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  1. 学術雑誌論文
  2. 琉球医学会
  3. 琉球大学医学会雑誌
  4. 11巻3-4号
  1. 部局別インデックス
  2. その他

[原著]再発悪性グリオ-マに対するIFN-β局所投与とACNU動注療法の試み

http://hdl.handle.net/20.500.12000/0002015793
http://hdl.handle.net/20.500.12000/0002015793
48d4c5fa-18c9-47ab-90cd-68d1a567da65
名前 / ファイル ライセンス アクション
v11p131.pdf v11p131.pdf
Item type デフォルトアイテムタイプ(フル)(1)
公開日 2010-06-30
タイトル
タイトル [原著]再発悪性グリオ-マに対するIFN-β局所投与とACNU動注療法の試み
言語 ja
作成者 仲宗根, 進

× 仲宗根, 進

ja 仲宗根, 進

六川, 二郎

× 六川, 二郎

ja 六川, 二郎

高良, 英一

× 高良, 英一

ja 高良, 英一

銘苅, 晋

× 銘苅, 晋

ja 銘苅, 晋

石川, 泰成

× 石川, 泰成

ja 石川, 泰成

久田, 均

× 久田, 均

ja 久田, 均

Nakasone, Susumu

× Nakasone, Susumu

en Nakasone, Susumu

Mukawa, Jiro

× Mukawa, Jiro

en Mukawa, Jiro

Takara, Eiichi

× Takara, Eiichi

en Takara, Eiichi

Mekaru, Susumu

× Mekaru, Susumu

en Mekaru, Susumu

Ishikawa, Yasunari

× Ishikawa, Yasunari

en Ishikawa, Yasunari

Kuda, Hitoshi

× Kuda, Hitoshi

en Kuda, Hitoshi

アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利情報
言語 ja
権利情報 琉球医学会
内容記述
内容記述タイプ Other
内容記述 Five cases of recurrent malignant gliomas were treated with local injection of interferon- βcombined with intracarotid injection of 1-(4-amino 2methy1-5-pyrimidinyl)methy1 -3-(2-chlor∝thy1)-3-nitrosourea hydrochloride(ACNU). All patients had been already treated with intravenous injection of IFN-β and/or ACNU as well as conventional radiotherapy after surgery. IFN-β(3×10^6 IU, 3 times a week) was locally injected through a catheter placed into tumor-removed cavity. ACNU (100mg/6weeks) was injected into the carotid artery following osmotic blood brain barrier modification produced by arterial injetion of 20% 200ml mannitol. Multiple intracranial lesions were checked with contrast enhanced CT in all cases. None of the cases exhibited clinical regression. But three of them showed tumor regression around the IFN-β injected cavity, although the other part of the tumor remained progressive. These results suggested that direct tumorddal effects of IFN-β was exhibited to recurrent malignant gliomas, and local injection of IFN-β is so useful that should be used from the initial stage in addition to its intravenous use. There should be some strategic ideas to overcome ACNU resistance when reused.
内容記述タイプ Other
内容記述 論文
出版者
言語 ja
出版者 琉球大学医学部
言語
言語 jpn
資源タイプ
資源タイプ journal article
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 0289-1530
収録物識別子タイプ NCID
収録物識別子 AN10027430
収録物名
言語 ja
収録物名 琉球大学医学会雑誌 : 医学部紀要 = Ryukyu medical journal
書誌情報
巻 11, 号 3-4, p. 131-140
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