Item type |
デフォルトアイテムタイプ(フル)(1) |
公開日 |
2010-06-30 |
タイトル |
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タイトル |
[原著]アルコール依存症者の事象関連電位と知的機能障害 |
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言語 |
ja |
タイトル |
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タイトル |
Event-Related Potentials and Intellectual Dysfunction in Chronic Alcoholics |
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言語 |
en |
作成者 |
宮里, 好一
小椋, 力
Miyazato, Yoshikazu
Ogura, Chikara
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アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
権利情報 |
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言語 |
ja |
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権利情報 |
琉球医学会 |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
alcoholism |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
event-related potential |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
ERP |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
intellectual dysfunction |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
P300 |
内容記述 |
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内容記述タイプ |
Other |
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内容記述 |
We reported the results of the event-related potentials (ERPs) and the intellectual dyfunction in chronic alcoholics. Ten male alcoholics and 10 age and sex matched healthy controls were tested. All alcoholics were inpatients who received medication. The alcoholics had been abstinent from alcohol fora period ranging from 20 days to 2 years. ERPs were recorded during prsentation of auditory stimuli using odd ball paradigm. The stimuli consisted of 1 KHz tone bursts referred to a frequent (non-target) stimuli and 2 KHz tone bursts referred to as rare (target) stimuli. The probabilities of frequent stimuli and rare stimuli were 0.8 and 0.2, respectively. The subjects were instructed to count the number of the rare tones. The EEG was recorded from midline frontal (Fz) , central (Cz). and parietal (Pz) referred to linked earlobes. The amplitudes of the various components were measured from a prestimulus baseline and were taken at the point of maximum positivity or negativity for the peak. The latencies were measured at the apex of each peak. For statistical analysis, analysis of variance and 2-tailed t-test were applied. While there were no differences for 3 components of ERPs(N100, P200, N200) between the alcoholies and the healthy controls, the amplitude of P300 was smaller in the alcoholies than the controls (at Fz, Cz, Pz; P<0.01-0.05). The latency of P300 was longer at Pz (p<0.05) in the alcoholics than the controls. With respect to the three psychometric tests, i.e. Hasegawa's dementia screnine scale, Benton's visual retention test and WAIS (digit span), the results were worse in the alcoholics than controls (P<0.01). Regardingthe relationship between the psychometric test and ERPs. there were the correlations for all psychometric tests and the amplitude and latency of P300 (pく0.01-0.05). |
内容記述 |
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内容記述タイプ |
Other |
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内容記述 |
論文 |
出版者 |
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言語 |
ja |
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出版者 |
琉球大学医学部 |
出版者 |
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言語 |
en |
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出版者 |
Faculty of Medicine, University of the Ryukyus |
言語 |
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言語 |
jpn |
資源タイプ |
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資源タイプ |
journal article |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
出版タイプ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
収録物識別子 |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
0289-1530 |
収録物識別子 |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AN10027430 |
収録物名 |
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言語 |
ja |
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収録物名 |
琉球大学医学会雑誌 : 医学部紀要 = Ryukyu medical journal |
書誌情報 |
巻 11,
号 2,
p. 80-89,
発行日 1989
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