| Item type |
琉球大学リポジトリ登録用アイテムタイプ(1) |
| 公開日 |
2023-09-06 |
| タイトル |
|
|
タイトル |
The Association of Smoking and Hyperuricemia with Renal Arteriolosclerosis in IgA Nephropathy |
|
言語 |
en |
| 作成者 |
Shinzato, Yuki
Zamami, Ryo
Oshiro, Nanako
Nakamura, Takuto
Ishida, Akio
Ohya, Yusuke
Kohagura, Kentaro
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利情報 |
|
|
言語 |
en |
|
権利情報 |
© 2023 by the authors. Licensee MDPI, Basel, Switzerland. |
| 権利情報 |
|
|
言語 |
en |
|
権利情報Resource |
https://creativecommons.org/licenses/by/4.0/ |
|
権利情報 |
This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
smoking |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
hyperuricemia |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
renal arteriolosclerosis |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
IgA nephropathy |
| 内容記述 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
The combination effects of smoking (SMK) and hyperuricemia (HU) on renal arteriolosclerosis in patients with IgA nephropathy remain unknown. We examined the cross-sectional association between smoking (current or former) and renal arteriolar hyalinosis and wall thickening with or without HU [uric acid (UA) level 7 and 5 mg/dL in men and women] in 87 patients with IgA nephropathy who underwent renal biopsy. Arteriolar hyalinosis and wall thickening were assessed by the semiquantitative grading of arterioles. The SMK/HU subgroup showed the highest indices for hyalinosis and wall thickening, followed by the non-SMK/HU, SMK/non-HU, and non- SMK/non-HU subgroups. Multiple logistic analysis showed that SMK/HU, but not SMK/non-HU, was significantly associated with an increased risk of higher-grade renal arteriolar wall thickening. However, this did not occur with hyalinosis compared to non-SMK/non-HU. The adjusted odds ratio (95% confidence interval, p value) for SMK/HU was 12.8 (1.36–119, p < 0.05) for wall thickening. An association between SMK and renal arteriolar wall thickening might be prevalent only among patients with HU and in patients with IgA nephropathy. Further prospective studies are needed to determine whether patients with HU and SMK history exhibit rapid eGFR deterioration. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
© 2023 by the authors. Licensee MDPI, Basel, Switzerland. |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 関連情報 |
|
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.3390/biomedicines11072053 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
2227-9059 |
| 収録物名 |
|
|
収録物名 |
Biomedicines |
|
言語 |
en |
| 書誌情報 |
巻 11,
号 7,
発行日 2023-07-21
|
S_No11p0.pdf (1.5 MB)
