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  1. 学術雑誌論文
  2. その他
  1. 部局別インデックス
  2. 医学部

Appropriate radiation dose for symptomatic relief and local control in patients with adult T cell leukemia/lymphoma

http://hdl.handle.net/20.500.12000/45947
http://hdl.handle.net/20.500.12000/45947
2a52ca85-0d73-4e73-b018-9085f45978a9
名前 / ファイル ライセンス アクション
rry068.pdf rry068.pdf
Item type デフォルトアイテムタイプ(フル)(1)
公開日 2020-05-29
タイトル
タイトル Appropriate radiation dose for symptomatic relief and local control in patients with adult T cell leukemia/lymphoma
言語 en
作成者 Maemoto, Hitoshi

× Maemoto, Hitoshi

en Maemoto, Hitoshi

Ariga, Takuro

× Ariga, Takuro

en Ariga, Takuro

Nakachi, Sawada

× Nakachi, Sawada

en Nakachi, Sawada

Toita, Takafumi

× Toita, Takafumi

en Toita, Takafumi

Hashimoto, Seiji

× Hashimoto, Seiji

en Hashimoto, Seiji

Heianna, Joichi

× Heianna, Joichi

en Heianna, Joichi

Shiina, Hideki

× Shiina, Hideki

en Shiina, Hideki

Kusada, Takeaki

× Kusada, Takeaki

en Kusada, Takeaki

Makino, Wataru

× Makino, Wataru

en Makino, Wataru

Kakinohana, Yasumasa

× Kakinohana, Yasumasa

en Kakinohana, Yasumasa

Miyagi, Takuya

× Miyagi, Takuya

en Miyagi, Takuya

Yamamoto, Yuichi

× Yamamoto, Yuichi

en Yamamoto, Yuichi

Morishima, Satoko

× Morishima, Satoko

en Morishima, Satoko

Masuzaki, Hiroaki

× Masuzaki, Hiroaki

en Masuzaki, Hiroaki

Murayama, Sadayuki

× Murayama, Sadayuki

en Murayama, Sadayuki

アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利情報
言語 en
権利情報 Creative Commons Attribution-NonCommercial 4.0
言語 en
権利情報Resource https://creativecommons.org/licenses/by-nc/4.0/
権利情報 https://creativecommons.org/licenses/by-nc/4.0/
主題
言語 en
主題Scheme Other
主題 radiotherapy
言語 en
主題Scheme Other
主題 adult T-cell leukemia/lymphoma
言語 en
主題Scheme Other
主題 human T-cell leukemia virus type 1
言語 en
主題Scheme Other
主題 palliative radiotherapy
内容記述
内容記述タイプ Other
内容記述 Adult T-cell leukemia/lymphoma (ATL) is an aggressive peripheral T-cell neoplasm that occurs only in patients with human T-cell leukemia virus type 1. No large study or randomized trial investigating radiotherapy (RT) for ATL has been performed. We retrospectively reviewed 55 courses of RT for 41 consecutive patients with ATL who underwent RT between 2000 and 2016 at our institutions. The results showed that RT for local ATL lesions can achieve symptomatic improvement in 92% of cases. Local remission, either complete remission (CR) or partial response (PR), was achieved in 100% of the patients (CR: 89%, PR: 11%) with ≥40 Gy irradiation. CR or PR was achieved in 71% (CR: 29%, PR: 43%) with 30–39 Gy and in 73% (CR: 6.7%, PR: 67%) with ≤29 Gy irradiation. The mean total radiation dose in the CR and PR groups differed significantly (38 vs 25 Gy, P = 0.0002). The maximum acute toxicity was Grade 0–2 in all patients, except for one patient experienced Grade 3 radiation dermatitis. In-field relapses occurred in 36% of patients, and the frequency of in-field relapses was 11%, 30% and 71% among those who achieved CR, PR and SD, respectively. All 9 patients who received total skin irradiation experienced cutaneous relapses, with a median of 63 days (range, 7–210 days). Almost all (39 of 41) patients with ATL experienced out-of-field progression after RT. In conclusion, RT was confirmed to be effective and safe for palliative treatment of local ATL lesions.
内容記述タイプ Other
内容記述 論文
出版者
言語 en
出版者 Oxford University Press
言語
言語 eng
資源タイプ
資源タイプ journal article
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
識別子
識別子 http://hdl.handle.net/20.500.12000/45947
識別子タイプ HDL
関連情報
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.1093/jrr/rry068
関連識別子
識別子タイプ DOI
関連識別子 https://doi.org/10.1093/jrr/rry068
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 0449-3060
収録物識別子タイプ ISSN
収録物識別子 1349-9157
収録物名
言語 en
収録物名 Journal of Radiation Research
書誌情報
巻 60, 号 1, p. 98-108
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