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[総説]HTLV-1関連脊髄症の病態と病因 : 宿主因子・ウイルス因子の相互作用と発症への関与
http://hdl.handle.net/20.500.12000/0002015623
http://hdl.handle.net/20.500.12000/000201562342c6cc92-a5bf-4c4e-b5d4-e7f2e6669bae
名前 / ファイル | ライセンス | アクション | |
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Item type | デフォルトアイテムタイプ(フル)(1) | |||||||||
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公開日 | 2010-04-28 | |||||||||
タイトル | ||||||||||
タイトル | [総説]HTLV-1関連脊髄症の病態と病因 : 宿主因子・ウイルス因子の相互作用と発症への関与 | |||||||||
言語 | ja | |||||||||
作成者 |
斎藤, 峰輝
× 斎藤, 峰輝
× Saito, Mineki
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アクセス権 | ||||||||||
アクセス権 | open access | |||||||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||
権利情報 | ||||||||||
言語 | ja | |||||||||
権利情報 | 琉球医学会 | |||||||||
主題 | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | HTLV-1 | |||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | HAM/TSP | |||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | HLA | |||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | immune response | |||||||||
内容記述 | ||||||||||
内容記述タイプ | Other | |||||||||
内容記述 | Human T-cell lymphotropic virus type 1 (HTLV-1)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is a chronic progressive myelopathy characterized by spastic paraparesis and sphincter dysfunction observed in a minority of HTLV-1 infected individuals. Previously studies indicated that HTLV-1 Tax subtype, several HLA and non-HLA genes are closely associated with the development of HAM/TSP. Two HAM/TSP associated alleles, HLA-A^*02 and HLA-DRB1^*0101 can recognize immunodominant HTLV-1 epitopes, and some HAM/TSP associated non-HLA genes are trans-activated by HTLV-1 Tax protein. Namely, complex virus-host interactions play an important role in determining the risk of HAM/TSP. | |||||||||
内容記述タイプ | Other | |||||||||
内容記述 | 論文 | |||||||||
出版者 | ||||||||||
言語 | ja | |||||||||
出版者 | 琉球医学会 | |||||||||
言語 | ||||||||||
言語 | jpn | |||||||||
資源タイプ | ||||||||||
資源タイプ | journal article | |||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
出版タイプ | ||||||||||
出版タイプ | VoR | |||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||
収録物識別子 | ||||||||||
収録物識別子タイプ | ISSN | |||||||||
収録物識別子 | 1346-888X | |||||||||
収録物識別子タイプ | ISSN | |||||||||
収録物識別子 | 0289-1530 | |||||||||
収録物識別子タイプ | NCID | |||||||||
収録物識別子 | AN10369445 | |||||||||
収録物名 | ||||||||||
言語 | ja | |||||||||
収録物名 | 琉球医学会誌 = Ryukyu Medical Journal | |||||||||
書誌情報 |
巻 28, 号 1・2, p. 1-7 |