Item type |
デフォルトアイテムタイプ(フル)(1) |
公開日 |
2020-06-24 |
タイトル |
|
|
タイトル |
REDUCED EFFECT OF CHEMOTHERAPY OF STRONGYLOIDIASIS IN PATIENTS WITH CONCURRENT HTLV-I INFECTION IN OKINAWA, JAPAN |
|
言語 |
en |
タイトル |
|
|
タイトル |
糞線虫症の治療効果に及ぼすATLウイルス混合感染の影響 |
|
言語 |
ja |
作成者 |
Sato, Yoshiya
Shiroma, Yoshiyuki
Kiyuna, Susumu
Toma, Hiromu
Kobayashi, Jun
佐藤, 良也
城間, 祥行
喜友名, 進
當真, 弘
小林, 潤
|
アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
The effect of concurrent HTLV-I infection on the efficacy of anti-Strongyloides chemotherapy has been tested in a prognostic study on 96 patients with uncomplicated strongyloidiasis. The efficacy of treatment with pyrvinium pamoate and thiabendazole was found to be significantly low in the HTLV-I seropositive patients, as compared to that in the seronegative group. The cure rates in the HTLV-I seropositive patients, when assessed by both faecal examination and serological testing, were only 8.6% for pyrvinium pamoate treatment and 35.0% for thiabendazole treatment. On the other hand, the cure rates were 31.3% for pyrvinium pamoate treatment and 57.1% for thiabendazole treatment in the seronegative group.\nAlthough antibody response against Strongyloides did not decrease among the HTLVI seropositive patients, the total serum IgE levels, as well as eosinophil counts in peripheral blood, were relatively low in the seropositive group. Abnormal lymphocytes were demonstrated in 38.5% of the patients with concurrent HTLV-I infection. The presence of abnormal lymphocytes, however, appeared not to correlate with the therapeutic efficacy. A possible connection between the poor efficacy and depressed immune responses provided by the concurrent HTLV-I infection is discussed. The low efficacy in the HTLV-I seropositive patients also provides a causal explanation for the significant accumulation of patients with concurrent HTLV-I infection in Okinawa. |
内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
論文 |
出版者 |
|
|
言語 |
en |
|
出版者 |
Japanese Society of Tropical Medicine |
出版者 |
|
|
言語 |
ja |
|
出版者 |
日本熱帯医学会 |
言語 |
|
|
言語 |
eng |
資源タイプ |
|
|
資源タイプ |
journal article |
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
識別子 |
|
|
識別子 |
http://hdl.handle.net/20.500.12000/46267 |
|
識別子タイプ |
HDL |
関連情報 |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.2149/tmh1973.20.183 |
関連情報 |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.2149/tmh1973.20.183 |
収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
2186-1811 |
収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0304-2146 |
収録物名 |
|
|
言語 |
en |
|
収録物名 |
Japanese Journal of Tropical Medicine and Hygiene |
書誌情報 |
巻 20,
号 3,
p. 183-192,
発行日 1992-09-15
|