| Item type |
デフォルトアイテムタイプ（フル）(1) |
| 公開日 |
2010-07-02 |
| タイトル |
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|
タイトル |
[原著]蛇唆症の血液学的研究 : 第一報 中国南部地域の蛇唆症の血液学的研究 |
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言語 |
ja |
| タイトル |
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タイトル |
Hematological studies on the snakebites : I. Hemostatic disturbances in snakebites in South China |
|
言語 |
en |
| 作成者 |
李, 其斌
余, 奇松
黄, 光武
渡慶次, 賀博
中村, 真理子
金城, 紀代彦
小杉忠誠
Li, Qi-Bin
Yu, Q.-S.
Huang, G.-W.
Tokeshi, yoshihiro
Nakamura, Mariko
Kinjoh, Kiyohiko
Kosugi, Tadayoshi
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| アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利情報 |
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|
言語 |
ja |
|
権利情報 |
琉球医学会 |
| 主題 |
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言語 |
en |
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主題Scheme |
Other |
|
主題 |
snakebite |
| 主題 |
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言語 |
en |
|
主題Scheme |
Other |
|
主題 |
antivenom |
| 主題 |
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|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
platelet function |
| 主題 |
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言語 |
en |
|
主題Scheme |
Other |
|
主題 |
coagulation-fibrinolysis system |
| 内容記述 |
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内容記述タイプ |
Other |
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内容記述 |
To study the hemostatic disturbances after snakebite, we measured the maximum platelet aggregation rate (MAR), antithrombin III (AT-III) activity, $ \alpha $_2 -plasmin inhibitor ( $ \alpha $_2 -PI) activity, fibrinogen concentration (Fg) and fibrin degradation products (FDP) in 17 patients with snakebite in South China from June 1996 to May 1997. The results obtained were as follows: 1) the mean MAR values in 15 samples from 13 patients before and without application of antivenom were markedly decreased in the case of snakebites from Vipera russelli (Vr.), Trimeresurus mucrosquamatus (Tm.) and Agkistrodon halys (Ah.); 2) the mean activities of AT-III were decreased in patients bitten by Deinagkistrodon acutus (Da.), Ah., Vr., Tm. and Naja naja atra (Nn.) but were not decreased in patients bitten by Trimeresurus stejnegeri (Ts.); 3) the mean activity of $ \alpha $_2-PI was decreased in all patients in the present study; 4) the mean concentration of fibrinogen (Fg) was markedly decreased in patients bitten by Da., Ah. and Vr., but was not decreased in the case of Nn. bite; and 5) the mean levels of FDP were increased in cases of Da.. Vr. and Ts. bite but not in Ah. and Tm. bite. After treatment using antivenom, the MAR, AT-III activity, $ \alpha $_2-PI activity and concentration of Fg in the patients with Nn. and Ah. bite were increased, but the FDP was not increased. In the case of patients who had been bitten by Vr. without treatment using antivenom, the hematological changes except for the AT-III activity did not return to normal levels within 45 hrs. The results of the present study indicate that disorders of platelet aggregation and the coagulation-fibrinolysis system are liable to occur in patients with snakebite from Da., Ah., Vr., Ts., Tm. and Nn. Furthermore, it appeared that DIC was evoked in some patients with these snakebites. Antivenom was found to be useful for improving the hemostatic disturbances after snakebite from Ah. and Nn. |
| 内容記述 |
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内容記述タイプ |
Other |
|
内容記述 |
論文 |
| 出版者 |
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出版者 |
琉球医学会 |
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言語 |
ja |
| 出版者 |
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出版者 |
Ryukyu Medical Association |
|
言語 |
en |
| 言語 |
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|
言語 |
jpn |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| 出版タイプ |
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|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 収録物識別子 |
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|
収録物識別子タイプ |
ISSN |
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収録物識別子 |
1346888X |
| 収録物識別子 |
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|
収録物識別子タイプ |
ISSN |
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収録物識別子 |
0289-1530 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AN10369445 |
| 収録物名 |
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|
収録物名 |
琉球医学会誌 = Ryukyu Medical Journal |
|
言語 |
ja |
| 書誌情報 |
巻 18,
号 1-2,
p. 27-32,
発行日 1998
|
v18p27.pdf
