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  1. 学術雑誌論文
  2. 琉球医学会
  3. 琉球大学医学会雑誌
  4. 9巻2号
  1. 部局別インデックス
  2. その他

[原著]Effects of Some Anti-Anginal Drugson Ergonovine-Induced Contractions of Isolated Dog Coronary Arteries

http://hdl.handle.net/20.500.12000/0002015727
http://hdl.handle.net/20.500.12000/0002015727
73b40f2e-b88c-4422-a2d4-45d72e0aab1e
名前 / ファイル ライセンス アクション
v9p81.pdf v9p81.pdf
Item type デフォルトアイテムタイプ(フル)(1)
公開日 2010-06-30
タイトル
タイトル [原著]Effects of Some Anti-Anginal Drugson Ergonovine-Induced Contractions of Isolated Dog Coronary Arteries
言語 ja
作成者 Sakanashi, Matao

× Sakanashi, Matao

en Sakanashi, Matao

Ito, Hirosumi

× Ito, Hirosumi

en Ito, Hirosumi

Noguchi, Katsuhiko

× Noguchi, Katsuhiko

en Noguchi, Katsuhiko

Nagamine, Fumio

× Nagamine, Fumio

en Nagamine, Fumio

アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利情報
言語 ja
権利情報 琉球医学会
主題
言語 en
主題Scheme Other
主題 Dog coronary artery
言語 en
主題Scheme Other
主題 Ergonovine
言語 en
主題Scheme Other
主題 Contraction
言語 en
主題Scheme Other
主題 Alpha adrenoceptor
言語 en
主題Scheme Other
主題 Anti-anginal drug
内容記述
内容記述タイプ Other
内容記述 Effects of some anti-anginal drugs on dog coronary arterial contractions induced by ergonovine were investigated in vitro under potassium-contracture. Administrations of phentolamine (10^<-6>g/ml) or phenoxybenzamine (3x1O^<-6>g/ml) did not affect potassium-contracture and ergonovine (10^<-6>g/ml)-induced contractions of coronary arterial strips, but phentolamine at a higher dose (10^<-5>g/ml) depressed both of them. Dihydroergotamine (10^<-7> -10^<-6>g/ml) produced further contractions of the strips under potassium-contracture and dose-dependently depressed ergonovine-induced contractions. Contractile responses to ergonovine (10^<-6>g/ml) were depressed by prior administrations of nitroglycerin (10^<-7>-10^<-6>g/ml), nifedipine (10^<-8>-10^<-7>g/ml), diltiazem(10^<-6>-10^<-5>g/ml) and SG-75 (10^<-6>-10^<-5>g/ml)in a dose-dependent fashion. Results indicate that ergonovine-induced contractions of isolated dog coronary arteries under potassium-contracture are not mediated mainly through an activation of alpha adrenoceptors and that some anti-anginal drugs such as nitroglycerin, nifedipine, diltiazem and SG-75 have a depressant action on these contractions.
内容記述タイプ Other
内容記述 論文
出版者
言語 ja
出版者 琉球大学医学部
言語
言語 eng
資源タイプ
資源タイプ journal article
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 0289-1530
収録物識別子タイプ NCID
収録物識別子 AN10027430
収録物名
言語 ja
収録物名 琉球大学医学会雑誌 : 医学部紀要 = Ryukyu medical journal
書誌情報
巻 9, 号 2, p. 81-88
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