| Item type |
琉球大学リポジトリ登録用アイテムタイプ(1) |
| 公開日 |
2023-12-05 |
| タイトル |
|
|
タイトル |
Clinically amyopathic dermatomyositis manifested after the allogeneic haematopoietic stem cell transplantation: Case presentation and literature review |
|
言語 |
en |
| 作成者 |
Miyagi, Riko
Nakachi, Sawako
Tamaki, Yasutaro
Doi, Mototsugu
Nakajima, Tomo
Tomori, Shohei
Hanashiro, Taeko
Tamaki, Keita
Morichika, Kazuho
Nishi, Yukiko
Morishima, Satoko
Fukushima, Takuya
Masuzaki, Hiroaki
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利情報 |
|
|
言語 |
en |
|
権利情報 |
© Japan College of Rheumatology 2022. Published by Oxford University Press. |
| 権利情報 |
|
|
言語 |
en |
|
権利情報Resource |
https://creativecommons.org/licenses/by-nc/4.0/ |
|
権利情報 |
This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Interstitial lung disease |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
clinically amyopathic dermatomyositis |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
anti-MDA-5 antibody |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
chronic graft versus host disease (GvHD) |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
allogeneic haematopoietic stem cell transplantation (allo-HSCT) |
| 内容記述 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Clinically amyopathic dermatomyositis (CADM) lacks muscle symptoms, associated with rapidly progressive interstitial lung disease. Anti-melanoma differentiation-associated gene 5 (MDA-5) antibody has been identified as a disease-labelling autoantibody. We report two cases of CADM manifested after the allogeneic haematopoietic stem cell transplantation (allo-HSCT)—Case 1: a 56-year-old man with acute leukaemia received the allo-HSCT and Case 2: a 45-year-old female patient with lymphoma received the allo-HSCT. She received donor lymphocyte infusion because of a post-transplant relapse. After allo-HSCT or donor lymphocyte infusion, Gottron papules emerged, and both patients were diagnosed as CADM based on dermatological findings coupled with the positivity of anti-MDA-5 antibody, accompanied by interstitial shadows consistent with ILD on chest computed tomography. Case 2 was initially diagnosed as a kind of chronic graft versus host disease. Their symptoms were improved by the combination of immunosuppressive agents with a concomitant decrease in anti-MDA-5 antibody levels. For Case 2, rituximab was subsequently started for relapse of lymphoma, resulting in a substantial decrease in the level of anti-MDA-5 antibody and improvement in rash and ILD. Our cases raise a possibility that CADM emerges after the HSCT, highlighting the importance of early diagnosis to avoid fated progression into ILD. |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
Oxford University Press |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 識別子 |
|
|
識別子 |
https://doi.org/10.1093/mrcr/rxac060 |
|
識別子タイプ |
DOI |
| 収録物識別子 |
|
|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
2472-5625 |
| 収録物名 |
|
|
収録物名 |
Modern Rheumatology Case Reports |
|
言語 |
en |
| 書誌情報 |
巻 7,
号 1,
p. 102-107,
発行日 2022-08-11
|
M_No7p102.pdf (1.5 MB)
