Item type |
デフォルトアイテムタイプ(フル)(1) |
公開日 |
2010-06-30 |
タイトル |
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タイトル |
[症例報告]皮膚結節及び末棺血より ATL virus を確認した chronic ATL の1例 |
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言語 |
ja |
タイトル |
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タイトル |
A case of chronic ATL (Adult T-cell Leukemia) which was detected ATL virus from skin nodules and peripheral lymphocytes |
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言語 |
en |
作成者 |
上里, 博
宮里, 肇
真栄平, 房裕
佐野, 幸仁
細川, 篤
伊集, 操
照屋, 智
名嘉真, 武男
新里, 脩
荒木, 弘一
斎藤, 義雄
Uesato, Hiroshi
Miyazato, Hajime
Maehira, Fusahiro
Sano, Yukihito
Hosokawa, Atsushi
Iju, Misao
Teruya, Satoshi
Nakama, Takeo
Shinzato, Osamu
Araki, Kooicho
Saito, Yoshio
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アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
権利情報 |
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言語 |
ja |
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権利情報 |
琉球医学会 |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
choronic ATL |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
ATL virus |
主題 |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
helper T cell |
内容記述 |
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内容記述タイプ |
Other |
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内容記述 |
A case of chronic ATL of 61-year old male was discussed, who had papules and nodules of various sizes on the skin without having generalized signs and symptoms for about 11 years. Histopathological examinations disclosed Pautrier's microabscess in the epidermis and band-like or patchy infiltration of abnormal lymphocytes to upper and middle dermis of the papules, but the former was not observed in the epidermis of the nodules , the latter was observed among whole dermis of the nodules. Almost all of abnormal lymphocytes were positive for Leu 1, Leu 4 and Leu 3a, and monoclonal proliferatipn of lymphocytes with the surface marker of helper T cells was noted in the immunohistological studies by modified immunoperoxidase method (ABC method ). Leukocytosis with abnormal lymphocytes (known as flower cell) were observed in the peripheral blood. The anti-ATLA antibody was as low as 10 times, while the leveles of lmmunoglobulins were high. Peripheral lymphocytes and skin infiltrating single cell cells had not only the surface property of helper T cell, but also the reactivity with GIN 14 (monoclonal antibody against P19 and p28 of ATL virus) when 7-day cultured cells were tested by indirect immunofluorescent antibody method. Among the family, anti-ATLA antibody positive individuals were noted with high ratio of 57%. Treatment with predonisolone gave a good control of peripheral abnormal lymphocytes and skin lesions. |
内容記述 |
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内容記述タイプ |
Other |
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内容記述 |
論文 |
出版者 |
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言語 |
ja |
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出版者 |
琉球大学医学部 |
出版者 |
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言語 |
en |
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出版者 |
Faculty of Medicine, University of the Ryukyus |
言語 |
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言語 |
jpn |
資源タイプ |
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資源タイプ |
journal article |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
出版タイプ |
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出版タイプ |
VoR |
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出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
収録物識別子 |
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収録物識別子タイプ |
ISSN |
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収録物識別子 |
0289-1530 |
収録物識別子 |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AN10027430 |
収録物名 |
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言語 |
ja |
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収録物名 |
琉球大学医学会雑誌 : 医学部紀要 = Ryukyu medical journal |
書誌情報 |
巻 8,
号 1,
p. 40-52,
発行日 1985
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