-0142-0 |
収録物識別子 |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
1349-4147 |
収録物名 |
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言語 |
en |
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収録物名 |
Tropical Medicine and Health |
書誌情報 |
巻 47,
発行日 2019-02-11
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