{"_buckets": {"deposit": "2befa460-593b-40fb-a0e0-1756849ff3a2"}, "_deposit": {"id": "2016889", "owners": [1], "pid": {"revision_id": 0, "type": "depid", "value": "2016889"}, "status": "published"}, "_oai": {"id": "oai:u-ryukyu.repo.nii.ac.jp:02016889", "sets": ["1642838231050", "1642838412624"]}, "author_link": [], "item_1617186331708": {"attribute_name": "Title", "attribute_value_mlt": [{"subitem_1551255647225": "\u6162\u6027\u814e\u81d3\u75c5\u306e\u75c5\u614b\u306b\u57fa\u3065\u3044\u305f\u500b\u5225\u5316\u6cbb\u7642\u306e\u5b9f\u8df5\u3068\u4eca\u5f8c\u306e\u5c55\u958b", "subitem_1551255648112": "ja"}, {"subitem_1551255647225": "Optimized therapy for chronic kidney disease based on individual pathogenesis and future directions", "subitem_1551255648112": "en"}]}, "item_1617186419668": {"attribute_name": "Creator", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "\u53e4\u6ce2\u8535, \u5065\u592a\u90ce", "creatorNameLang": "ja"}]}, {"creatorNames": [{"creatorName": "Kohagura, Kentaro", "creatorNameLang": "en"}]}]}, "item_1617186476635": {"attribute_name": "Access Rights", "attribute_value_mlt": [{"subitem_1522299639480": "open access", "subitem_1600958577026": "http://purl.org/coar/access_right/c_abf2"}]}, "item_1617186499011": {"attribute_name": "Rights", "attribute_value_mlt": [{"subitem_1522650717957": "ja", "subitem_1522651041219": "\u7409\u7403\u533b\u5b66\u4f1a"}]}, "item_1617186609386": {"attribute_name": "Subject", "attribute_value_mlt": [{"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "chronic kidney disease"}, {"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "glomerular hemodynamics"}, {"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "optimized therapy"}]}, "item_1617186626617": {"attribute_name": "Description", "attribute_value_mlt": [{"subitem_description": "Chronic kidney disease (CKD) is a major public health issue worldwide. Secondary changes in glomerular hemodynamics accelerate the progression of CKD. Afferent arterioles have a pivotal role in the regulation of glomerular hemodynamics. We conducted some experimental studies to examine the mechanisms underlying the regulation of afferent arteriolar tone using a micro perfusion technique. Furthermore, we tried to evaluate changes in glomerular hemodynamics by observing morphological changes in afferent arterioles and glomeruli using specimen of renal biopsy. We achieved great success in the treatment of CKD by applying such morphological evaluation for the optimization of personal treatment strategies. Furthermore, we published some clinical and experimental papers regarding renal arteriolopathy, which focused on the pathogenesis of cardiorenal connection as well as the progression of CKD. In the near future, we plan to establish a framework for an optimized therapy of CKD based on individual pathogenesis and regional medical network system in Okinawa, Japan.", "subitem_description_type": "Other"}, {"subitem_description": "\u8ad6\u6587", "subitem_description_type": "Other"}]}, "item_1617186643794": {"attribute_name": "Publisher", "attribute_value_mlt": [{"subitem_1522300295150": "ja", "subitem_1522300316516": "\u7409\u7403\u533b\u5b66\u4f1a"}, {"subitem_1522300295150": "en", "subitem_1522300316516": "Ryukyu Medical Association"}]}, "item_1617186702042": {"attribute_name": "Language", "attribute_value_mlt": [{"subitem_1551255818386": "jpn"}]}, "item_1617186920753": {"attribute_name": "Source Identifier", "attribute_value_mlt": [{"subitem_1522646500366": "ISSN", "subitem_1522646572813": "1346-888X"}, {"subitem_1522646500366": "NCID", "subitem_1522646572813": "AN10369445"}]}, "item_1617186941041": {"attribute_name": "Source Title", "attribute_value_mlt": [{"subitem_1522650068558": "ja", "subitem_1522650091861": "\u7409\u7403\u533b\u5b66\u4f1a\u8a8c = Ryukyu Medical Journal"}]}, "item_1617187056579": {"attribute_name": "Bibliographic Information", "attribute_value_mlt": [{"bibliographicIssueNumber": "1-2", "bibliographicPageEnd": "7", "bibliographicPageStart": "1", "bibliographicVolumeNumber": "36"}]}, "item_1617258105262": {"attribute_name": "Resource Type", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_1617265215918": {"attribute_name": "Version Type", "attribute_value_mlt": [{"subitem_1522305645492": "VoR", "subitem_1600292170262": "http://purl.org/coar/version/c_970fb48d4fbd8a85"}]}, "item_1617605131499": {"attribute_name": "File", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_access", "download_preview_message": "", "file_order": 0, "filename": "v36(1-2)p1.pdf", "future_date_message": "", "is_thumbnail": false, "mimetype": "", "size": 0, "url": {"objectType": "fulltext", "url": "https://u-ryukyu.repo.nii.ac.jp/record/2016889/files/v36(1-2)p1.pdf"}, "version_id": "7d84ad2a-5221-4bb6-a37f-27cd930744fc"}]}, "item_title": "\u6162\u6027\u814e\u81d3\u75c5\u306e\u75c5\u614b\u306b\u57fa\u3065\u3044\u305f\u500b\u5225\u5316\u6cbb\u7642\u306e\u5b9f\u8df5\u3068\u4eca\u5f8c\u306e\u5c55\u958b", "item_type_id": "15", "owner": "1", "path": ["1642838231050", "1642838412624"], "permalink_uri": "http://hdl.handle.net/20.500.12000/0002016889", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2018-12-26"}, "publish_date": "2018-12-26", "publish_status": "0", "recid": "2016889", "relation": {}, "relation_version_is_last": true, "title": ["\u6162\u6027\u814e\u81d3\u75c5\u306e\u75c5\u614b\u306b\u57fa\u3065\u3044\u305f\u500b\u5225\u5316\u6cbb\u7642\u306e\u5b9f\u8df5\u3068\u4eca\u5f8c\u306e\u5c55\u958b"], "weko_shared_id": -1}