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  1. 学術雑誌論文
  2. 琉球医学会
  3. 琉球医学会誌
  4. 17巻1号
  1. 部局別インデックス
  2. その他

[症例報告]A case report of hyperkeratotic lupus erythmatosus : An electron microscopic study of hyperkeratotic lesion

http://hdl.handle.net/20.500.12000/0002016067
http://hdl.handle.net/20.500.12000/0002016067
e5536115-17c0-48ff-8a3e-998b332d1f57
名前 / ファイル ライセンス アクション
v17p51.pdf v17p51.pdf
Item type デフォルトアイテムタイプ(フル)(1)
公開日 2010-07-02
タイトル
タイトル [症例報告]A case report of hyperkeratotic lupus erythmatosus : An electron microscopic study of hyperkeratotic lesion
言語 ja
作成者 Khaskhely, Noor Mohammad

× Khaskhely, Noor Mohammad

en Khaskhely, Noor Mohammad

Maruno, Motoyoshi

× Maruno, Motoyoshi

en Maruno, Motoyoshi

Hagiwara, Keisuke

× Hagiwara, Keisuke

en Hagiwara, Keisuke

Ramzi, SaeefTaher

× Ramzi, SaeefTaher

en Ramzi, SaeefTaher

Uesato, Hiroshi

× Uesato, Hiroshi

en Uesato, Hiroshi

Nonaka, Shigeo

× Nonaka, Shigeo

en Nonaka, Shigeo

Toda, Tekeyoshi

× Toda, Tekeyoshi

en Toda, Tekeyoshi

アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利情報
言語 ja
権利情報 琉球医学会
主題
言語 en
主題Scheme Other
主題 hyperkeratotic LE
言語 en
主題Scheme Other
主題 multilayered basement membrane
言語 en
主題Scheme Other
主題 fibroblasts and UV rays
内容記述
内容記述タイプ Other
内容記述 We report a case of hyperkeratotic lupus erythmatosus (LE) occurring on the dorsum of the right hand and the forearm of a 47-year old construction worker. Clinically, the hyperkeratotic LE lesions were scaly, revealing an indurated brownish margin and a wart-like appearance. Histopathologically, marked hyperkeratosis and acanthosis at the epidermis and solar elastosis of the upper dermis were observed. Serum immunoglobulins (IgG.IgA.IgM,) levels were increased, but there was no deposition of the immunoglobulins at the dermoepidermal junction in direct immunoflourescence examination. Electron microscopically the epidermal basement membrane was thick and partially multilayered, whereas the blood vessel walls were thickened and multilayered at the dermis. The collagen fibers were also thick and abundant, with many fibroblasts present at the upper dermis near the basement membrane zone. From these findings, we concluded that long term exposures to sun light might have damaged the photosensitive skin of LE patient. After repeated damage and repair, the collagen fibers had become thick and abundant with many fibroblasts at the upper dermis. Wecompared our case with those of Systemic Lupus Erythmatosus (SLE) and Discoid Lupus Erythmatosus (DLE) using electron microscopic and immunohistochemical techniques. We could not determine why some DLE patients show wart-like lesions while others do not.
内容記述タイプ Other
内容記述 論文
出版者
言語 ja
出版者 琉球医学会
言語
言語 eng
資源タイプ
資源タイプ journal article
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 1346888X
収録物識別子タイプ ISSN
収録物識別子 0289-1530
収録物識別子タイプ NCID
収録物識別子 AN10369445
収録物名
言語 ja
収録物名 琉球医学会誌 = Ryukyu Medical Journal
書誌情報
巻 17, 号 1, p. 51-56
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