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  1. 学術雑誌論文
  2. その他
  1. 部局別インデックス
  2. 医学部

The Association of Smoking and Hyperuricemia with Renal Arteriolosclerosis in IgA Nephropathy

http://hdl.handle.net/20.500.12000/0002020000
http://hdl.handle.net/20.500.12000/0002020000
33a72b5a-c550-48dd-a71b-6d1c8a7e4d67
名前 / ファイル ライセンス アクション
S_No11p0.pdf S_No11p0.pdf (1.5 MB)
Item type 琉球大学リポジトリ登録用アイテムタイプ(1)
公開日 2023-09-06
タイトル
タイトル The Association of Smoking and Hyperuricemia with Renal Arteriolosclerosis in IgA Nephropathy
言語 en
作成者 Shinzato, Yuki

× Shinzato, Yuki

en Shinzato, Yuki

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Zamami, Ryo

× Zamami, Ryo

en Zamami, Ryo

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Oshiro, Nanako

× Oshiro, Nanako

en Oshiro, Nanako

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Nakamura, Takuto

× Nakamura, Takuto

en Nakamura, Takuto

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Ishida, Akio

× Ishida, Akio

en Ishida, Akio

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Ohya, Yusuke

× Ohya, Yusuke

en Ohya, Yusuke

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Kohagura, Kentaro

× Kohagura, Kentaro

en Kohagura, Kentaro

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アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利情報
言語 en
権利情報 © 2023 by the authors. Licensee MDPI, Basel, Switzerland.
権利情報
言語 en
権利情報Resource https://creativecommons.org/licenses/by/4.0/
権利情報 This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license
主題
言語 en
主題Scheme Other
主題 smoking
主題
言語 en
主題Scheme Other
主題 hyperuricemia
主題
言語 en
主題Scheme Other
主題 renal arteriolosclerosis
主題
言語 en
主題Scheme Other
主題 IgA nephropathy
内容記述
内容記述タイプ Abstract
内容記述 The combination effects of smoking (SMK) and hyperuricemia (HU) on renal arteriolosclerosis in patients with IgA nephropathy remain unknown. We examined the cross-sectional association between smoking (current or former) and renal arteriolar hyalinosis and wall thickening with or without HU [uric acid (UA) level 7 and 5 mg/dL in men and women] in 87 patients with IgA nephropathy who underwent renal biopsy. Arteriolar hyalinosis and wall thickening were assessed by the semiquantitative grading of arterioles. The SMK/HU subgroup showed the highest indices for hyalinosis and wall thickening, followed by the non-SMK/HU, SMK/non-HU, and non- SMK/non-HU subgroups. Multiple logistic analysis showed that SMK/HU, but not SMK/non-HU, was significantly associated with an increased risk of higher-grade renal arteriolar wall thickening. However, this did not occur with hyalinosis compared to non-SMK/non-HU. The adjusted odds ratio (95% confidence interval, p value) for SMK/HU was 12.8 (1.36–119, p < 0.05) for wall thickening. An association between SMK and renal arteriolar wall thickening might be prevalent only among patients with HU and in patients with IgA nephropathy. Further prospective studies are needed to determine whether patients with HU and SMK history exhibit rapid eGFR deterioration.
言語 en
出版者
言語 en
出版者 © 2023 by the authors. Licensee MDPI, Basel, Switzerland.
言語
言語 eng
資源タイプ
資源タイプ journal article
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
関連情報
識別子タイプ DOI
関連識別子 https://doi.org/10.3390/biomedicines11072053
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 2227-9059
収録物名
言語 en
収録物名 Biomedicines
書誌情報
巻 11, 号 7, 発行日 2023-07-21
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