{"_buckets": {"deposit": "0008de9e-2c55-4f2f-b897-34d1b8e08393"}, "_deposit": {"id": "2011336", "owners": [1], "pid": {"revision_id": 0, "type": "depid", "value": "2011336"}, "status": "published"}, "_oai": {"id": "oai:u-ryukyu.repo.nii.ac.jp:02011336", "sets": ["1642838338003", "1642838407795"]}, "author_link": [], "item_1617186331708": {"attribute_name": "Title", "attribute_value_mlt": [{"subitem_1551255647225": "強皮症様皮膚硬化を認める難治性慢性GVHDに対し短波長紫外線照射が奏功した4症例", "subitem_1551255648112": "ja"}, {"subitem_1551255647225": "Efficacy of narrowband UV-B phototherapy for pediatric restrictive sclerodermatous chronic graft-versus host dsease (GVHD) : a report of 4 cases from a single institute", "subitem_1551255648112": "en"}]}, "item_1617186419668": {"attribute_name": "Creator", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "浜田, 聡", "creatorNameLang": "ja"}]}, {"creatorNames": [{"creatorName": "宮下, 倫江", "creatorNameLang": "ja"}]}, {"creatorNames": [{"creatorName": "山本, 雄一", "creatorNameLang": "ja"}]}, {"creatorNames": [{"creatorName": "宮本, 二郎", "creatorNameLang": "ja"}]}, {"creatorNames": [{"creatorName": "屋冝, 孟", "creatorNameLang": "ja"}]}, {"creatorNames": [{"creatorName": "大城, 登喜子", "creatorNameLang": "ja"}]}, {"creatorNames": [{"creatorName": "浜田, 有為子", "creatorNameLang": "ja"}]}, {"creatorNames": [{"creatorName": "喜友名, しのぶ", "creatorNameLang": "ja"}]}, {"creatorNames": [{"creatorName": "新垣, 真弓", "creatorNameLang": "ja"}]}, {"creatorNames": [{"creatorName": "百名, 伸之", "creatorNameLang": "ja"}]}, {"creatorNames": [{"creatorName": "Hamada, Satoru", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Miyashita, Michie", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Yamamoto, Yuichi", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Miyamoto, Jiro", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Yagi, Takeshi", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Oshiro, Tokiko", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Hamada, Yuiko", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Kiyuna, Shinobu", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Arakaki, Mayumi", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Hyakuna, Nobuyuki", "creatorNameLang": "en"}]}]}, "item_1617186476635": {"attribute_name": "Access Rights", "attribute_value_mlt": [{"subitem_1522299639480": "open access", "subitem_1600958577026": "http://purl.org/coar/access_right/c_abf2"}]}, "item_1617186499011": {"attribute_name": "Rights", "attribute_value_mlt": [{"subitem_1522650717957": "ja", "subitem_1522651041219": "© 2016 日本小児血液・がん学会"}]}, "item_1617186609386": {"attribute_name": "Subject", "attribute_value_mlt": [{"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "sclerodermatous graft-versus-host disease"}, {"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "narrowband UV-B"}, {"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "joint contracture"}]}, "item_1617186626617": {"attribute_name": "Description", "attribute_value_mlt": [{"subitem_description": "Sclerodermatous GVHD is a late effect of hematopoietic stem cell transplantation, which results in the impairment of the quality of a survivor’s life, and is difficult to manage. Most cases are often steroid-refractory and steroid-dependent sclerodermatous GVHD, and secondary treatment sometimes has limited efficacy. We performed a retrospective study on four sclerodermatous GVHD patients presenting severe joint contracture treated with narrow-band ultraviolet B (NB-UVB) from July 2012 to May 2015. All the patients had sclerodermatous grade 2 or higher according to the National Institutes of Health (NIH) grading, and showed less than 70% in the performance scale (PS). Three patients received steroid therapy, namely, two patients with steroid-refractory and one patient with steroiddependent sclerodermatous GVHD. The remaining patient had a high possibility of acute myeloid leukemia relapse, favoring less immunosuppressant administration. We evaluated the responses of the patients with a photographic range of motion according to the NIH therapeutic response criteria. The observation period after irradiation was 718 days (range: 368–1039 days). A mean cumulative dose of 75 J/cm^2 (range: 51–221 J/cm^2 ) was applied in a mean number of 69 irradiations (range 53–159). All the patients showed improvement in the range of motion. The PS score was improved from a mean of 40% (pretreatment) to 75% (post-treatment). In western countries, extracorporeal photopheresis (ECP) is the mainstream secondary treatment for sclerodermatous GVHD, and its clinical trial is in progress in Japan. ECP is a promising treatment; however, there are a few problems, such as its high cost and facility accessibility in local areas. Therefore, NB-UVB can be an encouraging alternative to ECP for sclerodermatous GVHD.", "subitem_description_type": "Other"}, {"subitem_description": "論文", "subitem_description_type": "Other"}]}, "item_1617186643794": {"attribute_name": "Publisher", "attribute_value_mlt": [{"subitem_1522300295150": "ja", "subitem_1522300316516": "日本小児血液・がん学会"}]}, "item_1617186702042": {"attribute_name": "Language", "attribute_value_mlt": [{"subitem_1551255818386": "jpn"}]}, "item_1617186783814": {"attribute_name": "Identifier", "attribute_value_mlt": [{"subitem_identifier_type": "HDL", "subitem_identifier_uri": "http://hdl.handle.net/20.500.12000/47686"}]}, "item_1617186920753": {"attribute_name": "Source Identifier", "attribute_value_mlt": [{"subitem_1522646500366": "ISSN", "subitem_1522646572813": "2189-5384"}, {"subitem_1522646500366": "ISSN", "subitem_1522646572813": "2187-011X"}]}, "item_1617186941041": {"attribute_name": "Source Title", "attribute_value_mlt": [{"subitem_1522650068558": "ja", "subitem_1522650091861": "日本小児血液・がん学会雑誌"}]}, "item_1617187056579": {"attribute_name": "Bibliographic Information", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2016", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "5", "bibliographicPageEnd": "458", "bibliographicPageStart": "453", "bibliographicVolumeNumber": "53"}]}, "item_1617258105262": {"attribute_name": "Resource Type", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_1617265215918": {"attribute_name": "Version Type", "attribute_value_mlt": [{"subitem_1522305645492": "VoR", "subitem_1600292170262": "http://purl.org/coar/version/c_970fb48d4fbd8a85"}]}, "item_1617353299429": {"attribute_name": "Relation", "attribute_value_mlt": [{"subitem_1522306287251": {"subitem_1522306382014": "DOI", "subitem_1522306436033": "https://doi.org/10.11412/jspho.53.453"}}, {"subitem_1522306287251": {"subitem_1522306382014": "DOI", "subitem_1522306436033": "https://doi.org/10.11412/jspho.53.453"}}]}, "item_1617605131499": {"attribute_name": "File", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_access", "download_preview_message": "", "file_order": 0, "filename": "53_453.pdf", "future_date_message": "", "is_thumbnail": false, "mimetype": "", "size": 0, "url": {"objectType": "fulltext", "url": "https://u-ryukyu.repo.nii.ac.jp/record/2011336/files/53_453.pdf"}, "version_id": "49732e69-6edb-4482-b4aa-ee27ba5923de"}]}, "item_title": "強皮症様皮膚硬化を認める難治性慢性GVHDに対し短波長紫外線照射が奏功した4症例", "item_type_id": "15", "owner": "1", "path": ["1642838338003", "1642838407795"], "permalink_uri": "http://hdl.handle.net/20.500.12000/47686", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2021-01-29"}, "publish_date": "2021-01-29", "publish_status": "0", "recid": "2011336", "relation": {}, "relation_version_is_last": true, "title": ["強皮症様皮膚硬化を認める難治性慢性GVHDに対し短波長紫外線照射が奏功した4症例"], "weko_shared_id": -1}
強皮症様皮膚硬化を認める難治性慢性GVHDに対し短波長紫外線照射が奏功した4症例
http://hdl.handle.net/20.500.12000/47686
http://hdl.handle.net/20.500.12000/47686