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デフォルトアイテムタイプ(フル)(1) |
公開日 |
2010-07-02 |
タイトル |
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タイトル |
[原著]冠動脈病変の非侵嚢的検出法に関する研究 : 冠動脈造影検査と運動負荷タリウム心筋シンチグラフィ及び運動負荷心電図の比較 |
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言語 |
ja |
タイトル |
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タイトル |
Non-invasive Assessment of Organic Coronary Stenosis : Clinical Usefulness of Thallium-201 Myocardial Single Photon Emission Computed Tomography in Comparison with Exercise Electrocardiography |
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言語 |
en |
作成者 |
仲里, 政泰
加世田, 俊一
友利, 正行
丸岡, 雄二
柊山, 草志郎
勝山, 直文
Nakazato, Masayasu
Kaseda, Shunichi
Tomori, Masayuki
Maruoka, Yuji
Fukiyama, Koshiro
Katsuyama, Naofumi
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アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
権利情報 |
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言語 |
ja |
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権利情報 |
琉球医学会 |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
exercise thallium-201 myocardial scintigraphy |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
exercise ECG test |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
ischemic heart disease |
内容記述 |
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内容記述タイプ |
Other |
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内容記述 |
The purpose of this study was to evaluate clinical usefulness of exercise thallium-201 myocardial single photon emission computed tomography (Tl-ECT) to detect organic coronary stenosis noninvasively. One hundred thirty-one consecutive patients (34 to 79 years old, mean 58 y.o.) underwent coronary angiography, and their findings were compared with those of Tl-ECT or exercise ECG. In 100 patients who did not have myocardial infarction, sensitivity, specificity, predictive value and accurcy of Tl -ECT to detect organic coronary stenosis (luminal narrowingmore than 50% in coronary angiogram) were significantly higher than those of exercise ECG; 75% vs. 50% (p<0.05) , 75% vs. 44% (p<0.01), 63% vs 39% (p<0.01), and 75% vs. 46% (p<0.01), respectively. Peak heart rate, peak systolic blood pressure, peak pressure rate product and percentage of the age-predicted maximal heart rate at Tl-ECT test were not significantly different among patients with true positive and false negative results of Tl-ECT, suggesting that false negative results of Tl -ECT were not caused by lower achieved level of exercise in our study. Among 19 patients with variant angina, 4 showed false positive results of Tl-ECT. In 3 of these 4 patients, Tl-ECT was repeated after administration of calcium channel blocker. Perfusion defect observed at the first Tl-ECT test disappeared or became smaller in size in all 3 patients after the treatment. Thus, exercise-induced coronary vasospasm might have caused the exercise-induced perfusion defect in these patients with variant angina. In 31 patients with previous myocardial infarction, 25(81%) had perfusion defects, 6(19%) had no perfusion defects. Sensitivity of Tl-ECT was 93%. There was no false positive result, while false negative result were shown in 2 cases. To evaluate myocardial viability in 28 patients (13 with previous myocardial infarction, 15 without it) in whom redistribution of Tl-ECT was incomplete or absent, thallium imaging at rest was performed in other day. Improvement of myocardial thallium imaging was observed in 13 patients. We conclude that 1) Tl-ECT is more useful non-invasive test than exercise ECG for detection of organic coronary stenosis, 2) false positive results of Tl-ECT in variant angina might be caused by exercise-induced coronary vasospasm, 3) Tl-ECT at rest is indispensable to evaluate myocardial viability. |
内容記述 |
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内容記述タイプ |
Other |
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内容記述 |
論文 |
出版者 |
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言語 |
ja |
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出版者 |
琉球医学会 |
出版者 |
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言語 |
en |
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出版者 |
Ryukyu Medical Association |
言語 |
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言語 |
jpn |
資源タイプ |
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資源タイプ |
journal article |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
出版タイプ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
収録物識別子 |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
1346888X |
収録物識別子 |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
0289-1530 |
収録物識別子 |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AN10369445 |
収録物名 |
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言語 |
ja |
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収録物名 |
琉球医学会誌 = Ryukyu Medical Journal |
書誌情報 |
巻 12,
号 1,
p. 74-91,
発行日 1991
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