ログイン
言語:

WEKO3

  • トップ
  • ランキング
To
lat lon distance
To

Field does not validate



インデックスリンク

インデックスツリー

メールアドレスを入力してください。

WEKO

One fine body…

WEKO

One fine body…

アイテム

{"_buckets": {"deposit": "92026936-0b29-4346-9b1a-f94e5501d719"}, "_deposit": {"id": "2011233", "owners": [1], "pid": {"revision_id": 0, "type": "depid", "value": "2011233"}, "status": "published"}, "_oai": {"id": "oai:u-ryukyu.repo.nii.ac.jp:02011233", "sets": ["1642838338003", "1642838407795"]}, "author_link": [], "item_1617186331708": {"attribute_name": "Title", "attribute_value_mlt": [{"subitem_1551255647225": "Effectiveness of Subcutaneous Growth Hormone in HIV-1 Patients with Moderate to Severe Facial Lipoatrophy", "subitem_1551255648112": "en"}]}, "item_1617186419668": {"attribute_name": "Creator", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Honda, Miwako", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Yogi, Akira", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Ishizuka, Naoki", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Genka, Ikumi", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Gatanaga, Hiroyuki", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Teruya, Katsuji", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Tachikawa, Natsuo", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Kikuchi, Yoshimi", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Oka, Shinichi", "creatorNameLang": "en"}]}]}, "item_1617186476635": {"attribute_name": "Access Rights", "attribute_value_mlt": [{"subitem_1522299639480": "open access", "subitem_1600958577026": "http://purl.org/coar/access_right/c_abf2"}]}, "item_1617186499011": {"attribute_name": "Rights", "attribute_value_mlt": [{"subitem_1522650717957": "en", "subitem_1522651041219": "Creative Commons Attribution-NonCommercial-NoDerivatives 4.0"}, {"subitem_1522650717957": "en", "subitem_1522650727486": "https://creativecommons.org/licenses/by-nc-nd/4.0/", "subitem_1522651041219": "https://creativecommons.org/licenses/by-nc-nd/4.0/"}]}, "item_1617186609386": {"attribute_name": "Subject", "attribute_value_mlt": [{"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "HIV"}, {"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "antiretroviral treatment"}, {"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "lipoatrophy"}, {"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "recombinant human growth hormone"}]}, "item_1617186626617": {"attribute_name": "Description", "attribute_value_mlt": [{"subitem_description": "Objective: To evaluate effect of recombinant human growth hormone (rhGH) among HIV-infected adults with moderate to severe facial lipoatrophy as a side effect of long-term antiretroviral treatment.\\nDesign: A prospective open-label study\\nMethods: Twenty-five HIV-1 patients with moderate to severe facial lipoatrophy who had been on antiretroviral treatment for more than 18 months were enrolled. rhGH (5 mg) was given every other day for 6 months. After treatment was completed, the participants were followed up for 6 months. Facial lipoatrophy was evaluated by computed tomography at months 0, 3, 6 and 12.\\nResults: Nearly all participants (24 of 25) completed the study. The sum of bilateral soft tissue thickness at the level of zygomatics at months 0, 3, 6, 12 were 7.23, 8.59, 8.35, 8.60 mm, respectively. There was significant improvement from baseline in month 3 (p=0.009) and month 12 (p=0.021). In the 6 months of follow-up, the soft tissue showed no significant decrease. Several side effects including diarrhea, arthralgia, myalgia, mastalgia and hand numbness were seen, which were self-limited and transient.\\nConclusion: rhGH is effective and relatively safe for moderate to severe facial lipoatrophy. Its effect was sustained at least for 6 months after the cessation of rhGH.", "subitem_description_type": "Other"}, {"subitem_description": "\u8ad6\u6587", "subitem_description_type": "Other"}]}, "item_1617186643794": {"attribute_name": "Publisher", "attribute_value_mlt": [{"subitem_1522300295150": "en", "subitem_1522300316516": "The Japanese Society of Internal Medicine"}, {"subitem_1522300295150": "ja", "subitem_1522300316516": "\u4e00\u822c\u793e\u56e3\u6cd5\u4eba\u3000\u65e5\u672c\u5185\u79d1\u5b66\u4f1a"}]}, "item_1617186702042": {"attribute_name": "Language", "attribute_value_mlt": [{"subitem_1551255818386": "eng"}]}, "item_1617186783814": {"attribute_name": "Identifier", "attribute_value_mlt": [{"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/20.500.12000/47242"}]}, "item_1617186920753": {"attribute_name": "Source Identifier", "attribute_value_mlt": [{"subitem_1522646500366": "ISSN", "subitem_1522646572813": "1349-7235"}, {"subitem_1522646500366": "ISSN", "subitem_1522646572813": "0918-2918"}]}, "item_1617186941041": {"attribute_name": "Source Title", "attribute_value_mlt": [{"subitem_1522650068558": "en", "subitem_1522650091861": "Internal Medicine"}]}, "item_1617187056579": {"attribute_name": "Bibliographic Information", "attribute_value_mlt": [{"bibliographicIssueNumber": "7", "bibliographicPageEnd": "362", "bibliographicPageStart": "359", "bibliographicVolumeNumber": "46"}]}, "item_1617258105262": {"attribute_name": "Resource Type", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_1617265215918": {"attribute_name": "Version Type", "attribute_value_mlt": [{"subitem_1522305645492": "VoR", "subitem_1600292170262": "http://purl.org/coar/version/c_970fb48d4fbd8a85"}]}, "item_1617353299429": {"attribute_name": "Relation", "attribute_value_mlt": [{"subitem_1522306287251": {"subitem_1522306382014": "DOI", "subitem_1522306436033": "https://doi.org/10.2169/internalmedicine.46.6122"}}, {"subitem_1522306287251": {"subitem_1522306382014": "DOI", "subitem_1522306436033": "https://doi.org/10.2169/internalmedicine.46.6122"}}]}, "item_1617605131499": {"attribute_name": "File", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_access", "download_preview_message": "", "file_order": 0, "filename": "46_7_359.pdf", "future_date_message": "", "is_thumbnail": false, "mimetype": "", "size": 0, "url": {"objectType": "fulltext", "url": "https://u-ryukyu.repo.nii.ac.jp/record/2011233/files/46_7_359.pdf"}, "version_id": "ecf738b9-2292-414a-9671-41cacde09dc5"}]}, "item_title": "Effectiveness of Subcutaneous Growth Hormone in HIV-1 Patients with Moderate to Severe Facial Lipoatrophy", "item_type_id": "15", "owner": "1", "path": ["1642838338003", "1642838407795"], "permalink_uri": "http://hdl.handle.net/20.500.12000/47242", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2020-11-16"}, "publish_date": "2020-11-16", "publish_status": "0", "recid": "2011233", "relation": {}, "relation_version_is_last": true, "title": ["Effectiveness of Subcutaneous Growth Hormone in HIV-1 Patients with Moderate to Severe Facial Lipoatrophy"], "weko_shared_id": -1}
  1. 学術雑誌論文
  2. その他
  1. 部局別インデックス
  2. 医学部

Effectiveness of Subcutaneous Growth Hormone in HIV-1 Patients with Moderate to Severe Facial Lipoatrophy

http://hdl.handle.net/20.500.12000/47242
http://hdl.handle.net/20.500.12000/47242
f32e9b2c-9eb6-4db0-bf7f-132d2ac1ce03
名前 / ファイル ライセンス アクション
46_7_359.pdf 46_7_359.pdf
Item type デフォルトアイテムタイプ(フル)(1)
公開日 2020-11-16
タイトル
タイトル Effectiveness of Subcutaneous Growth Hormone in HIV-1 Patients with Moderate to Severe Facial Lipoatrophy
言語 en
作成者 Honda, Miwako

× Honda, Miwako

en Honda, Miwako

Yogi, Akira

× Yogi, Akira

en Yogi, Akira

Ishizuka, Naoki

× Ishizuka, Naoki

en Ishizuka, Naoki

Genka, Ikumi

× Genka, Ikumi

en Genka, Ikumi

Gatanaga, Hiroyuki

× Gatanaga, Hiroyuki

en Gatanaga, Hiroyuki

Teruya, Katsuji

× Teruya, Katsuji

en Teruya, Katsuji

Tachikawa, Natsuo

× Tachikawa, Natsuo

en Tachikawa, Natsuo

Kikuchi, Yoshimi

× Kikuchi, Yoshimi

en Kikuchi, Yoshimi

Oka, Shinichi

× Oka, Shinichi

en Oka, Shinichi

アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利情報
言語 en
権利情報 Creative Commons Attribution-NonCommercial-NoDerivatives 4.0
言語 en
権利情報Resource https://creativecommons.org/licenses/by-nc-nd/4.0/
権利情報 https://creativecommons.org/licenses/by-nc-nd/4.0/
主題
言語 en
主題Scheme Other
主題 HIV
言語 en
主題Scheme Other
主題 antiretroviral treatment
言語 en
主題Scheme Other
主題 lipoatrophy
言語 en
主題Scheme Other
主題 recombinant human growth hormone
内容記述
内容記述タイプ Other
内容記述 Objective: To evaluate effect of recombinant human growth hormone (rhGH) among HIV-infected adults with moderate to severe facial lipoatrophy as a side effect of long-term antiretroviral treatment.\nDesign: A prospective open-label study\nMethods: Twenty-five HIV-1 patients with moderate to severe facial lipoatrophy who had been on antiretroviral treatment for more than 18 months were enrolled. rhGH (5 mg) was given every other day for 6 months. After treatment was completed, the participants were followed up for 6 months. Facial lipoatrophy was evaluated by computed tomography at months 0, 3, 6 and 12.\nResults: Nearly all participants (24 of 25) completed the study. The sum of bilateral soft tissue thickness at the level of zygomatics at months 0, 3, 6, 12 were 7.23, 8.59, 8.35, 8.60 mm, respectively. There was significant improvement from baseline in month 3 (p=0.009) and month 12 (p=0.021). In the 6 months of follow-up, the soft tissue showed no significant decrease. Several side effects including diarrhea, arthralgia, myalgia, mastalgia and hand numbness were seen, which were self-limited and transient.\nConclusion: rhGH is effective and relatively safe for moderate to severe facial lipoatrophy. Its effect was sustained at least for 6 months after the cessation of rhGH.
内容記述タイプ Other
内容記述 論文
出版者
言語 ja
出版者 一般社団法人 日本内科学会
言語
言語 eng
資源タイプ
資源タイプ journal article
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
識別子
識別子 http://hdl.handle.net/20.500.12000/47242
識別子タイプ HDL
関連情報
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.2169/internalmedicine.46.6122
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.2169/internalmedicine.46.6122
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 1349-7235
収録物識別子タイプ ISSN
収録物識別子 0918-2918
収録物名
言語 en
収録物名 Internal Medicine
書誌情報
巻 46, 号 7, p. 359-362
戻る
0
views
See details
Views

Versions

Ver.1 2022-02-01 06:38:50.928857
Show All versions

Share

Mendeley Twitter Facebook Print Addthis

Cite as

エクスポート

OAI-PMH
  • OAI-PMH JPCOAR
  • OAI-PMH DublinCore
  • OAI-PMH DDI
Other Formats
  • JSON

確認


Powered by WEKO3


Powered by WEKO3