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  1. 紀要論文
  2. 琉球大学農学部学術報告
  3. 50号
  1. 部局別インデックス
  2. 農学部

食餌制限したラットで誘発する骨粗鬆症

http://hdl.handle.net/20.500.12000/3609
http://hdl.handle.net/20.500.12000/3609
740833d7-007e-4281-b573-bfbf064d410c
名前 / ファイル ライセンス アクション
KJ00004258147.pdf KJ00004258147.pdf
Item type デフォルトアイテムタイプ(フル)(1)
公開日 2008-02-14
タイトル
タイトル 食餌制限したラットで誘発する骨粗鬆症
言語 ja
作成者 ?, ?曼

× ?, ?曼

ja ?, ?曼

石丸, 哲二

× 石丸, 哲二

ja 石丸, 哲二

玉城, 一

× 玉城, 一

ja 玉城, 一

知念, 功

× 知念, 功

ja 知念, 功

Sun, Liman

× Sun, Liman

en Sun, Liman

Ishimaru, Tetsuji

× Ishimaru, Tetsuji

en Ishimaru, Tetsuji

Tamaki, Hajime

× Tamaki, Hajime

en Tamaki, Hajime

Chinen, Isao

× Chinen, Isao

en Chinen, Isao

アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
主題
言語 ja
主題Scheme Other
主題 骨粗鬆症
言語 ja
主題Scheme Other
主題 食餌制限
言語 ja
主題Scheme Other
主題 女性ホルモン
言語 ja
主題Scheme Other
主題 骨密度
内容記述
内容記述タイプ Other
内容記述 6週齢のWistar系雌ラットにAIN-93G標準食を自由摂食させながら1週間予備飼育した後,自由食群と食餌制限群に分けた。自由食群は標準食を自由摂取させた。食餌制限群は標準食群,標準食中のタンパク質を2倍にした群,ビタミンとミネラルを2倍にした群,脂肪を2倍にした群,ビタミン,ミネラル,タンパク質を2倍にした群の5群をつくって3週間50%食餌制限し,大腿骨の破断エネルギー等を調べ,骨粗鬆症を誘発するか研究した。1. 3週間の食餌制限でラットの体重は約10g減少した。自由食群では約35g増加した。2.食餌制限群の骨の長さが有意に短くなった。3.大腿骨の骨塩量,骨密度,骨破断エネルギーはどタミン,ミネラルが所要量みたしている群も含め,すべての食餌制限群で有意に減少したが,X線透過濃度は逆に有意に高くなり,7週齢の雌ラットを3週間50%食餌制限すると骨粗鬆症を誘発した。4.子宮の重量は,食餌制限すると有意に減少した。このことは,食餌制限により誘発した骨粗鬆症は子宮が小さくなり,エストロゲンが欠乏し,誘発したと推察された。
内容記述タイプ Other
内容記述 Six-weeks-old female Wister strain rats were kept on standard feed prepared according to AIN-93G for 1 week before commencing the experiment. Then, the animals were divided into control group (group 1) fed ad libitum standard feed and 5 groups (group 2-6) of a diets as it is, doubled protein, mineral and vitamin, fat, and mineral, vitamin and protein, respectively maintained under 50% diet for 3 weeks. One group contained 5 rats. Breaking power of the femur, bone density and density of X-ray picture were examined to check introduction of osteoporosis by diet. 1. Body weight dropped about 10g for 3 weeks by a diet of 50%. 2. Length of bone were significantly short at all restricted groups. 3. Bone density, mineral content and breaking power notably decreased in all diet groups, but density of picture of X-ray raised. Dieting by 50% percent diet of seven weeks age female rat for three weeks certainly caused osteoporosis. 4. Weight of a uterine significantly declined at diet group, osteoporosis bringing about by a diet suggests due to a lack of estrogen from reduction of a womb by it.
内容記述タイプ Other
内容記述 紀要論文
出版者
言語 ja
出版者 琉球大学農学部
言語
言語 jpn
資源タイプ
資源タイプ departmental bulletin paper
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
識別子
識別子 http://hdl.handle.net/20.500.12000/3609
識別子タイプ HDL
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 0370-4246
収録物識別子タイプ NCID
収録物識別子 AN00250548
収録物名
言語 ja
収録物名 琉球大学農学部学術報告
書誌情報
号 50, p. 157-163
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