| Item type |
琉球大学リポジトリ登録用アイテムタイプ(1) |
| 公開日 |
2023-07-18 |
| タイトル |
|
|
タイトル |
Effects of Japanese policies and novel hypnotics on long-term prescriptions of hypnotics |
|
言語 |
en |
| 作成者 |
Takeshima, Masahiro
Yoshizawa, Kazuhisa
Enomoto, Minori
Ogasawara, Masaya
Kudo, Mizuki
Itoh, Yu
Ayabe, Naoko
Takaesu, Yoshikazu
Mishima, Kazuo
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利情報 |
|
|
言語 |
en |
|
権利情報 |
© 2022 The Authors. Psychiatry and Clinical Neurosciences published by John Wiley & Sons Australia, Ltd on behalf of Japanese Society of Psychiatry and Neurology. |
| 権利情報 |
|
|
言語 |
en |
|
権利情報Resource |
https://creativecommons.org/licenses/by-nc/4.0/ |
|
権利情報 |
This is an open access article under the terms of the Creative Commons Attribution-NonCommercial License |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
benzodiazepine |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
hypnotic |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
insomnia |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
melatonin |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
orexin |
| 内容記述 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Aim: The current study aimed to examine the effect of Japanese policies for appropriate hypnotics use and novel hypnotics (e.g. melatonin receptor agonist and orexin receptor antagonist [ORA]) on long-term prescriptions of hypnotics.
Methods: This retrospective study was conducted using a large-scale health insurance claims database. Among subscribers prescribed hypnotics at least once between April 2005 and March 2021, those prescribed hypnotics for the first time after being included in the database in three periods (period 1: April 2012–March 2013; period 2: April 2016–March 2017; and period 3: April 2018–March 2019) were eligible. These were set considering the timing of the 2014 and 2018 medical fee revisions (2014 for polypharmacy of three or more hypnotics, 2018 for long-term prescription of benzodiazepine receptor agonists for >12 months). The duration of consecutive prescriptions of hypnotics over 12 months was evaluated. Factors associated with short-term prescriptions of hypnotics were also investigated.
Results: In total, 186 535 participants were newly prescribed hypnotics. The mean duration of prescriptions was 2.9 months, and 9.3% of participants were prescribed hypnotics for 12 months. Prescription periods were not associated with short-term prescriptions of hypnotics. ORA use was associated with short-term prescriptions of hypnotics (adjusted hazard ratio, 1.077 [95% confidence interval, 1.035–1.120]; P < 0.001), but melatonin receptor agonist use was not.
Conclusion: Japanese policies had no statistically significant effect on long-term prescriptions of hypnotics. Although this study suggests initiating ORA for insomniacs as a candidate strategy to prevent long-term prescriptions of hypnotics, further research is necessary to draw conclusions. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
© 2022 The Authors. Psychiatry and Clinical Neurosciences published by John Wiley & Sons Australia, Ltd on behalf of Japanese Society of Psychiatry and Neurology. |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 関連情報 |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.1111/pcn.13525 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
1440-1819 |
| 収録物名 |
|
|
収録物名 |
Psychiatry and Clinical Neurosciences |
|
言語 |
en |
| 書誌情報 |
巻 77,
号 5,
p. 264-272,
発行日 2022-12-29
|
T_No77p264.pdf (245 KB)
