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  1. 学術雑誌論文
  2. 琉球医学会
  3. 琉球医学会誌
  4. 16巻4号
  1. 部局別インデックス
  2. その他

[原著]Effects of dietary supplementation of nucleoside-nucleotide mixture and its components upon graft vs host and host vs graft responses in mice

http://hdl.handle.net/20.500.12000/0002015970
http://hdl.handle.net/20.500.12000/0002015970
841c5bc4-13fd-4ecd-99bd-988968ce17e1
名前 / ファイル ライセンス アクション
v16p165.pdf v16p165.pdf
Item type デフォルトアイテムタイプ(フル)(1)
公開日 2010-07-02
タイトル
タイトル [原著]Effects of dietary supplementation of nucleoside-nucleotide mixture and its components upon graft vs host and host vs graft responses in mice
言語 ja
作成者 Kakinohana, Shige

× Kakinohana, Shige

en Kakinohana, Shige

Adjei, AndrewA

× Adjei, AndrewA

en Adjei, AndrewA

Ameho, ClementK

× Ameho, ClementK

en Ameho, ClementK

Yamauchi, Keiko

× Yamauchi, Keiko

en Yamauchi, Keiko

Wang, Ming-Fu

× Wang, Ming-Fu

en Wang, Ming-Fu

Chung, Hei-Mei

× Chung, Hei-Mei

en Chung, Hei-Mei

Yamamoto, Shigeru

× Yamamoto, Shigeru

en Yamamoto, Shigeru

アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利情報
言語 ja
権利情報 琉球医学会
主題
言語 en
主題Scheme Other
主題 nucleosides
言語 en
主題Scheme Other
主題 nucleotides
言語 en
主題Scheme Other
主題 graft vs host
言語 en
主題Scheme Other
主題 popliteal lymph node
言語 en
主題Scheme Other
主題 mice
内容記述
内容記述タイプ Other
内容記述 We studied the effects of individual components of a nucleoside-nucleotide mixture on the lymphocyte responses to allonantigens in popliteal lymph node (PLN) of mice. Mice were fed for 4 weeks a nucleotide-free 20% casein diet (control), or this diet supplemented with 3 mol/kg of one of the followings; inosine, guanosine monophosphate (GMP 2Na), uridine, cytidine, thymidine, or a mixture of these. In the graft vs host reaction, there was no difference in the PLN weights and the expression of CD4 and CD8 surface markers among the groups. In the host vs graft reaction there was a significant increase in the PLN weights between the mice fed the supplemented diets and the nucleotide-free dietary group (control). However, there was no difference between the mixture and the individual component diet groups. Except for GMP 2Na and cytidine supplemented groups, there was a difference in the expression of CD4 surface marker in the supplemented groups as compared to the control dietary group; the CD4^+ cells significantly increased in the supplemented groups, although there was no difference between the mixture and individual componenets supplemented groups. We conclude that mice fed the nucleoside-nucleotide mixture and the individual component of the mixture had enhancing effects in the host vs graft responses studied and that the effects in mice fed the mixture were not different from those in mice fed the individual component.
内容記述タイプ Other
内容記述 論文
出版者
言語 ja
出版者 琉球医学会
言語
言語 eng
資源タイプ
資源タイプ journal article
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 1346888X
収録物識別子タイプ ISSN
収録物識別子 0289-1530
収録物識別子タイプ NCID
収録物識別子 AN10369445
収録物名
言語 ja
収録物名 琉球医学会誌 = Ryukyu Medical Journal
書誌情報
巻 16, 号 4, p. 165-170, 発行日 1996
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