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  1. 学術雑誌論文
  2. 琉球医学会
  3. 琉球医学会誌
  4. 39巻1-4号
  1. 部局別インデックス
  2. その他

Psychopathology and clinical outcomes of first-visit outpatients under 20 years old exhibiting a psychotic state

http://hdl.handle.net/20.500.12000/0002016921
http://hdl.handle.net/20.500.12000/0002016921
192d6b62-d8f9-4ab5-810a-c70f1a2c32d1
名前 / ファイル ライセンス アクション
Vol39p29.pdf Vol39p29.pdf
Item type デフォルトアイテムタイプ(フル)(1)
公開日 2021-11-18
タイトル
タイトル Psychopathology and clinical outcomes of first-visit outpatients under 20 years old exhibiting a psychotic state
言語 en
作成者 Ishibashi, Takao

× Ishibashi, Takao

en Ishibashi, Takao

Shinzato, Hotaka

× Shinzato, Hotaka

en Shinzato, Hotaka

Zamami, Yu

× Zamami, Yu

en Zamami, Yu

Shimabukuro, Morihiro

× Shimabukuro, Morihiro

en Shimabukuro, Morihiro

Kondo, Tsuyoshi

× Kondo, Tsuyoshi

en Kondo, Tsuyoshi

アクセス権
アクセス権 open access
アクセス権URI http://purl.org/coar/access_right/c_abf2
権利情報
言語 ja
権利情報 琉球医学会
主題
言語 en
主題Scheme Other
主題 under 20
言語 en
主題Scheme Other
主題 schizophrenia
言語 en
主題Scheme Other
主題 at risk mental state
言語 en
主題Scheme Other
主題 early symptoms
言語 en
主題Scheme Other
主題 insight
内容記述
内容記述タイプ Other
内容記述 outcome of patients under 20 years old exhibiting a psychotic state. Methods: Forty-five patients (15 males and 30 females) under 20 years old with a diagnostic description of psychosis, schizophrenia, at-risk mental state (ARMS) or psychotic-like experiences, who had first visited our clinic between January 2012 and December 2017 were retrospectively extracted from medical records. Their age at the onset of symptoms; psychiatric diagnoses, including comorbidities; insight of disease; symptomatology (early, positive, negative, catatonic and anxiety-depression symptoms); course of illness; prescribed medication; and final treatment outcome were investigated from various aspects. Results: Prodromal stages of schizophrenia (ARMS and early schizophrenia) were observed in about one-third of the overall patients. Patients with insight of disease had a higher baseline global assessment of functioning and greater number of early schizophrenic symptoms and anxiety-depression symptoms than those without insight of disease. In particular, early schizophrenic symptoms appear to be a discriminating factor for insight of disease. A total of 36.4% of ARMS patients converted to schizophrenia, while 25% of early schizophrenia patients converted to frank schizophrenia. Doses of antipsychotics (chlorpromazine equivalence: mg/day) were lower in ARMS non-converters (100±63) than in ARMS converters (364±44) or schizophrenics (477±337). Among overall patients, 62.3% showed improvement as the final treatment outcome. The global assessment of functioning values were higher at 6 (54.2%±17.2%) and 12 months (55.1%±18.9%) than that at baseline (34.1%±10.3%). Conclusion: The present study suggests that clinicians need to actively ask about early symptoms or attenuated positive symptoms in patients under 20 years old with a psychotic state who may still have insight of disease and encourage voluntary help-seeking. The first six months might be a critical period for achieving symptomatological remission and functional recovery in these patients.
内容記述タイプ Other
内容記述 論文
出版者
言語 ja
出版者 琉球医学会
言語
言語 eng
資源タイプ
資源タイプ journal article
資源タイプ識別子 http://purl.org/coar/resource_type/c_6501
出版タイプ
出版タイプ VoR
出版タイプResource http://purl.org/coar/version/c_970fb48d4fbd8a85
収録物識別子
収録物識別子タイプ ISSN
収録物識別子 1346-888X
収録物識別子タイプ NCID
収録物識別子 AN10369445
収録物名
言語 ja
収録物名 琉球医学会誌 = Ryukyu Medical Journal
書誌情報
巻 39, 号 1-4, p. 29-40
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