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慢性腎臓病の病態に基づいた個別化治療の実践と今後の展開
http://hdl.handle.net/20.500.12000/0002016889
http://hdl.handle.net/20.500.12000/0002016889174fe92e-27e5-4131-bcea-0780bdf5a6bf
名前 / ファイル | ライセンス | アクション |
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v36(1-2)p1.pdf
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Item type | デフォルトアイテムタイプ(フル)(1) | |||||||||
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公開日 | 2018-12-26 | |||||||||
タイトル | ||||||||||
タイトル | 慢性腎臓病の病態に基づいた個別化治療の実践と今後の展開 | |||||||||
言語 | ja | |||||||||
タイトル | ||||||||||
タイトル | Optimized therapy for chronic kidney disease based on individual pathogenesis and future directions | |||||||||
言語 | en | |||||||||
作成者 |
古波蔵, 健太郎
× 古波蔵, 健太郎
× Kohagura, Kentaro
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アクセス権 | ||||||||||
アクセス権 | open access | |||||||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||
権利情報 | ||||||||||
言語 | ja | |||||||||
権利情報 | 琉球医学会 | |||||||||
主題 | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | chronic kidney disease | |||||||||
主題 | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | glomerular hemodynamics | |||||||||
主題 | ||||||||||
言語 | en | |||||||||
主題Scheme | Other | |||||||||
主題 | optimized therapy | |||||||||
内容記述 | ||||||||||
内容記述タイプ | Other | |||||||||
内容記述 | Chronic kidney disease (CKD) is a major public health issue worldwide. Secondary changes in glomerular hemodynamics accelerate the progression of CKD. Afferent arterioles have a pivotal role in the regulation of glomerular hemodynamics. We conducted some experimental studies to examine the mechanisms underlying the regulation of afferent arteriolar tone using a micro perfusion technique. Furthermore, we tried to evaluate changes in glomerular hemodynamics by observing morphological changes in afferent arterioles and glomeruli using specimen of renal biopsy. We achieved great success in the treatment of CKD by applying such morphological evaluation for the optimization of personal treatment strategies. Furthermore, we published some clinical and experimental papers regarding renal arteriolopathy, which focused on the pathogenesis of cardiorenal connection as well as the progression of CKD. In the near future, we plan to establish a framework for an optimized therapy of CKD based on individual pathogenesis and regional medical network system in Okinawa, Japan. | |||||||||
内容記述 | ||||||||||
内容記述タイプ | Other | |||||||||
内容記述 | 論文 | |||||||||
出版者 | ||||||||||
言語 | ja | |||||||||
出版者 | 琉球医学会 | |||||||||
出版者 | ||||||||||
言語 | en | |||||||||
出版者 | Ryukyu Medical Association | |||||||||
言語 | ||||||||||
言語 | jpn | |||||||||
資源タイプ | ||||||||||
資源タイプ | journal article | |||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||
出版タイプ | ||||||||||
出版タイプ | VoR | |||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||
収録物識別子 | ||||||||||
収録物識別子タイプ | ISSN | |||||||||
収録物識別子 | 1346-888X | |||||||||
収録物識別子 | ||||||||||
収録物識別子タイプ | NCID | |||||||||
収録物識別子 | AN10369445 | |||||||||
収録物名 | ||||||||||
言語 | ja | |||||||||
収録物名 | 琉球医学会誌 = Ryukyu Medical Journal | |||||||||
書誌情報 |
巻 36, 号 1-2, p. 1-7 |