Item type |
デフォルトアイテムタイプ(フル)(1) |
公開日 |
2020-12-22 |
タイトル |
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タイトル |
Humeral head histopathological changes in cuff tear arthropathy |
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言語 |
en |
作成者 |
Toma, Takashi
Suenaga, Naoki
Taniguchi, Noboru
Oizumi, Naomi
Yamaguchi, Hiroshi
Tome, Yasunori
Kanaya, Fuminori
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アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
権利情報 |
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言語 |
en |
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権利情報 |
Creative Commons Attribution-NonCommercial 4.0 |
権利情報 |
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言語 |
en |
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権利情報Resource |
https://creativecommons.org/licenses/by-nc/4.0/ |
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権利情報 |
https://creativecommons.org/licenses/by-nc/4.0/ |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
Cuff tear arthropathy |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
humeral head |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
osteoarthritis |
内容記述 |
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内容記述タイプ |
Other |
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内容記述 |
Purpose: The aim of this study was to investigate the histopathological changes in the humeral head in cuff tear arthropathy (CTA) compared with those in glenohumeral osteoarthritis (OA) and humeral neck fracture, which served as non-cuff tear controls.\nMethods: Twenty-three humeral heads extracted at the time of shoulder prosthesis arthroplasty between June 2014 and July 2015 were evaluated in the present study. The diagnoses included four-part humeral neck fracture (n = 4; average age, 85.0 years), glenohumeral OA (n = 4; average age, 71.0 years), and CTA (n = 15; average age, 73.0 years). The humeral heads were evaluated pathologically by hematoxylin and eosin and Safranin-O staining, and the thickness of the articular cartilage was measured.\nResults: Fibrillation, thinning, and tearing of the cartilage were observed in the superior area of the humeral heads in CTA and glenohumeral OA. In CTA cases, clusters of chondrocytes in the cartilage were observed. Moreover, the thickness of the cartilage layer in the middle of the humeral head was 1.54 ± 0.07, 0.32 ± 0.46, and 2.19 ± 0.50 mm in humeral neck fracture, glenohumeral OA, and CTA, respectively. The cartilage layer in CTA was thicker than that in glenohumeral OA (CTA vs. OA: p < 0.05).\nConclusion: OA changes in the superior area of the humeral heads and thickening of the cartilage layer from the middle to the inferior of the humeral heads were confirmed histopathologically, suggesting that simultaneous mechanical and nutritional factors might be contributing to CTA pathogenesis. The current study provided the better understanding of cartilage damage and thickening in CTA. This will help guide treatment options in the setting of CTA. |
内容記述 |
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内容記述タイプ |
Other |
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内容記述 |
論文 |
出版者 |
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言語 |
en |
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出版者 |
SAGE Publications |
言語 |
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言語 |
eng |
資源タイプ |
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資源タイプ |
journal article |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
出版タイプ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
識別子 |
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識別子 |
http://hdl.handle.net/20.500.12000/47566 |
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識別子タイプ |
HDL |
関連情報 |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1177/2309499018816428 |
関連情報 |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1177/2309499018816428 |
収録物識別子 |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
2309-4990 |
収録物名 |
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言語 |
en |
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収録物名 |
Journal of Orthopaedic Surgery |
書誌情報 |
巻 27,
号 1,
p. 1-6,
発行日 2018-12-04
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