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  1. 学術雑誌論文
  2. 琉球医学会
  3. 琉球大学医学会雑誌
  4. 11巻3-4号
  1. 部局別インデックス
  2. その他

[原著]末梢神経急性圧迫損傷に対する薬物療法の有効性に関する実験的研究 : 第一報,ステロイドの有効性について

http://hdl.handle.net/20.500.12000/0002015724
http://hdl.handle.net/20.500.12000/0002015724
da4db357-c5f0-4f9c-8404-1fc43696280a
名前 / ファイル ライセンス アクション
v11p141.pdf v11p141.pdf
Item type デフォルトアイテムタイプ(フル)(1)
公開日 2010-06-30
タイトル
タイトル [原著]末梢神経急性圧迫損傷に対する薬物療法の有効性に関する実験的研究 : 第一報,ステロイドの有効性について
言語 ja
作成者 武内, 正典

× 武内, 正典

ja 武内, 正典

Ian.M, Lowdon

× Ian.M, Lowdon

en Ian.M, Lowdon

茨木, 邦夫

× 茨木, 邦夫

ja 茨木, 邦夫

Takeuchi, Masanori

× Takeuchi, Masanori

en Takeuchi, Masanori

Lowdon, IanM

× Lowdon, IanM

en Lowdon, IanM

Ibaraki, Kunio

× Ibaraki, Kunio

en Ibaraki, Kunio

アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利情報
言語 ja
権利情報 琉球医学会
主題
言語 en
主題Scheme Other
主題 peripheral nerve
言語 en
主題Scheme Other
主題 compression injury
言語 en
主題Scheme Other
主題 steroid
言語 en
主題Scheme Other
主題 sciatic functional index (SFI)
内容記述
内容記述タイプ Other
内容記述 Steroids are often administered clinically for neural compression injjury. This study examines the effects of steroids on the function and histology of rat sciatic nerve following compression injury. The rat sciatic nerve with a silicone cuff applied was used as a model of acute compression injury. The application of this model to the study of an acute neural injury is made possible by the use of the sciatic functional index as a means of seqluentially monitoring the nerve deficit. Treatment with dexamethasone from before cuff application prevented functional deficit, but the histological appearance of the nerves examined was similar in both dexamethasone and normal saline administration groups. This suggests that the effect of the steroid was to reduce the severity of the injury only sifficiently to allow continuing function of a portion of the neurons. This study provides experimental evidence to support the use of steroids in the treatment of neural compression injury, but indicates that the functional benefits may mask continuing neuronal injury.
内容記述タイプ Other
内容記述 論文
出版者
言語 ja
出版者 琉球大学医学部
言語
言語 jpn
資源タイプ
資源タイプ journal article
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 0289-1530
収録物識別子タイプ NCID
収録物識別子 AN10027430
収録物名
言語 ja
収録物名 琉球大学医学会雑誌 : 医学部紀要 = Ryukyu medical journal
書誌情報
巻 11, 号 3-4, p. 141-145
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