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Sibling number and prevalence of allergic disorders in pregnant Japanese women: baseline data from the Kyushu Okinawa Maternal and Child Health Study
http://hdl.handle.net/20.500.12000/47770
http://hdl.handle.net/20.500.12000/47770b420dfe3-abb7-43f2-9d99-7c3c9b2efb35
名前 / ファイル | ライセンス | アクション |
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1471-2458-11-561.pdf
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Item type | デフォルトアイテムタイプ(フル)(1) | |||||||||||
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公開日 | 2021-03-02 | |||||||||||
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タイトル | Sibling number and prevalence of allergic disorders in pregnant Japanese women: baseline data from the Kyushu Okinawa Maternal and Child Health Study | |||||||||||
言語 | en | |||||||||||
作成者 |
Miyake, Yoshihiro
× Miyake, Yoshihiro
× Tanaka, Keiko
× Arakawa, Masashi
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アクセス権 | open access | |||||||||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||||
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言語 | en | |||||||||||
権利情報 | Creative Commons Attribution 2.0 | |||||||||||
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言語 | en | |||||||||||
権利情報Resource | http://creativecommons.org/licenses/by/2.0 | |||||||||||
権利情報 | http://creativecommons.org/licenses/by/2.0 | |||||||||||
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内容記述タイプ | Other | |||||||||||
内容記述 | Background: Although an inverse relationship between number of siblings and likelihood of allergic disorders has been shown in many epidemiological studies, the biological mechanism underlying this phenomenon has not yet been identified. There is no epidemiological research regarding the sibling effect on allergic disorders in Japanese adults. The current cross-sectional study examined the relationship between number of siblings and prevalence of allergic disorders among adult women in Japan. Methods: Subjects were 1745 pregnant women. This study was based on questionnaire data. The definitions of wheeze and asthma were based on criteria from the European Community Respiratory Health Survey whereas those of eczema and rhinoconjunctivitis were based on criteria from the International Study of Asthma and Allergies in Childhood. Adjustment was made for age, region of residence, pack-years of smoking, secondhand smoke exposure at home and at work, family history of asthma, atopic eczema, and allergic rhinitis, household income, and education. Results: The prevalence values of wheeze, asthma, eczema, and rhinoconjunctivitis in the past 12 months were 10.4%, 5.5%, 13.0%, and 25.9%, respectively. A significant inverse exposure-response relationship was observed between the number of older siblings and rhinoconjunctivitis, but not wheeze, asthma, or eczema (P for trend = 0.03); however, the adjusted odds ratio (OR) for having 2 or more older siblings was not significant although the adjusted OR for having 1 older sibling was statistically significant (adjusted OR = 0.71 [95% CI: 0.56-0.91]). Number of total siblings and number of younger siblings were not related to wheeze, asthma, eczema, or rhinoconjunctivitis. Conclusions: This study found a significant inverse relationship between the number of older siblings and the prevalence of rhinoconjunctivitis among pregnant Japanese women. Our findings are likely to support the intrauterine programming hypothesis; however, we could not rule out the hygiene hypothesis. | |||||||||||
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内容記述タイプ | Other | |||||||||||
内容記述 | 論文 | |||||||||||
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言語 | en | |||||||||||
出版者 | BioMed Central | |||||||||||
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言語 | eng | |||||||||||
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資源タイプ | journal article | |||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
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出版タイプ | VoR | |||||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||
識別子 | ||||||||||||
識別子 | http://hdl.handle.net/20.500.12000/47770 | |||||||||||
識別子タイプ | HDL | |||||||||||
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識別子タイプ | DOI | |||||||||||
関連識別子 | https://doi.org/10.1186/1471-2458-11-561 | |||||||||||
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識別子タイプ | DOI | |||||||||||
関連識別子 | https://doi.org/10.1186/1471-2458-11-561 | |||||||||||
収録物識別子 | ||||||||||||
収録物識別子タイプ | ISSN | |||||||||||
収録物識別子 | 1471-2458 | |||||||||||
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言語 | en | |||||||||||
収録物名 | BMC Public Health | |||||||||||
書誌情報 |
巻 11, 発行日 2011-07-14 |