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偏光顕微鏡下に観察されるネザートン症候群の毛髪異常
http://hdl.handle.net/20.500.12000/46708
http://hdl.handle.net/20.500.12000/467087953b179-d984-42c0-beeb-2f6ab9f6b494
名前 / ファイル | ライセンス | アクション |
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Item type | デフォルトアイテムタイプ(フル)(1) | |||||||||
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公開日 | 2020-09-16 | |||||||||
タイトル | ||||||||||
タイトル | Hair Abnormality in Netherton Syndrome Observed under Polarized Light Microscopy | |||||||||
言語 | en | |||||||||
タイトル | ||||||||||
タイトル | 偏光顕微鏡下に観察されるネザートン症候群の毛髪異常 | |||||||||
言語 | ja | |||||||||
作成者 |
Utsumi, Daisuke
× Utsumi, Daisuke
× 内海, 大介
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アクセス権 | ||||||||||
アクセス権 | embargoed access | |||||||||
アクセス権URI | http://purl.org/coar/access_right/c_f1cf | |||||||||
主題 | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | diagnosis | |||||||||
主題 | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | Netherton syndrome | |||||||||
主題 | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | polarized light | |||||||||
主題 | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | polarized light microscopy | |||||||||
主題 | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | trichorrhexis invaginate | |||||||||
内容記述 | ||||||||||
内容記述タイプ | Other | |||||||||
内容記述 | Background: Trichorrhexis invaginata, the main diagnostic feature of Netherton syndrome, is often difficult to detect, especially in adult patients.<br/>Objective: We sought to describe a characteristic feature of hairs in Netherton syndrome using a polarized light microscope and the underlying histopathologic changes.<br/>Methods: Hairs obtained from 8 patients with Netherton syndrome were observed under polarized light, and we evaluated the correlation between number of band-like patterns and disease severity.<br/>Results: Under polarized microscopy, the hair shafts of 8 patients showed a characteristic band-like pattern under polarized light that was not observed in healthy control individuals or patients with atopic dermatitis. This discontinuity of polarized light shows a band-like pattern in which the bands mostly ranged from 0.1 to 1.0 mm in width. The observed ratio of this finding was significantly higher than that of trichorrhexis invaginata observed under light microscopy, and patients with severe dermatitis tended to have a higher ratio than those with less severe dermatitis.<br/>Limitations: Comparative examination among other congenital ichthyoses was not performed.<br/>Conclusions: A band-like pattern in hairs with polarized light microscopy can be seen in Netherton syndrome and may have potential utility as a diagnostic marker. | |||||||||
内容記述 | ||||||||||
内容記述タイプ | Other | |||||||||
内容記述 | 学位論文 | |||||||||
出版者 | ||||||||||
言語 | en | |||||||||
出版者 | University of the Ryukyus | |||||||||
出版者 | ||||||||||
言語 | ja | |||||||||
出版者 | 琉球大学 | |||||||||
言語 | ||||||||||
言語 | eng | |||||||||
資源タイプ | ||||||||||
資源タイプ | doctoral thesis | |||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||||||
識別子 | ||||||||||
識別子 | http://hdl.handle.net/20.500.12000/46708 | |||||||||
識別子タイプ | HDL | |||||||||
関連情報 | ||||||||||
識別子タイプ | DOI | |||||||||
関連識別子 | https://doi.org/10.1016/j.jaad.2019.08.024 | |||||||||
関連情報 | ||||||||||
識別子タイプ | DOI | |||||||||
関連識別子 | https://doi.org/10.1016/j.jaad.2019.08.024 | |||||||||
収録物識別子 | ||||||||||
収録物識別子タイプ | ISSN | |||||||||
収録物識別子 | 0190-9622 | |||||||||
収録物名 | ||||||||||
言語 | en | |||||||||
収録物名 | Journal of the American Academy of Dermatology | |||||||||
書誌情報 |
巻 83, 号 3, p. 847-853, 発行日 2020-09 |
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学位授与番号 | ||||||||||
学位授与番号 | 乙第228号 | |||||||||
学位名 | ||||||||||
学位名 | 博士(医学) | |||||||||
言語 | ja | |||||||||
学位授与年月日 | ||||||||||
学位授与年月日 | 2020-02-26 | |||||||||
学位授与機関 | ||||||||||
学位授与機関識別子 | 18001 | |||||||||
学位授与機関識別子Scheme | kakenhi | |||||||||
学位授与機関名 | 琉球大学 | |||||||||
言語 | ja |