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  1. 学術雑誌論文
  2. 琉球医学会
  3. 琉球医学会誌
  4. 23巻3号
  1. 部局別インデックス
  2. その他

[総説]心臓興奮伝播パターンの光学的マッピング

http://hdl.handle.net/20.500.12000/0002016199
http://hdl.handle.net/20.500.12000/0002016199
ad40211f-c112-408e-80d1-9503fe81599e
名前 / ファイル ライセンス アクション
v23p59.pdf v23p59.pdf
Item type デフォルトアイテムタイプ(フル)(1)
公開日 2010-07-02
タイトル
タイトル [総説]心臓興奮伝播パターンの光学的マッピング
言語 ja
作成者 酒井, 哲郎

× 酒井, 哲郎

ja 酒井, 哲郎

Sakai, Tetsuro

× Sakai, Tetsuro

en Sakai, Tetsuro

アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利情報
言語 ja
権利情報 琉球医学会
主題
言語 en
主題Scheme Other
主題 optical recording
言語 en
主題Scheme Other
主題 excitation spread
言語 en
主題Scheme Other
主題 mapping
言語 en
主題Scheme Other
主題 heart
内容記述
内容記述タイプ Other
内容記述 Optical methods for monitoring membrane potential with fast voltage-sensitive dyes have been introduced as a powerful tool for studying cardiac electrical functions. These methods offer two principal advantages over more conventional electrophysiological techniques. One is that it is possible to make optical recordings from very small cells which are inaccessible to microelectrode impalement, and the other is that multiple sites/regions of a preparation can be monitored simultaneously and provide spatially-resolved mapping of electrical activity. The former has made it possible to record spontaneous electrical activities in early embryonic pre-contractile hearts, and the later has been applied for the mapping of the propagation patterns of electrical activities in the cardiac tissue. In the course of optical studies of the excitation spread pattern of the vertebrate heart, we employed multiple-site optical recording of membrane potential activity, using a voltage-sensitive merocyanine-rhodanine dye (NK 2761) and a multiple-element photodiode array, to monitor action potentials in an isolated rat atrial preparation. We optically mapped the normal excitation spread pattern from the physiological pacemaker. We also mapped the excitation spread pattern during the events of tachycardia-like excitation (TE) evoked by electrical stimulation. These maps indicate that, during the event of TE, the excitatory waves were often rotated around the blocked area including ostium of the superior vena cava. The optical mapping during the initiation phase of TE indicated that the decrease of the conduction velocity and the appearance of blocked areas contributed the establishment of TE.
内容記述タイプ Other
内容記述 論文
出版者
言語 ja
出版者 琉球医学会
言語
言語 jpn
資源タイプ
資源タイプ journal article
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 1346888X
収録物識別子タイプ ISSN
収録物識別子 0289-1530
収録物識別子タイプ NCID
収録物識別子 AN10369445
収録物名
言語 ja
収録物名 琉球医学会誌 = Ryukyu Medical Journal
書誌情報
巻 23, 号 3, p. 59-70
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