| Item type |
デフォルトアイテムタイプ（フル）(1) |
| 公開日 |
2010-06-30 |
| タイトル |
|
|
タイトル |
[症例報告]下垂体腫瘤を形成した原発性甲状腺機能低下症の1治験例 |
|
言語 |
ja |
| タイトル |
|
|
タイトル |
A Case of Primary Hypothyroidism Presenting with Pituitary Enlargement |
|
言語 |
en |
| 作成者 |
佐久田, 治
六川, 二郎
高良, 英一
中田, 宗朝
金城, 利彦
外間, 朝哲
Sakuta, Osamu
Mukawa, Jiro
Takara, Eiichi
Nakata, Munetomo
Kinjo, Toshihiko
Hokama, Asanori
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利情報 |
|
|
言語 |
ja |
|
権利情報 |
琉球医学会 |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
hypothyroidism |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
pituitary tumor |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
hyperplasia |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
magnetic resonance imaging(MRI) |
| 内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
A 36-year-old woman suffered from headache and swelling of the face and limbs. Neurological examination revealed mild weakness and a prolonged relaxation phase of deep tendon reflexes. MRI(T1 weighted images : SE 500/30) showed pituitary enlargement extending to supraseller region. Serum T3 and T4 were low, and TSH was abnormally high. In anterior pituitary hormone assessment test, there was a notable increase in both TSH and prolactin concentrations by the administration of TRH. Thyroid replacement therapy was programmed without surgery, and the pituitary gland was checked by MRI. Within 3 months after the therapy serum T3 and T4 were normalized and TSH level was reduced. The pituitary gland was reduced in size from 17×10×18mm to 7 ×10×10mm measured by MRI. Characteristic MRI findings of our case was a round high intensity mass in the midline of the pituitary region in T1 weighted images(SE 500/30). Only 8 cases of pituitary regression by thyroid replacement therapy were reported in the literature. They were considered to be pituitary hyperplasia, rather than pituitary adenoma, caused by longstanding untreated hypothyroidism. Pituitary hyperplasia with hipothyroidism tend to be mistaken for pituitary adenoma, although endocrinological examination may be ruled it out. The first choice of the treatment for this type of pituitary mass should be thyroid replacement therapy unless the patient has a severe visual disturbance. If there is no regression of pituitary mass, then diagnosis is to be adenoma and surgery should be indicated. |
| 内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
論文 |
| 出版者 |
|
|
出版者 |
琉球大学医学部 |
|
言語 |
ja |
| 出版者 |
|
|
出版者 |
Faculty of Medicine, University of the Ryukyus |
|
言語 |
en |
| 言語 |
|
|
言語 |
jpn |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0289-1530 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AN10027430 |
| 収録物名 |
|
|
収録物名 |
琉球大学医学会雑誌 : 医学部紀要 = Ryukyu medical journal |
|
言語 |
ja |
| 書誌情報 |
巻 10,
号 3-4,
p. 180-184,
発行日 1988
|
v10p180.pdf
