| Item type |
デフォルトアイテムタイプ（フル）(1) |
| 公開日 |
2010-07-02 |
| タイトル |
|
|
タイトル |
[原著］蛇唆症の血液学的研究 : 第二報 DIC様脱線維素現象を示した中国南部地域の蛇唆症 |
|
言語 |
ja |
| タイトル |
|
|
タイトル |
Hematological Studies on the Snakebites : II. DIC-like Defibrinogenation on Patients with Snakebites in South China |
|
言語 |
en |
| 作成者 |
李, 其斌
黄, 光武
金城, 紀代彦
中村, 真理子
小杉, 忠誠
Lil, Qi-Bin
Huang, Guang-Wu
Kinjoh, Kiyohiko
Nakamura, Mariko
Kosugi, Tadayoshi
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利情報 |
|
|
言語 |
ja |
|
権利情報 |
琉球医学会 |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Snakebite |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
hemostatic disturbance |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
defibrinogenation |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
DIC-like syndrome |
| 内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
To characterize the hemostatic disturbances after snakebite, we measured the antithrombin III (AT-III) activity, $ \alpha $_2-plasmin inhibitor ($ \alpha $_2-PI) activity, fibrinogen concentration (Fg) and fibrin degradation products (FDP) in 21 patients envenomed by several snakes in south China from August 1998 to October 1999. The hematological changes obtained were as follows: the mean activity of AT-III was decreased in patients bitten by Ophiophagus hannah (Oh.), Bungarus fasciatus (Bf.), Hydrophis cyanocinctus (Hc.), Rhabdophis subminiatus (Rs.), Trimeresurus stejnegeri (Ts.), the mean activity of $ \alpha $_2-PI was also decreased in all patients in the present study; Fg was not detectable in Rs. bite, while Fg concentration in Ts., Oh., He. and Bf. bites markedly decreased. The mean levels of FDP were therefore increased in all patients. Thus, it appears that DIC-like syndrome would be seen in patients envenomed by snakebites. In this study, we found that the patients who were bitten by Rs. which is still being classified as a non-venomous snake showed complete defibrinogenation syndrome with severe hemorrhage without any evidence of severe multiple organ damage. We also found that the patients of Ts. bite showed marked hemostatic disturbance without severe multiple organ damage as well as Rs. bite. It is thought that a discrepancy between hematological findings and clinical symptoms may be a characteristic phenomenon of DIC-like syndrome caused by snakebites, especially by Rs. and Ts. bite. |
| 内容記述 |
|
|
内容記述タイプ |
Other |
|
内容記述 |
論文 |
| 出版者 |
|
|
出版者 |
琉球医学会 |
|
言語 |
ja |
| 出版者 |
|
|
出版者 |
Ryukyu Medical Association |
|
言語 |
en |
| 言語 |
|
|
言語 |
jpn |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
1346888X |
| 収録物識別子 |
|
|
収録物識別子タイプ |
ISSN |
|
収録物識別子 |
0289-1530 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AN10369445 |
| 収録物名 |
|
|
収録物名 |
琉球医学会誌 = Ryukyu Medical Journal |
|
言語 |
ja |
| 書誌情報 |
巻 20,
号 1,
p. 15-20
|
v20p15.pdf
