| Item type |
デフォルトアイテムタイプ（フル）(1) |
| 公開日 |
2010-07-02 |
| タイトル |
|
|
タイトル |
[原著］Effects of dietary supplementation of nucleoside-nucleotide mixture and its components upon graft vs host and host vs graft responses in mice |
|
言語 |
ja |
| 作成者 |
Kakinohana, Shige
Adjei, AndrewA
Ameho, ClementK
Yamauchi, Keiko
Wang, Ming-Fu
Chung, Hei-Mei
Yamamoto, Shigeru
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利情報 |
|
|
言語 |
ja |
|
権利情報 |
琉球医学会 |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
nucleosides |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
nucleotides |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
graft vs host |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
popliteal lymph node |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
mice |
| 内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
We studied the effects of individual components of a nucleoside-nucleotide mixture on the lymphocyte responses to allonantigens in popliteal lymph node (PLN) of mice. Mice were fed for 4 weeks a nucleotide-free 20% casein diet (control), or this diet supplemented with 3 mol/kg of one of the followings; inosine, guanosine monophosphate (GMP 2Na), uridine, cytidine, thymidine, or a mixture of these. In the graft vs host reaction, there was no difference in the PLN weights and the expression of CD4 and CD8 surface markers among the groups. In the host vs graft reaction there was a significant increase in the PLN weights between the mice fed the supplemented diets and the nucleotide-free dietary group (control). However, there was no difference between the mixture and the individual component diet groups. Except for GMP 2Na and cytidine supplemented groups, there was a difference in the expression of CD4 surface marker in the supplemented groups as compared to the control dietary group; the CD4^+ cells significantly increased in the supplemented groups, although there was no difference between the mixture and individual componenets supplemented groups. We conclude that mice fed the nucleoside-nucleotide mixture and the individual component of the mixture had enhancing effects in the host vs graft responses studied and that the effects in mice fed the mixture were not different from those in mice fed the individual component. |
| 内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
論文 |
| 出版者 |
|
|
出版者 |
琉球医学会 |
|
言語 |
ja |
| 出版者 |
|
|
出版者 |
Ryukyu Medical Association |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
1346888X |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0289-1530 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AN10369445 |
| 収録物名 |
|
|
収録物名 |
琉球医学会誌 = Ryukyu Medical Journal |
|
言語 |
ja |
| 書誌情報 |
巻 16,
号 4,
p. 165-170,
発行日 1996
|
v16p165.pdf
