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  1. 学位論文
  2. 博士論文
  3. 医学研究科
  1. 部局別インデックス
  2. 医学研究科

偏光顕微鏡下に観察されるネザートン症候群の毛髪異常

http://hdl.handle.net/20.500.12000/46708
http://hdl.handle.net/20.500.12000/46708
7953b179-d984-42c0-beeb-2f6ab9f6b494
名前 / ファイル ライセンス アクション
iron228digest.pdf iron228digest.pdf
iron228review.pdf iron228review.pdf
iron228abstract.pdf iron228abstract.pdf
Item type デフォルトアイテムタイプ(フル)(1)
公開日 2020-09-16
タイトル
タイトル Hair Abnormality in Netherton Syndrome Observed under Polarized Light Microscopy
言語 en
タイトル
タイトル 偏光顕微鏡下に観察されるネザートン症候群の毛髪異常
言語 ja
作成者 Utsumi, Daisuke

× Utsumi, Daisuke

en Utsumi, Daisuke

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内海, 大介

× 内海, 大介

ja 内海, 大介

Search repository
アクセス権
アクセス権 embargoed access
アクセス権URI http://purl.org/coar/access_right/c_f1cf
主題
言語 en
主題Scheme Other
主題 diagnosis
主題
言語 en
主題Scheme Other
主題 Netherton syndrome
主題
言語 en
主題Scheme Other
主題 polarized light
主題
言語 en
主題Scheme Other
主題 polarized light microscopy
主題
言語 en
主題Scheme Other
主題 trichorrhexis invaginate
内容記述
内容記述タイプ Other
内容記述 Background: Trichorrhexis invaginata, the main diagnostic feature of Netherton syndrome, is often difficult to detect, especially in adult patients.<br/>Objective: We sought to describe a characteristic feature of hairs in Netherton syndrome using a polarized light microscope and the underlying histopathologic changes.<br/>Methods: Hairs obtained from 8 patients with Netherton syndrome were observed under polarized light, and we evaluated the correlation between number of band-like patterns and disease severity.<br/>Results: Under polarized microscopy, the hair shafts of 8 patients showed a characteristic band-like pattern under polarized light that was not observed in healthy control individuals or patients with atopic dermatitis. This discontinuity of polarized light shows a band-like pattern in which the bands mostly ranged from 0.1 to 1.0 mm in width. The observed ratio of this finding was significantly higher than that of trichorrhexis invaginata observed under light microscopy, and patients with severe dermatitis tended to have a higher ratio than those with less severe dermatitis.<br/>Limitations: Comparative examination among other congenital ichthyoses was not performed.<br/>Conclusions: A band-like pattern in hairs with polarized light microscopy can be seen in Netherton syndrome and may have potential utility as a diagnostic marker.
内容記述
内容記述タイプ Other
内容記述 学位論文
出版者
言語 en
出版者 University of the Ryukyus
出版者
言語 ja
出版者 琉球大学
言語
言語 eng
資源タイプ
資源タイプ doctoral thesis
資源タイプ識別子 http://purl.org/coar/resource_type/c_db06
識別子
識別子 http://hdl.handle.net/20.500.12000/46708
識別子タイプ HDL
関連情報
識別子タイプ DOI
関連識別子 https://doi.org/10.1016/j.jaad.2019.08.024
関連情報
識別子タイプ DOI
関連識別子 https://doi.org/10.1016/j.jaad.2019.08.024
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 0190-9622
収録物名
言語 en
収録物名 Journal of the American Academy of Dermatology
書誌情報
巻 83, 号 3, p. 847-853, 発行日 2020-09
学位授与番号
学位授与番号 乙第228号
学位名
学位名 博士(医学)
言語 ja
学位授与年月日
学位授与年月日 2020-02-26
学位授与機関
学位授与機関識別子 18001
学位授与機関識別子Scheme kakenhi
学位授与機関名 琉球大学
言語 ja
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