Item type |
デフォルトアイテムタイプ(フル)(1) |
公開日 |
2021-11-18 |
タイトル |
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タイトル |
Usefulness of separately evaluating lymphatic and venous vessel invasion in cervical adenocarcinoma |
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言語 |
en |
作成者 |
Taira, Yusuke
Shimoji, Yuko
Nakasone, Tadaharu
Arakaki, Yoshihisa
Nakamoto, Tomoko
Ooyama, Takuma
Kudaka, Wataru
Kaneshima, Itomi
Nishihira, Kumiko
Aoki, Yoichi
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アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
権利情報 |
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言語 |
ja |
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権利情報 |
琉球医学会 |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
uterine cervical adenocarcinoma |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
lymph vessel invasion |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
venous vessel invasion |
内容記述 |
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内容記述タイプ |
Other |
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内容記述 |
Uterine cervical adenocarcinoma is less sensitive to radiation and chemotherapy than squamous cell carcinoma, and thus, its management includes surgical treatment. We evaluated lymphatic and venous vessel invasion separately in surgical specimens to predict prognosis and recurrence. We retrospectively analysed data from the medical records of 108 patients who were diagnosed with cervical adenocarcinoma or adenosquamous carcinoma and underwent abdominal radical hysterectomy in our institution from January 1993 to April 2017. Lymphatic and venous vessel invasion was separately evaluated in all patient samples using immunohistochemical staining with D2-40 and haematoxylin and eosin (H&E)-Victoria blue double staining, respectively. Clinicopathological and prognostic findings were classified by ly and v status, 66 (61.1%) were both ly (-) and v (-), invasion in ly and/or v were observed in 42 patients (38.9%); specifically, 7 ly (-) / v (+) (6.5%), 24 ly (+) / v (-) (22.2%), and 11 ly (+) / v (+) patients (10.2%), suggesting that deep stromal invasion and pelvic lymph node metastasis was significantly higher in the ly(+) and v (+) groups. Multiple logistic regression analysis of risk factor for local and distant recurrences identified FIGO stage IB2 or higher (odds ratio (OR); 6.437, p=0.0143) and v (OR; 9.290, p=0.0036) as independent risk factors for distant recurrence. In conclusion, we propose that by separately evaluating lymphatic and blood vessel invasions, useful information on prognosis about distant recurrence in cervical adenocarcinoma can be obtained. |
内容記述 |
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内容記述タイプ |
Other |
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内容記述 |
論文 |
出版者 |
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言語 |
ja |
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出版者 |
琉球医学会 |
出版者 |
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言語 |
en |
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出版者 |
Ryukyu Medical Association |
言語 |
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言語 |
eng |
資源タイプ |
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資源タイプ |
journal article |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
出版タイプ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
収録物識別子 |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
1346-888X |
収録物識別子 |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AN10369445 |
収録物名 |
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言語 |
ja |
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収録物名 |
琉球医学会誌 = Ryukyu Medical Journal |
書誌情報 |
巻 39,
号 1-4,
p. 21-28
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