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[総説]臨床膵島移植と細胞処理センター
http://hdl.handle.net/20.500.12000/0002016874
http://hdl.handle.net/20.500.12000/0002016874db13cc72-d4a7-4682-8611-9c9f96b2af64
名前 / ファイル | ライセンス | アクション |
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v34p9.pdf
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Item type | デフォルトアイテムタイプ(フル)(1) | |||||||||
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公開日 | 2017-08-01 | |||||||||
タイトル | ||||||||||
タイトル | [総説]臨床膵島移植と細胞処理センター | |||||||||
言語 | ja | |||||||||
タイトル | ||||||||||
タイトル | [Review]Clinical islet transplantation and cell processing center | |||||||||
言語 | en | |||||||||
作成者 |
野口, 洋文
× 野口, 洋文
× Noguchi, Hirofumi
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アクセス権 | ||||||||||
アクセス権 | open access | |||||||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||
権利情報 | ||||||||||
言語 | ja | |||||||||
権利情報 | 琉球医学会 | |||||||||
主題 | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | islet transplantation | |||||||||
主題 | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | islet isolation | |||||||||
主題 | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | cell processing center (CPC) | |||||||||
主題 | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | current Good Manufacturing Practice (cGMP) | |||||||||
内容記述 | ||||||||||
内容記述タイプ | Other | |||||||||
内容記述 | Type 1 diabetes mellitus is an autoimmune disease characterized by the destruction of the islets of Langerhans cells, which produce insulin. Pancreatic islet transplantation is a promising option for the treatment of patients with type 1 diabetes who experience hypoglycemic unawareness despite receiving maximal care. Following the successful demonstration of the Edmonton protocol, more than 1,000 patients with type 1 diabetes have been treated at more than 50 institutions using islet transplantation. Clinical islet isolation is currently performed in a Good Manufacturing Practice (cGMP) islet processing facility, called a Cell Processing Center (CPC). The protocol for islet isolation has shown significant advancements on several fronts, including pancreatic ductal protection, improvements in pancreas preservation systems, a new islet purification method and culture/preservation of isolated islets. In this article, we review the current state of research regarding pancreatic islet transplantation. | |||||||||
内容記述 | ||||||||||
内容記述タイプ | Other | |||||||||
内容記述 | 論文 | |||||||||
出版者 | ||||||||||
言語 | ja | |||||||||
出版者 | 琉球医学会 | |||||||||
言語 | ||||||||||
言語 | jpn | |||||||||
資源タイプ | ||||||||||
資源タイプ | journal article | |||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
出版タイプ | ||||||||||
出版タイプ | VoR | |||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||
収録物識別子 | ||||||||||
収録物識別子タイプ | NCID | |||||||||
収録物識別子 | AN10369445 | |||||||||
収録物名 | ||||||||||
言語 | ja | |||||||||
収録物名 | 琉球医学会誌 = Ryukyu Medical Journal | |||||||||
書誌情報 |
巻 34, 号 1・2, p. 9-12 |