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  1. 学術雑誌論文
  2. 琉球医学会
  3. 琉球医学会誌
  4. 25巻1・2号
  1. 部局別インデックス
  2. その他

[原著]A Prospective Trial of Oral Betamethason and Oral Lorazepam in the Management of Delayed Nausea and Vomiting Induced by Cisplatin-Based Chemotherapy

http://hdl.handle.net/20.500.12000/0002015603
http://hdl.handle.net/20.500.12000/0002015603
64550906-e390-4886-bc3f-3dd179b99220
名前 / ファイル ライセンス アクション
v25p17.pdf v25p17.pdf
Item type デフォルトアイテムタイプ(フル)(1)
公開日 2010-02-23
タイトル
タイトル [原著]A Prospective Trial of Oral Betamethason and Oral Lorazepam in the Management of Delayed Nausea and Vomiting Induced by Cisplatin-Based Chemotherapy
言語 ja
作成者 Uehara, Tadashi

× Uehara, Tadashi

en Uehara, Tadashi

Yohena, Tomofumi

× Yohena, Tomofumi

en Yohena, Tomofumi

Kanematsu, Takanori

× Kanematsu, Takanori

en Kanematsu, Takanori

Teruya, Takao

× Teruya, Takao

en Teruya, Takao

Ikeda, Jiro

× Ikeda, Jiro

en Ikeda, Jiro

Okamoto, Junichi

× Okamoto, Junichi

en Okamoto, Junichi

Asoh, Hiroshi

× Asoh, Hiroshi

en Asoh, Hiroshi

Ichinose, Yukito

× Ichinose, Yukito

en Ichinose, Yukito

アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利情報
言語 ja
権利情報 琉球医学会
主題
言語 en
主題Scheme Other
主題 Betamethason
言語 en
主題Scheme Other
主題 Chemotherapy
言語 en
主題Scheme Other
主題 Cisplatm
言語 en
主題Scheme Other
主題 Delayed emesis
言語 en
主題Scheme Other
主題 Lorazepam
言語 en
主題Scheme Other
主題 Lung Cancer
内容記述
内容記述タイプ Other
内容記述 Purpose: The optimal treatment modality for delayed emesis occurring later than 24 hours after the administration of cisplatin-based chemotherapy has not yet been established. Patients and Methods: Twenty patients received 5-hydroxytryptamine 3 receptor antagonist intravenously for the treatment of acute emesis just before cisplatm infusion in the first cycle of treatment, and the thereafter they received oral administration of betamethason ($\2mgtimes3/day$) plus oral lorazepam ($\0.5mgtimes3/day$) for 5 days in trial I. In trial II, 14 patients who received the other anti-emetic regimen (methylprednisolone plus metoclopramide) for delayed emesis in the first cycle of chemotherapy were treated by this regimen for the second cycle of treatment. A complete response (CR) was defined as no emetic episodes and a partial response (PR) as no vomiting episodes but some nausea. The effects of anti-emetic treatments were evaluated for 5 days from the next day after cisplatin administration. Results: The mean control rate (percentage of CR+PR) and CR rate for delayed emesis for the 5-day period were 97% and 84%, respectively in trial I. The mean control rate in patients undergoing the other anti-emetic regimen in the first cycle of chemotherapy was 60% compared to 96% in the same patients undergoing this regimen in the second cycle of the same chemotherapy in trial II. Conclusions: Oral betamethason plus lorazepam demonstrated a high control rate for delayed nausea and vomiting induced by cisplatin-based chemotherapy.
内容記述タイプ Other
内容記述 論文
出版者
言語 ja
出版者 琉球医学会
言語
言語 eng
資源タイプ
資源タイプ journal article
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 1346-888X
収録物識別子タイプ ISSN
収録物識別子 0289-1530
収録物識別子タイプ NCID
収録物識別子 AN10369445
収録物名
言語 ja
収録物名 琉球医学会誌 = Ryukyu Medical Journal
書誌情報
巻 25, 号 1・2, p. 17-22
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