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Psychopathology and clinical outcomes of first-visit outpatients under 20 years old exhibiting a psychotic state
http://hdl.handle.net/20.500.12000/0002016921
http://hdl.handle.net/20.500.12000/0002016921192d6b62-d8f9-4ab5-810a-c70f1a2c32d1
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
Vol39p29.pdf
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| Item type | デフォルトアイテムタイプ（フル）(1) | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2021-11-18 | |||||||||||||||
| タイトル | ||||||||||||||||
| タイトル | Psychopathology and clinical outcomes of first-visit outpatients under 20 years old exhibiting a psychotic state | |||||||||||||||
| 言語 | en | |||||||||||||||
| 作成者 |
Ishibashi, Takao
× Ishibashi, Takao
× Shinzato, Hotaka
× Zamami, Yu
× Shimabukuro, Morihiro
× Kondo, Tsuyoshi
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| アクセス権 | ||||||||||||||||
| アクセス権 | open access | |||||||||||||||
| アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||||||||||||
| 権利情報 | ||||||||||||||||
| 言語 | ja | |||||||||||||||
| 権利情報 | 琉球医学会 | |||||||||||||||
| 主題 | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | under 20 | |||||||||||||||
| 主題 | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | schizophrenia | |||||||||||||||
| 主題 | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | at risk mental state | |||||||||||||||
| 主題 | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | early symptoms | |||||||||||||||
| 主題 | ||||||||||||||||
| 言語 | en | |||||||||||||||
| 主題Scheme | Other | |||||||||||||||
| 主題 | insight | |||||||||||||||
| 内容記述 | ||||||||||||||||
| 内容記述タイプ | Other | |||||||||||||||
| 内容記述 | outcome of patients under 20 years old exhibiting a psychotic state. Methods: Forty-five patients (15 males and 30 females) under 20 years old with a diagnostic description of psychosis, schizophrenia, at-risk mental state (ARMS) or psychotic-like experiences, who had first visited our clinic between January 2012 and December 2017 were retrospectively extracted from medical records. Their age at the onset of symptoms; psychiatric diagnoses, including comorbidities; insight of disease; symptomatology (early, positive, negative, catatonic and anxiety-depression symptoms); course of illness; prescribed medication; and final treatment outcome were investigated from various aspects. Results: Prodromal stages of schizophrenia (ARMS and early schizophrenia) were observed in about one-third of the overall patients. Patients with insight of disease had a higher baseline global assessment of functioning and greater number of early schizophrenic symptoms and anxiety-depression symptoms than those without insight of disease. In particular, early schizophrenic symptoms appear to be a discriminating factor for insight of disease. A total of 36.4% of ARMS patients converted to schizophrenia, while 25% of early schizophrenia patients converted to frank schizophrenia. Doses of antipsychotics (chlorpromazine equivalence: mg/day) were lower in ARMS non-converters (100±63) than in ARMS converters (364±44) or schizophrenics (477±337). Among overall patients, 62.3% showed improvement as the final treatment outcome. The global assessment of functioning values were higher at 6 (54.2%±17.2%) and 12 months (55.1%±18.9%) than that at baseline (34.1%±10.3%). Conclusion: The present study suggests that clinicians need to actively ask about early symptoms or attenuated positive symptoms in patients under 20 years old with a psychotic state who may still have insight of disease and encourage voluntary help-seeking. The first six months might be a critical period for achieving symptomatological remission and functional recovery in these patients. | |||||||||||||||
| 内容記述 | ||||||||||||||||
| 内容記述タイプ | Other | |||||||||||||||
| 内容記述 | 論文 | |||||||||||||||
| 出版者 | ||||||||||||||||
| 出版者 | 琉球医学会 | |||||||||||||||
| 言語 | ja | |||||||||||||||
| 出版者 | ||||||||||||||||
| 出版者 | Ryukyu Medical Association | |||||||||||||||
| 言語 | en | |||||||||||||||
| 言語 | ||||||||||||||||
| 言語 | eng | |||||||||||||||
| 資源タイプ | ||||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||
| 資源タイプ | journal article | |||||||||||||||
| 出版タイプ | ||||||||||||||||
| 出版タイプ | VoR | |||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||||
| 収録物識別子 | ||||||||||||||||
| 収録物識別子タイプ | ISSN | |||||||||||||||
| 収録物識別子 | 1346-888X | |||||||||||||||
| 収録物識別子 | ||||||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||||||
| 収録物識別子 | AN10369445 | |||||||||||||||
| 収録物名 | ||||||||||||||||
| 収録物名 | 琉球医学会誌 = Ryukyu Medical Journal | |||||||||||||||
| 言語 | ja | |||||||||||||||
| 書誌情報 |
巻 39, 号 1-4, p. 29-40 |
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Cite as
Ishibashi, Takao, Shinzato, Hotaka, Zamami, Yu, Shimabukuro, Morihiro, Kondo, Tsuyoshi, n.d., Psychopathology and clinical outcomes of first-visit outpatients under 20 years old exhibiting a psychotic state: 琉球医学会.
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