{"_buckets": {"deposit": "e9978523-8f46-401e-abe2-e15e9e046fee"}, "_deposit": {"id": "2012388", "owners": [1], "pid": {"revision_id": 0, "type": "depid", "value": "2012388"}, "status": "published"}, "_oai": {"id": "oai:u-ryukyu.repo.nii.ac.jp:02012388", "sets": ["1642838338003", "1642838407795"]}, "author_link": [], "item_1617186331708": {"attribute_name": "Title", "attribute_value_mlt": [{"subitem_1551255647225": "A Unique Subset of \u03b3\u03b4 T Cells Expands and Produces IL-10 in Patients with Naturally Acquired Immunity against Falciparum Malaria", "subitem_1551255648112": "ja"}]}, "item_1617186419668": {"attribute_name": "Creator", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Taniguchi, Tomoyo", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Mannoor, Kaiissar Md", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Nonaka, Daisuke", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Toma, Hiromu", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Li, Changchun", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Narita, Miwako", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Vanisaveth, Viengxay", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Kano, Shigeyuki", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Takahashi, Masuhiro", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Watanabe, Hisami", "creatorNameLang": "en"}]}]}, "item_1617186476635": {"attribute_name": "Access Rights", "attribute_value_mlt": [{"subitem_1522299639480": "open access", "subitem_1600958577026": "http://purl.org/coar/access_right/c_abf2"}]}, "item_1617186499011": {"attribute_name": "Rights", "attribute_value_mlt": [{"subitem_1522650717957": "en", "subitem_1522651041219": "Creative Commons Attribution 4.0"}, {"subitem_1522650717957": "en", "subitem_1522650727486": "https://creativecommons.org/licenses/by/4.0/", "subitem_1522651041219": "https://creativecommons.org/licenses/by/4.0/"}]}, "item_1617186609386": {"attribute_name": "Subject", "attribute_value_mlt": [{"subitem_1522299896455": "ja", "subitem_1522300014469": "Other", "subitem_1523261968819": "\u03b3\u03b4 T cells"}, {"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "naturally acquired immunity"}, {"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "Plasmodium falciparum"}, {"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "falciparum malaria"}, {"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "IL-10"}]}, "item_1617186626617": {"attribute_name": "Description", "attribute_value_mlt": [{"subitem_description": "Although expansions in gamma delta T cell populations are known to occur in the peripheral blood of patients infected with Plasmodium falciparum, the role of these cells in people with naturally acquired immunity against P. falciparum who live in malaria-endemic areas is poorly understood. We used a cross-sectional survey to investigate the role of peripheral blood gamma delta T cells in people living in Lao People\u0027s Democratic Republic, a malaria-endemic area. We found that the proportion of non-V gamma 9 gamma delta T cells was higher in non-hospitalized uncomplicated falciparum malaria patients (UMPs) from this region. Notably, we found that the non-V gamma 9 gamma delta T cells in the peripheral blood of UMPs and negative controls from this region had the potential to expand and produce IL-10 and interferon-gamma when cultured in the presence of IL-2 and/or crude P. falciparum antigens for 10 days. Furthermore, these cells were associated with plasma interleukin 10 (IL-10), which was elevated in UMPs. This is the first report demonstrating that, in UMPs living in a malaria-endemic area, a gamma delta T cell subset, the non-V gamma 9 gamma delta T cells, expands and produces IL-10. These results contribute to understanding of the mechanisms of naturally acquired immunity against P. falciparum.", "subitem_description_type": "Other"}, {"subitem_description": "\u8ad6\u6587", "subitem_description_type": "Other"}]}, "item_1617186643794": {"attribute_name": "Publisher", "attribute_value_mlt": [{"subitem_1522300295150": "en", "subitem_1522300316516": "Frontiers Media"}]}, "item_1617186702042": {"attribute_name": "Language", "attribute_value_mlt": [{"subitem_1551255818386": "eng"}]}, "item_1617186783814": {"attribute_name": "Identifier", "attribute_value_mlt": [{"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/20.500.12000/45905"}]}, "item_1617186920753": {"attribute_name": "Source Identifier", "attribute_value_mlt": [{"subitem_1522646500366": "ISSN", "subitem_1522646572813": "1664-302X"}]}, "item_1617186941041": {"attribute_name": "Source Title", "attribute_value_mlt": [{"subitem_1522650068558": "en", "subitem_1522650091861": "Frontiers in Microbiology"}]}, "item_1617187056579": {"attribute_name": "Bibliographic Information", "attribute_value_mlt": [{"bibliographicVolumeNumber": "8"}]}, "item_1617258105262": {"attribute_name": "Resource Type", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_1617265215918": {"attribute_name": "Version Type", "attribute_value_mlt": [{"subitem_1522305645492": "VoR", "subitem_1600292170262": "http://purl.org/coar/version/c_970fb48d4fbd8a85"}]}, "item_1617353299429": {"attribute_name": "Relation", "attribute_value_mlt": [{"subitem_1522306287251": {"subitem_1522306382014": "DOI", "subitem_1522306436033": "https://doi.org/10.3389/fmicb.2017.01288"}}, {"subitem_1522306287251": {"subitem_1522306382014": "DOI", "subitem_1522306436033": "https://doi.org/10.3389/fmicb.2017.01288"}}]}, "item_1617605131499": {"attribute_name": "File", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_access", "download_preview_message": "", "file_order": 0, "filename": "fmicb-08-01288.pdf", "future_date_message": "", "is_thumbnail": false, "mimetype": "", "size": 0, "url": {"objectType": "fulltext", "url": "https://u-ryukyu.repo.nii.ac.jp/record/2012388/files/fmicb-08-01288.pdf"}, "version_id": "5c58c69f-f139-46e7-91c3-305e35e21a5f"}]}, "item_title": "A Unique Subset of \u03b3\u03b4 T Cells Expands and Produces IL-10 in Patients with Naturally Acquired Immunity against Falciparum Malaria", "item_type_id": "15", "owner": "1", "path": ["1642838338003", "1642838407795"], "permalink_uri": "http://hdl.handle.net/20.500.12000/45905", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2020-05-27"}, "publish_date": "2020-05-27", "publish_status": "0", "recid": "2012388", "relation": {}, "relation_version_is_last": true, "title": ["A Unique Subset of \u03b3\u03b4 T Cells Expands and Produces IL-10 in Patients with Naturally Acquired Immunity against Falciparum Malaria"], "weko_shared_id": -1}