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  1. 学術雑誌論文
  2. その他
  1. 部局別インデックス
  2. 国際地域創造学部

Sibling number and prevalence of allergic disorders in pregnant Japanese women: baseline data from the Kyushu Okinawa Maternal and Child Health Study

http://hdl.handle.net/20.500.12000/47770
http://hdl.handle.net/20.500.12000/47770
b420dfe3-abb7-43f2-9d99-7c3c9b2efb35
名前 / ファイル ライセンス アクション
1471-2458-11-561.pdf 1471-2458-11-561.pdf
Item type デフォルトアイテムタイプ(フル)(1)
公開日 2021-03-02
タイトル
タイトル Sibling number and prevalence of allergic disorders in pregnant Japanese women: baseline data from the Kyushu Okinawa Maternal and Child Health Study
言語 en
作成者 Miyake, Yoshihiro

× Miyake, Yoshihiro

en Miyake, Yoshihiro

Tanaka, Keiko

× Tanaka, Keiko

en Tanaka, Keiko

Arakawa, Masashi

× Arakawa, Masashi

en Arakawa, Masashi

アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利情報
言語 en
権利情報 Creative Commons Attribution 2.0
言語 en
権利情報Resource http://creativecommons.org/licenses/by/2.0
権利情報 http://creativecommons.org/licenses/by/2.0
内容記述
内容記述タイプ Other
内容記述 Background: Although an inverse relationship between number of siblings and likelihood of allergic disorders has been shown in many epidemiological studies, the biological mechanism underlying this phenomenon has not yet been identified. There is no epidemiological research regarding the sibling effect on allergic disorders in Japanese adults. The current cross-sectional study examined the relationship between number of siblings and prevalence of allergic disorders among adult women in Japan. Methods: Subjects were 1745 pregnant women. This study was based on questionnaire data. The definitions of wheeze and asthma were based on criteria from the European Community Respiratory Health Survey whereas those of eczema and rhinoconjunctivitis were based on criteria from the International Study of Asthma and Allergies in Childhood. Adjustment was made for age, region of residence, pack-years of smoking, secondhand smoke exposure at home and at work, family history of asthma, atopic eczema, and allergic rhinitis, household income, and education. Results: The prevalence values of wheeze, asthma, eczema, and rhinoconjunctivitis in the past 12 months were 10.4%, 5.5%, 13.0%, and 25.9%, respectively. A significant inverse exposure-response relationship was observed between the number of older siblings and rhinoconjunctivitis, but not wheeze, asthma, or eczema (P for trend = 0.03); however, the adjusted odds ratio (OR) for having 2 or more older siblings was not significant although the adjusted OR for having 1 older sibling was statistically significant (adjusted OR = 0.71 [95% CI: 0.56-0.91]). Number of total siblings and number of younger siblings were not related to wheeze, asthma, eczema, or rhinoconjunctivitis. Conclusions: This study found a significant inverse relationship between the number of older siblings and the prevalence of rhinoconjunctivitis among pregnant Japanese women. Our findings are likely to support the intrauterine programming hypothesis; however, we could not rule out the hygiene hypothesis.
内容記述タイプ Other
内容記述 論文
出版者
言語 en
出版者 BioMed Central
言語
言語 eng
資源タイプ
資源タイプ journal article
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
識別子
識別子 http://hdl.handle.net/20.500.12000/47770
識別子タイプ HDL
関連情報
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.1186/1471-2458-11-561
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.1186/1471-2458-11-561
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 1471-2458
収録物名
言語 en
収録物名 BMC Public Health
書誌情報
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