Item type |
デフォルトアイテムタイプ(フル)(1) |
公開日 |
2020-10-05 |
タイトル |
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タイトル |
Development of the 12-item questionnaire for quantitative assessment of depressive mixed state (DMX-12) |
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言語 |
en |
作成者 |
Shinzato, Hotaka
Koda, Munenaga
Nakamura, Akifumi
Kondo, Tsuyoshi
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アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
権利情報 |
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言語 |
en |
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権利情報 |
Creative Commons Attribution-NonCommercial 3.0 |
権利情報 |
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言語 |
en |
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権利情報Resource |
https://creativecommons.org/licenses/by-nc/3.0/ |
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権利情報 |
https://creativecommons.org/licenses/by-nc/3.0/ |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
major depressive episode |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
depressive mixed state |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
spontaneous instability |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
vulnerable responsiveness |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
disruptive emotion/behavior |
内容記述 |
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内容記述タイプ |
Other |
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内容記述 |
Background: Conventional categorical criteria have limitations in assessing the prevalence and severity of depressive mixed state (DMX). Thus, we have developed a new scale for screening and quantification of DMX and examined the symptomatological structure and severity of DMX in individuals with major depressive episode (MDE).\nMethods: Subjects were 154 patients with MDE (57 males and 97 females; age 13-83 years). Our original Japanese version of the self-administered 12-item questionnaire to assess DMX (DMX-12), together with the Quick Inventory of Depressive Symptomatology Self-Report Japanese version (QIDS-SR-J) and global assessment of functioning, were administered to each participant. The symptomatological structure of the DMX-12 was examined by exploratory factor analysis. Multiple regression analyses were used to analyze factors contributing to the DMX-12 scale. The relationships of this scale with categorical diagnoses (mixed depression by Benazzi and mixed features by DSM-5) were also investigated.\nResults: A three-factor model of the DMX-12 was extracted from exploratory factor analysis, namely, "spontaneous instability", "vulnerable responsiveness", and "disruptive emotion/behavior". Multiple regression analyses revealed that age was negatively correlated with total DMX-12 score, while bipolarity and the QIDS-SR-J score were positively correlated. A higher score on the disruptive emotion/behavior subscale was observed in patients with mixed depression and mixed features.\nConclusion: The DMX-12 seems to be useful for screening DMX in conjunction with conventional categorical diagnoses. Severely depressed younger subjects with potential bipolarity are more likely to develop DMX. The disruptive emotion/behavior subscale of the DMX-12 may be the most helpful in distinguishing patients with DMX from non-mixed patients. |
内容記述 |
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内容記述タイプ |
Other |
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内容記述 |
論文 |
出版者 |
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言語 |
en |
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出版者 |
Dove Medical Press |
言語 |
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言語 |
eng |
資源タイプ |
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資源タイプ |
journal article |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
出版タイプ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
識別子 |
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識別子 |
http://hdl.handle.net/20.500.12000/46806 |
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識別子タイプ |
HDL |
関連情報 |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.2147/NDT.S215478 |
関連情報 |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.2147/NDT.S215478 |
収録物識別子 |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
1178-2021 |
収録物名 |
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言語 |
en |
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収録物名 |
Neuropsychiatric disease and treatment |
書誌情報 |
巻 15,
p. 1983-1991,
発行日 2019
|