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  1. 学術雑誌論文
  2. 琉球医学会
  3. 琉球医学会誌
  4. 18巻1-2号
  1. 部局別インデックス
  2. その他

[総説]排卵への蛋白分解酵素の役割 : (2)コラーゲン分解系の役割

http://hdl.handle.net/20.500.12000/0002016039
http://hdl.handle.net/20.500.12000/0002016039
54e09286-590d-4a8b-b33a-828d9a475681
名前 / ファイル ライセンス アクション
v18p11.pdf v18p11.pdf
Item type デフォルトアイテムタイプ(フル)(1)
公開日 2010-07-02
タイトル
タイトル [総説]排卵への蛋白分解酵素の役割 : (2)コラーゲン分解系の役割
言語 ja
作成者 小杉, 忠誠

× 小杉, 忠誠

ja 小杉, 忠誠

砂川, 昌範

× 砂川, 昌範

ja 砂川, 昌範

花城, 和彦

× 花城, 和彦

ja 花城, 和彦

金城, 紀代彦

× 金城, 紀代彦

ja 金城, 紀代彦

中村, 真理子

× 中村, 真理子

ja 中村, 真理子

Kosugi, Tadayoshi

× Kosugi, Tadayoshi

en Kosugi, Tadayoshi

Sunagawa, Masanori

× Sunagawa, Masanori

en Sunagawa, Masanori

Hanashiro, Kazuhiko

× Hanashiro, Kazuhiko

en Hanashiro, Kazuhiko

Kinjoh, Kiyohiko

× Kinjoh, Kiyohiko

en Kinjoh, Kiyohiko

Nakamura, Mariko

× Nakamura, Mariko

en Nakamura, Mariko

アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利情報
言語 ja
権利情報 琉球医学会
主題
言語 en
主題Scheme Other
主題 interstitial collagenase
言語 en
主題Scheme Other
主題 type IV collagenase
言語 en
主題Scheme Other
主題 collagenase inhibitor
言語 en
主題Scheme Other
主題 tissue inhibitor of metalloproteinase 1
言語 en
主題Scheme Other
主題 procollagenase
内容記述
内容記述タイプ Other
内容記述 Extracellular matrix of the ovary during ovulation is degraded and remodelled. After ovulation, angiogenesis and repair occur in the ovary. The dynamic change of extracellular matrix during ovulation is based on the role of proteolytic enzymes. Besides the fibnnolytic enzymes, the enzymes of collagenolytic system play important role in ovulation. In this article, we report that interstitial collagenase, type IV collagenase, collagenase inhibitor, tissue inhibitor of metalloproteinase 1 (TIMP-1) which belong to collagenolytic system play important role in the rupture of follicle, the migration of oocyte and the expulsion of oocyte from the ovary. During gonadotropin-induced ovulation, at 3 hr to 6 hr after hCG administration the interstitial collagenase mRNA increased, but at 9 hr after hCG administration TIMP-I mRNA and collagenase type IV mRNA increased in the granulosa cell, thecal compartment and stroma compartment. Both the interstitial collagenase and type IV collagenase were secreted in the latent form (procollagenase). This latent form, procollagenase was activated by fibrinolytic enzyme, plasmin and converted to active collagenase. It was clarified that the cross talk of fibrinolytic enzymes and collagenolytic enzyme has been observed in the process of ovulation.
内容記述タイプ Other
内容記述 論文
出版者
言語 ja
出版者 琉球医学会
言語
言語 jpn
資源タイプ
資源タイプ journal article
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 1346888X
収録物識別子タイプ ISSN
収録物識別子 0289-1530
収録物識別子タイプ NCID
収録物識別子 AN10369445
収録物名
言語 ja
収録物名 琉球医学会誌 = Ryukyu Medical Journal
書誌情報
巻 18, 号 1-2, p. 11-14, 発行日 1998
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