{"_buckets": {"deposit": "64c1ebed-bf33-44a3-9c73-ba73fb109553"}, "_deposit": {"id": "2016083", "owners": [1], "pid": {"revision_id": 0, "type": "depid", "value": "2016083"}, "status": "published"}, "_oai": {"id": "oai:u-ryukyu.repo.nii.ac.jp:02016083", "sets": ["1642838211991", "1642838412624"]}, "author_link": [], "item_1617186331708": {"attribute_name": "Title", "attribute_value_mlt": [{"subitem_1551255647225": "[\u539f\u8457\uff3dIn-situ perfusion of the liver as a stable model of cold ischemia in orthotopic liver transplantation", "subitem_1551255648112": "ja"}]}, "item_1617186419668": {"attribute_name": "Creator", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Shiraishi, Masayuki", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Nozato, Eiji", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Okuhama, Yukihiro", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Tomori, Hirofumi", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Higa, Takao", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Taira, Kaoru", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Muto, Yoshihiro", "creatorNameLang": "en"}]}]}, "item_1617186476635": {"attribute_name": "Access Rights", "attribute_value_mlt": [{"subitem_1522299639480": "open access", "subitem_1600958577026": "http://purl.org/coar/access_right/c_abf2"}]}, "item_1617186499011": {"attribute_name": "Rights", "attribute_value_mlt": [{"subitem_1522650717957": "ja", "subitem_1522651041219": "\u7409\u7403\u533b\u5b66\u4f1a"}]}, "item_1617186609386": {"attribute_name": "Subject", "attribute_value_mlt": [{"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "ischemia reperfusion injury"}, {"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "liver"}, {"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "in-situ per fusion"}]}, "item_1617186626617": {"attribute_name": "Description", "attribute_value_mlt": [{"subitem_description": "Various models of hepatic ischemia/reperfusion (I/R) injury were tested, using both rats (groups 1, 2 and 3, each n=10) and pigs (groups4 and5, each n=5). To create cold ischemia for 1 hr, an orthotopic liver transplantation (OLT) was performed in groups 1 and 4 using the cuff technique to reconstruct the portal vein and infra-hepatic vein in group 1, and using the veno-venous bypass during a non-hepatic phase in group 4. In groups 3 and 5, in-situ perfusion of the liver was performed without taking out the liver under a portosystemic shunt, which was achieved by a splenic transposition (created 4 weeks prior to the surgery) in group 3, and by a pump controlled veno-venous bypass in group 5. In group 2, a simple clamp of the portal triads was applied, without flushing out the blood from the liver. The survival rate at 1 week after surgery was 90% (9/10), 70% (7/10), 100% (10/10), 60% (3/5), 100% (5/5) in groups 1 to 5, respectively. Regarding the macroscopic findings of the liver 1 week after ischemia, lobar necrosis (1 case) and patchy necrosis (3 case) were characteristically found in group 1, but not in either groups 2 or 3. The serum hepatic enzyme levels showed a large deviation from case to case in groups 1, 2, and 4, in response to the same amount of cold ischemia. However, these values were relatively uniform in groups 3 and 5, in which in-situ per fusion was performed. In conclusion, the above described in-situ perfusion model of the liver is thus considered to provide a stable in-vivo model for studying hepatic I/R injury, in both rats and pigs.", "subitem_description_type": "Other"}, {"subitem_description": "\u8ad6\u6587", "subitem_description_type": "Other"}]}, "item_1617186643794": {"attribute_name": "Publisher", "attribute_value_mlt": [{"subitem_1522300295150": "ja", "subitem_1522300316516": "\u7409\u7403\u533b\u5b66\u4f1a"}, {"subitem_1522300295150": "en", "subitem_1522300316516": "Ryukyu Medical Association"}]}, "item_1617186702042": {"attribute_name": "Language", "attribute_value_mlt": [{"subitem_1551255818386": "eng"}]}, "item_1617186920753": {"attribute_name": "Source Identifier", "attribute_value_mlt": [{"subitem_1522646500366": "ISSN", "subitem_1522646572813": "1346888X"}, {"subitem_1522646500366": "ISSN", "subitem_1522646572813": "0289-1530"}, {"subitem_1522646500366": "NCID", "subitem_1522646572813": "AN10369445"}]}, "item_1617186941041": {"attribute_name": "Source Title", "attribute_value_mlt": [{"subitem_1522650068558": "ja", "subitem_1522650091861": "\u7409\u7403\u533b\u5b66\u4f1a\u8a8c = Ryukyu Medical Journal"}]}, "item_1617187056579": {"attribute_name": "Bibliographic Information", "attribute_value_mlt": [{"bibliographicIssueNumber": "3", "bibliographicPageEnd": "77", "bibliographicPageStart": "73", "bibliographicVolumeNumber": "18"}]}, "item_1617258105262": {"attribute_name": "Resource Type", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_1617265215918": {"attribute_name": "Version Type", "attribute_value_mlt": [{"subitem_1522305645492": "VoR", "subitem_1600292170262": "http://purl.org/coar/version/c_970fb48d4fbd8a85"}]}, "item_1617605131499": {"attribute_name": "File", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_access", "download_preview_message": "", "file_order": 0, "filename": "v18p73.pdf", "future_date_message": "", "is_thumbnail": false, "mimetype": "", "size": 0, "url": {"objectType": "fulltext", "url": "https://u-ryukyu.repo.nii.ac.jp/record/2016083/files/v18p73.pdf"}, "version_id": "16f850ad-de36-4f10-ab23-0a38cca2db85"}]}, "item_title": "[\u539f\u8457\uff3dIn-situ perfusion of the liver as a stable model of cold ischemia in orthotopic liver transplantation", "item_type_id": "15", "owner": "1", "path": ["1642838211991", "1642838412624"], "permalink_uri": "http://hdl.handle.net/20.500.12000/0002016083", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2010-07-02"}, "publish_date": "2010-07-02", "publish_status": "0", "recid": "2016083", "relation": {}, "relation_version_is_last": true, "title": ["[\u539f\u8457\uff3dIn-situ perfusion of the liver as a stable model of cold ischemia in orthotopic liver transplantation"], "weko_shared_id": -1}