| Item type |
琉球大学リポジトリ登録用アイテムタイプ(1) |
| 公開日 |
2024-10-08 |
| タイトル |
|
|
タイトル |
The correlation between HTLV-1 and Whipple's disease in a Japanese population: A case series |
|
言語 |
en |
| 作成者 |
Furugen, Tomonori
| en |
Furugen, Tomonori
Graduate school of Medicine, University of the Ryukyus
|
| ja |
琉球大学大学院医学研究科
|
Search repository
Kinjo, Tetsu
Hokama, Akira
Furukawa, Kojiro
| en |
Furukawa, Kojiro
Graduate school of Medicine, University of the Ryukyus
|
| ja |
琉球大学大学院医学研究科
|
Search repository
Karube, Kennosuke
| en |
Karube, Kennosuke
Graduate School of Medicine, Nagoya University
|
| ja |
名古屋大学大学院医学系研究科
|
Search repository
|
| アクセス権 |
|
|
アクセス権 |
open access |
|
アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 権利情報 |
|
|
言語 |
ja |
|
権利情報 |
琉球医学会 |
| 権利情報 |
|
|
言語 |
en |
|
権利情報 |
Ryukyu Medical Association |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
Whippleʼs disease |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
HTLV-1 |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
immunosuppression |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
proviral load |
| 主題 |
|
|
言語 |
en |
|
主題Scheme |
Other |
|
主題 |
adult T-cell leukemia / lymphoma |
| 内容記述 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Purpose: Whippleʼs disease (WD) is a rare systemic disease caused by Tropheryma whipplei. It is predominantly diagnosed in middle-aged Caucasian men, and its association with immunosuppression and human leukocyte antigen (HLA)-B27 has been discussed; however, these studies are limited to western countries. Herein, we analyzed five WD cases and eight previously described WD cases in the Japanese population.
Results: None of the patients were under immunosuppressive treatment or HLA-B27-positive. In 10/13 cases checking anti-HTLV-1 antibody, 6/10 (60%) cases were carriers of human T-cell leukemia virus type 1 (HTLV-1). All patients were treated with antibiotics, and their symptoms diminished promptly. The prognosis for these cases was excellent, and one patient developed the smoldering type adult T-cell leukemia/lymphoma, but no progression to aggressive type adult T-cell leukemia/lymphoma was observed.
Conclusion: These findings probably support the findings that the immunosuppressive effect of HTLV-1 triggers WD in Japanese patients. It is recommended to evaluate the presence of HTLV-1 antibody in the blood of WD patients in HTLV-1 endemic areas for the clarification of the accurate pathogenesis and appropriate clinical follow-up. Ryukyu Med. J., 42 (1～4) 21～28, 2023 |
|
言語 |
en |
| 出版者 |
|
|
出版者 |
琉球医学会 |
|
言語 |
ja |
| 出版者 |
|
|
出版者 |
Ryukyu Medical Association |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 収録物識別子 |
|
|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
1346-888X |
| 収録物識別子 |
|
|
収録物識別子タイプ |
NCID |
|
収録物識別子 |
AN10369445 |
| 収録物名 |
|
|
収録物名 |
琉球医学会誌 = Ryukyu Medical Journal |
|
言語 |
ja |
| 書誌情報 |
巻 42,
号 1-4,
p. 21-28,
発行日 2023
|
F_No42p21.pdf (1.2 MB)
