ログイン
言語:

WEKO3

  • トップ
  • ランキング
To
lat lon distance
To

Field does not validate



インデックスリンク

インデックスツリー

メールアドレスを入力してください。

WEKO

One fine body…

WEKO

One fine body…

アイテム

{"_buckets": {"deposit": "e9978523-8f46-401e-abe2-e15e9e046fee"}, "_deposit": {"id": "2012388", "owners": [1], "pid": {"revision_id": 0, "type": "depid", "value": "2012388"}, "status": "published"}, "_oai": {"id": "oai:u-ryukyu.repo.nii.ac.jp:02012388", "sets": ["1642838338003", "1642838407795"]}, "author_link": [], "item_1617186331708": {"attribute_name": "Title", "attribute_value_mlt": [{"subitem_1551255647225": "A Unique Subset of γδ T Cells Expands and Produces IL-10 in Patients with Naturally Acquired Immunity against Falciparum Malaria", "subitem_1551255648112": "ja"}]}, "item_1617186419668": {"attribute_name": "Creator", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Taniguchi, Tomoyo", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Mannoor, Kaiissar Md", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Nonaka, Daisuke", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Toma, Hiromu", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Li, Changchun", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Narita, Miwako", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Vanisaveth, Viengxay", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Kano, Shigeyuki", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Takahashi, Masuhiro", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Watanabe, Hisami", "creatorNameLang": "en"}]}]}, "item_1617186476635": {"attribute_name": "Access Rights", "attribute_value_mlt": [{"subitem_1522299639480": "open access", "subitem_1600958577026": "http://purl.org/coar/access_right/c_abf2"}]}, "item_1617186499011": {"attribute_name": "Rights", "attribute_value_mlt": [{"subitem_1522650717957": "en", "subitem_1522651041219": "Creative Commons Attribution 4.0"}, {"subitem_1522650717957": "en", "subitem_1522650727486": "https://creativecommons.org/licenses/by/4.0/", "subitem_1522651041219": "https://creativecommons.org/licenses/by/4.0/"}]}, "item_1617186609386": {"attribute_name": "Subject", "attribute_value_mlt": [{"subitem_1522299896455": "ja", "subitem_1522300014469": "Other", "subitem_1523261968819": "γδ T cells"}, {"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "naturally acquired immunity"}, {"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "Plasmodium falciparum"}, {"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "falciparum malaria"}, {"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "IL-10"}]}, "item_1617186626617": {"attribute_name": "Description", "attribute_value_mlt": [{"subitem_description": "Although expansions in gamma delta T cell populations are known to occur in the peripheral blood of patients infected with Plasmodium falciparum, the role of these cells in people with naturally acquired immunity against P. falciparum who live in malaria-endemic areas is poorly understood. We used a cross-sectional survey to investigate the role of peripheral blood gamma delta T cells in people living in Lao People\u0027s Democratic Republic, a malaria-endemic area. We found that the proportion of non-V gamma 9 gamma delta T cells was higher in non-hospitalized uncomplicated falciparum malaria patients (UMPs) from this region. Notably, we found that the non-V gamma 9 gamma delta T cells in the peripheral blood of UMPs and negative controls from this region had the potential to expand and produce IL-10 and interferon-gamma when cultured in the presence of IL-2 and/or crude P. falciparum antigens for 10 days. Furthermore, these cells were associated with plasma interleukin 10 (IL-10), which was elevated in UMPs. This is the first report demonstrating that, in UMPs living in a malaria-endemic area, a gamma delta T cell subset, the non-V gamma 9 gamma delta T cells, expands and produces IL-10. These results contribute to understanding of the mechanisms of naturally acquired immunity against P. falciparum.", "subitem_description_type": "Other"}, {"subitem_description": "論文", "subitem_description_type": "Other"}]}, "item_1617186643794": {"attribute_name": "Publisher", "attribute_value_mlt": [{"subitem_1522300295150": "en", "subitem_1522300316516": "Frontiers Media"}]}, "item_1617186702042": {"attribute_name": "Language", "attribute_value_mlt": [{"subitem_1551255818386": "eng"}]}, "item_1617186783814": {"attribute_name": "Identifier", "attribute_value_mlt": [{"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/20.500.12000/45905"}]}, "item_1617186920753": {"attribute_name": "Source Identifier", "attribute_value_mlt": [{"subitem_1522646500366": "ISSN", "subitem_1522646572813": "1664-302X"}]}, "item_1617186941041": {"attribute_name": "Source Title", "attribute_value_mlt": [{"subitem_1522650068558": "en", "subitem_1522650091861": "Frontiers in Microbiology"}]}, "item_1617187056579": {"attribute_name": "Bibliographic Information", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2017-07-19", "bibliographicIssueDateType": "Issued"}, "bibliographicVolumeNumber": "8"}]}, "item_1617258105262": {"attribute_name": "Resource Type", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_1617265215918": {"attribute_name": "Version Type", "attribute_value_mlt": [{"subitem_1522305645492": "VoR", "subitem_1600292170262": "http://purl.org/coar/version/c_970fb48d4fbd8a85"}]}, "item_1617353299429": {"attribute_name": "Relation", "attribute_value_mlt": [{"subitem_1522306287251": {"subitem_1522306382014": "DOI", "subitem_1522306436033": "https://doi.org/10.3389/fmicb.2017.01288"}}, {"subitem_1522306287251": {"subitem_1522306382014": "DOI", "subitem_1522306436033": "https://doi.org/10.3389/fmicb.2017.01288"}}]}, "item_1617605131499": {"attribute_name": "File", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_access", "download_preview_message": "", "file_order": 0, "filename": "fmicb-08-01288.pdf", "future_date_message": "", "is_thumbnail": false, "mimetype": "", "size": 0, "url": {"objectType": "fulltext", "url": "https://u-ryukyu.repo.nii.ac.jp/record/2012388/files/fmicb-08-01288.pdf"}, "version_id": "5c58c69f-f139-46e7-91c3-305e35e21a5f"}]}, "item_title": "A Unique Subset of γδ T Cells Expands and Produces IL-10 in Patients with Naturally Acquired Immunity against Falciparum Malaria", "item_type_id": "15", "owner": "1", "path": ["1642838338003", "1642838407795"], "permalink_uri": "http://hdl.handle.net/20.500.12000/45905", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2020-05-27"}, "publish_date": "2020-05-27", "publish_status": "0", "recid": "2012388", "relation": {}, "relation_version_is_last": true, "title": ["A Unique Subset of γδ T Cells Expands and Produces IL-10 in Patients with Naturally Acquired Immunity against Falciparum Malaria"], "weko_shared_id": -1}
  1. 学術雑誌論文
  2. その他
  1. 部局別インデックス
  2. 医学部

A Unique Subset of γδ T Cells Expands and Produces IL-10 in Patients with Naturally Acquired Immunity against Falciparum Malaria

http://hdl.handle.net/20.500.12000/45905
http://hdl.handle.net/20.500.12000/45905
b0491c23-ba1d-4276-925e-7b70ac77f5d3
名前 / ファイル ライセンス アクション
fmicb-08-01288.pdf fmicb-08-01288.pdf
Item type デフォルトアイテムタイプ(フル)(1)
公開日 2020-05-27
タイトル
タイトル A Unique Subset of γδ T Cells Expands and Produces IL-10 in Patients with Naturally Acquired Immunity against Falciparum Malaria
言語 ja
作成者 Taniguchi, Tomoyo

× Taniguchi, Tomoyo

en Taniguchi, Tomoyo

Search repository
Mannoor, Kaiissar Md

× Mannoor, Kaiissar Md

en Mannoor, Kaiissar Md

Search repository
Nonaka, Daisuke

× Nonaka, Daisuke

en Nonaka, Daisuke

Search repository
Toma, Hiromu

× Toma, Hiromu

en Toma, Hiromu

Search repository
Li, Changchun

× Li, Changchun

en Li, Changchun

Search repository
Narita, Miwako

× Narita, Miwako

en Narita, Miwako

Search repository
Vanisaveth, Viengxay

× Vanisaveth, Viengxay

en Vanisaveth, Viengxay

Search repository
Kano, Shigeyuki

× Kano, Shigeyuki

en Kano, Shigeyuki

Search repository
Takahashi, Masuhiro

× Takahashi, Masuhiro

en Takahashi, Masuhiro

Search repository
Watanabe, Hisami

× Watanabe, Hisami

en Watanabe, Hisami

Search repository
アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利情報
言語 en
権利情報 Creative Commons Attribution 4.0
権利情報
言語 en
権利情報Resource https://creativecommons.org/licenses/by/4.0/
権利情報 https://creativecommons.org/licenses/by/4.0/
主題
言語 ja
主題Scheme Other
主題 γδ T cells
主題
言語 en
主題Scheme Other
主題 naturally acquired immunity
主題
言語 en
主題Scheme Other
主題 Plasmodium falciparum
主題
言語 en
主題Scheme Other
主題 falciparum malaria
主題
言語 en
主題Scheme Other
主題 IL-10
内容記述
内容記述タイプ Other
内容記述 Although expansions in gamma delta T cell populations are known to occur in the peripheral blood of patients infected with Plasmodium falciparum, the role of these cells in people with naturally acquired immunity against P. falciparum who live in malaria-endemic areas is poorly understood. We used a cross-sectional survey to investigate the role of peripheral blood gamma delta T cells in people living in Lao People's Democratic Republic, a malaria-endemic area. We found that the proportion of non-V gamma 9 gamma delta T cells was higher in non-hospitalized uncomplicated falciparum malaria patients (UMPs) from this region. Notably, we found that the non-V gamma 9 gamma delta T cells in the peripheral blood of UMPs and negative controls from this region had the potential to expand and produce IL-10 and interferon-gamma when cultured in the presence of IL-2 and/or crude P. falciparum antigens for 10 days. Furthermore, these cells were associated with plasma interleukin 10 (IL-10), which was elevated in UMPs. This is the first report demonstrating that, in UMPs living in a malaria-endemic area, a gamma delta T cell subset, the non-V gamma 9 gamma delta T cells, expands and produces IL-10. These results contribute to understanding of the mechanisms of naturally acquired immunity against P. falciparum.
内容記述
内容記述タイプ Other
内容記述 論文
出版者
言語 en
出版者 Frontiers Media
言語
言語 eng
資源タイプ
資源タイプ journal article
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
識別子
識別子 http://hdl.handle.net/20.500.12000/45905
識別子タイプ HDL
関連情報
識別子タイプ DOI
関連識別子 https://doi.org/10.3389/fmicb.2017.01288
関連情報
識別子タイプ DOI
関連識別子 https://doi.org/10.3389/fmicb.2017.01288
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 1664-302X
収録物名
言語 en
収録物名 Frontiers in Microbiology
書誌情報
巻 8, 発行日 2017-07-19
戻る
0
views
See details
Views

Versions

Ver.1 2022-02-02 02:07:49.419643
Show All versions

Share

Mendeley Twitter Facebook Print Addthis

Cite as

エクスポート

OAI-PMH
  • OAI-PMH JPCOAR
  • OAI-PMH DublinCore
  • OAI-PMH DDI
Other Formats
  • JSON
  • BIBTEX

Confirm


Powered by WEKO3


Powered by WEKO3