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アイテム
Characterization of CTX-M-type-extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae isolated from Indonesian undergraduate medical students of a university in Surabaya, Indonesia
http://hdl.handle.net/20.500.12000/47431
http://hdl.handle.net/20.500.12000/474314f795c61-4757-4a9c-a269-0e30c5cf4fe8
| 名前 / ファイル | ライセンス | アクション |
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hokenken22digest.pdf
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hokenken22review.pdf
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hokenken22abstract.pdf
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| Item type | デフォルトアイテムタイプ（フル）(1) | |||||||
|---|---|---|---|---|---|---|---|---|
| 公開日 | 2020-12-08 | |||||||
| タイトル | ||||||||
| タイトル | Characterization of CTX-M-type-extended-spectrum beta-lactamase (ESBL)-producing Enterobacteriaceae isolated from Indonesian undergraduate medical students of a university in Surabaya, Indonesia | |||||||
| 言語 | en | |||||||
| 作成者 |
Rosantia, Sarassari
× Rosantia, Sarassari
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| アクセス権 | ||||||||
| アクセス権 | embargoed access | |||||||
| アクセス権URI | http://purl.org/coar/access_right/c_f1cf | |||||||
| 主題 | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | ESBL-Producing Enterobacteriaceae | |||||||
| 主題 | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | Medical student | |||||||
| 主題 | ||||||||
| 言語 | en | |||||||
| 主題Scheme | Other | |||||||
| 主題 | Clonal | |||||||
| 内容記述 | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | Enterobacteriaceae isolates producing CTX-M-type extended-spectrum b-lactamase (ESBL) has been found in hospitalized patients and healthy individuals in communities of the Southeast Asian countries. Medical students might have more risk of ESBL-producing Enterobacteriaceae contagion, because medical students who belong to communities have direct and indirect contacts with workers and patients in healthcare facilities. The aim of this study was to collect information for evaluation of the potential risk of ESBL-producing Enterobacteriaceae contagion in Indonesian undergraduate medical students by characterizing genotypic properties of Escherichia coli isolates-producing CTX-M-type ESBL. A total 141 fecal samples collected from 207 medical students of a university in Surabaya, Indonesia were subjected to PCR, XbaI and S1 nuclease-pulsed-field gel electrophoresis (PFGE), Southern blotting, and sequencing analysis. Eighty-two ESBL-producing Enterobacteriaceae, including 75 E. coli and 7 Klebsiella pneumoniae were isolated from 79 (56.0%) students. Among 75 ESBL-producing E. coli, blaCTX-M-15 was the most prevalent type (44.0%). Although XbaI-PFGE results showed genetic background of the E. coli isolates producing CTX-M-type ESBL were diverse, five clonal spread cases of certain E. coli producing CTX-Mtype ESBL isolates were observed among the medical students. Our results suggested that ESBLproducing Enterobacteriaceae might be circulating among the medical students through contaminated environment such as in a university or communities they belonged. | |||||||
| 内容記述 | ||||||||
| 内容記述タイプ | Other | |||||||
| 内容記述 | 学位論文 | |||||||
| 出版者 | ||||||||
| 出版者 | University of the Ryukyus | |||||||
| 言語 | en | |||||||
| 言語 | ||||||||
| 言語 | eng | |||||||
| 資源タイプ | ||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||||
| 資源タイプ | doctoral thesis | |||||||
| 識別子 | ||||||||
| 識別子 | http://hdl.handle.net/20.500.12000/47431 | |||||||
| 識別子タイプ | HDL | |||||||
| 関連情報 | ||||||||
| 識別子タイプ | DOI | |||||||
| 関連識別子 | https://doi.org/10.1016/j.jiac.2020.01.010 | |||||||
| 関連情報 | ||||||||
| 識別子タイプ | DOI | |||||||
| 関連識別子 | https://doi.org/10.1016/j.jiac.2020.01.010 | |||||||
| 収録物名 | ||||||||
| 収録物名 | Journal of Infection and Chemotherapy | |||||||
| 言語 | en | |||||||
| 書誌情報 |
巻 26, 号 6, p. 575-581, 発行日 2020-06 |
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| 学位授与番号 | ||||||||
| 学位授与番号 | 甲第22号 | |||||||
| 学位名 | ||||||||
| 言語 | ja | |||||||
| 学位名 | 博士（保健学） | |||||||
| 学位授与年月日 | ||||||||
| 学位授与年月日 | 2020-09-18 | |||||||
| 学位授与機関 | ||||||||
| 学位授与機関識別子Scheme | kakenhi | |||||||
| 学位授与機関識別子 | 18001 | |||||||
| 言語 | ja | |||||||
| 学位授与機関名 | 琉球大学 | |||||||
