Item type |
琉球大学リポジトリ登録用アイテムタイプ(1) |
公開日 |
2023-07-03 |
タイトル |
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タイトル |
Ability of suvorexant to prevent delirium in patients in the intensive care unit: a randomized controlled trial |
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言語 |
en |
作成者 |
Azuma, Kazunari
Takaesu, Yoshikazu
Soeda, Hiroshi
Iguchi, Aki
Uchida, Kotaro
Ohta, Shoichi
Mishima, Shiro
Inoue, Takeshi
Inoue, Yuichi
Oda, Jun
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アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
権利情報 |
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言語 |
en |
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権利情報 |
© 2018 The Authors. Acute Medicine & Surgery published by John Wiley & Sons Australia, Ltd on behalf of Japanese Association for Acute Medicine. |
権利情報 |
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言語 |
en |
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権利情報 |
This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
Delirium |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
intensive care unit |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
prevention |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
suvorexant |
内容記述 |
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内容記述タイプ |
Abstract |
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内容記述 |
Aim: There are no effective, tolerable, and established medications for preventing delirium in critically ill patients admitted to the intensive care unit (ICU). We investigated whether suvorexant was effective in preventing ICU delirium. Methods: This randomized controlled study evaluated 70 adult patients (age ≥20 years) admitted to the mixed medical ICU of the Tokyo Medical University Hospital (Tokyo, Japan) between May 2015 and February 2017. Patients were randomized using a sealed envelope method to receive either suvorexant (n = 34; 15 mg for elderly patients and 20 mg for younger adults) or conventional treatment (n = 36) for a 7-day period. The primary outcome was delirium incidence based on the definition in the 5th edition of the Diagnostic and Statistical Manual of Mental Disorders. Results: No significant between-group differences were observed in the demographic or clinical characteristics. Kaplan-Meier estimates revealed that time to delirium onset was significantly longer in the suvorexant group than in the conventional group (P < 0.05). Conclusion: Suvorexant might be effective in preventing delirium in ICU patients. |
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言語 |
en |
出版者 |
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言語 |
en |
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出版者 |
© 2018 The Authors. Acute Medicine & Surgery published by John Wiley & Sons Australia, Ltd on behalf of Japanese Association for Acute Medicine. |
言語 |
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言語 |
eng |
資源タイプ |
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資源タイプ |
journal article |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
出版タイプ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
関連情報 |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1002/ams2.368 |
収録物識別子 |
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収録物識別子タイプ |
EISSN |
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収録物識別子 |
2052-8817 |
収録物名 |
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言語 |
en |
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収録物名 |
Acute Medicine & Surgery |
書誌情報 |
巻 10,
号 1,
p. 362-368,
発行日 2018-08-19
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