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  1. 紀要論文
  2. 琉球大学教育学部紀要
  3. 34号
  1. 部局別インデックス
  2. 教育学部

A STUDY ON THE QUATERNARY STRUCTURE CHANGE OF HEMOGLOBIN I. INTERMEDIATE STRUCTURES IN O_2 LIGATION PROCESS

http://hdl.handle.net/20.500.12000/1873
http://hdl.handle.net/20.500.12000/1873
9ee5868a-d058-4780-baba-b4b09d89bc97
名前 / ファイル ライセンス アクション
Vol34p247.pdf Vol34p247.pdf
Item type デフォルトアイテムタイプ(フル)(1)
公開日 2007-09-15
タイトル
タイトル A STUDY ON THE QUATERNARY STRUCTURE CHANGE OF HEMOGLOBIN I. INTERMEDIATE STRUCTURES IN O_2 LIGATION PROCESS
言語 en
作成者 Arata, Yasuhide

× Arata, Yasuhide

en Arata, Yasuhide

Yara, Asao

× Yara, Asao

en Yara, Asao

新田, 保秀

× 新田, 保秀

ja 新田, 保秀

屋良, 朝夫

× 屋良, 朝夫

ja 屋良, 朝夫

アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
内容記述
内容記述タイプ Other
内容記述 Conformational interaction at the interfaces between subunits are investigated on the basis of the atomic coordinates of human deoxy and human oxy Hbs. Hypothetical intermediate structures are used, each of which is obtained from the procedure where one or more subunits in deoxy Hb are replaced by the corresponding O_2-liganded subunits in oxy Hb using the method of superimposition of two sets of atomic coordinates. When either α or β subunit is substituted with the corresponding subunit in oxy Hb, serious steric hindrances are produced between α_1FG 4(92)Arg and β_2C 3(37)Trp or between α_1C 6(41)Thr and β_2FG 4(97)His, all of which belong to the allosteric core affected directly by ligand binding. These steric hindrances become more serious when both α_1(α_2) and β_2 (β_1) subunits are substituted. However, no steric hindrance can be seen between subunits when the subunits in oxy Hb are substituted with the corresponding subunits in deoxy Hb.
内容記述タイプ Other
内容記述 紀要論文
出版者
言語 ja
出版者 琉球大学教育学部
言語
言語 eng
資源タイプ
資源タイプ departmental bulletin paper
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
識別子
識別子 http://hdl.handle.net/20.500.12000/1873
識別子タイプ HDL
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 0386-5746
収録物識別子タイプ NCID
収録物識別子 AN10144831
収録物名
言語 ja
収録物名 琉球大学教育学部紀要 第一部・第二部
書誌情報
号 34, p. 247-257
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