{"_buckets": {"deposit": "49d32c2a-e6cb-466f-86dd-963e82a53c7f"}, "_deposit": {"id": "2015850", "owners": [1], "pid": {"revision_id": 0, "type": "depid", "value": "2015850"}, "status": "published"}, "_oai": {"id": "oai:u-ryukyu.repo.nii.ac.jp:02015850", "sets": ["1642838201426", "1642838412624"]}, "author_link": [], "item_1617186331708": {"attribute_name": "Title", "attribute_value_mlt": [{"subitem_1551255647225": "[\u539f\u8457\uff3dA Histochemical Comparative Study on Four Different Types of Lectins and Carcinoembryonic Antigen (CEA) on Human Colorectal Tissues", "subitem_1551255648112": "ja"}]}, "item_1617186419668": {"attribute_name": "Creator", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Faisal, Muazzam A", "creatorNameLang": "en"}]}, {"creatorNames": [{"creatorName": "Yoshihiro, Muto", "creatorNameLang": "en"}]}]}, "item_1617186476635": {"attribute_name": "Access Rights", "attribute_value_mlt": [{"subitem_1522299639480": "open access", "subitem_1600958577026": "http://purl.org/coar/access_right/c_abf2"}]}, "item_1617186499011": {"attribute_name": "Rights", "attribute_value_mlt": [{"subitem_1522650717957": "ja", "subitem_1522651041219": "\u7409\u7403\u533b\u5b66\u4f1a"}]}, "item_1617186609386": {"attribute_name": "Subject", "attribute_value_mlt": [{"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "colon and rectum"}, {"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "neoplastic lesion"}, {"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "adjacent non-neoplastic mucosa"}, {"subitem_1522299896455": "en", "subitem_1522300014469": "Other", "subitem_1523261968819": "UEA-1 and CEA."}]}, "item_1617186626617": {"attribute_name": "Description", "attribute_value_mlt": [{"subitem_description": "To evaluate the specificity and efficacy of lectin histochemical staining characteristics on human colorectal neoplastic and adjacent non-neoplastic tissue, a thorough comparative study has been performed to that of a recognized colorectal tumor marker,carcinoembryonic antigen (CEA). Neoplastic tissue and adjacent non-neoplastic mucosa of 26 surgically extirpated specimens were examined lectin histochemically by four differentlectins (Ulex europaeus-I. Arachis hypogaea, Triticum vulgare and Canavaha ensiformis) and immunohistochemically by anti CEA antibody. According to their degree of staining all the four lectins(UEA-I moderate 57.69%, extensive 39.42%; PNA moderate 60.57% extensive 5.76%; WGA moderate 76.92% extensive 1.92% and Con-A moderate 48.07%. extensive 51.29%) and CEA (moderate 66.34%,extensive 22.11%)showed very high percentages of positive staining for neoplastic tissues but almost reciprocal results were observed by UEA-I (moderate 7.69%, extensive O%) and partially by PNA lectin (moderate 15.38%,extensive O%) for non-neoplastic mucosa (P\u003c0.01). While CEA (moderate 50%, extensive 19.23%) and the other two lectins did not show much differences in their staining percentages for non-neoplastic mucosa (P\u003e0.05). Further study regarding their staining pattern revealed that for neoplastic tissues UEA-I mainly stained the cytoplasmic (without polarity) (60.58%) or the stromal (28.85%) types but in case of non-neoplastic mucosa the cytoplasmic (with polarity) (57.15%) or the apical (35.71%) types predominated. No such distinct staining patterens were observed for CEA and the other lectins. From our study it is strongly suggestive that UEA-I lectinis by far morespecific and localized for the malignant transformation of colorectal tissues with compared to that of carcinoembryonic antigen, CEA.", "subitem_description_type": "Other"}, {"subitem_description": "\u8ad6\u6587", "subitem_description_type": "Other"}]}, "item_1617186643794": {"attribute_name": "Publisher", "attribute_value_mlt": [{"subitem_1522300295150": "ja", "subitem_1522300316516": "\u7409\u7403\u533b\u5b66\u4f1a"}, {"subitem_1522300295150": "en", "subitem_1522300316516": "Ryukyu Medical Association"}]}, "item_1617186702042": {"attribute_name": "Language", "attribute_value_mlt": [{"subitem_1551255818386": "eng"}]}, "item_1617186920753": {"attribute_name": "Source Identifier", "attribute_value_mlt": [{"subitem_1522646500366": "ISSN", "subitem_1522646572813": "1346888X"}, {"subitem_1522646500366": "ISSN", "subitem_1522646572813": "0289-1530"}, {"subitem_1522646500366": "NCID", "subitem_1522646572813": "AN10369445"}]}, "item_1617186941041": {"attribute_name": "Source Title", "attribute_value_mlt": [{"subitem_1522650068558": "ja", "subitem_1522650091861": "\u7409\u7403\u533b\u5b66\u4f1a\u8a8c = Ryukyu Medical Journal"}]}, "item_1617187056579": {"attribute_name": "Bibliographic Information", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1992", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "4", "bibliographicPageEnd": "306", "bibliographicPageStart": "295", "bibliographicVolumeNumber": "12"}]}, "item_1617258105262": {"attribute_name": "Resource Type", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_1617265215918": {"attribute_name": "Version Type", "attribute_value_mlt": [{"subitem_1522305645492": "VoR", "subitem_1600292170262": "http://purl.org/coar/version/c_970fb48d4fbd8a85"}]}, "item_1617605131499": {"attribute_name": "File", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_access", "download_preview_message": "", "file_order": 0, "filename": "v12p295.pdf", "future_date_message": "", "is_thumbnail": false, "mimetype": "", "size": 0, "url": {"objectType": "fulltext", "url": "https://u-ryukyu.repo.nii.ac.jp/record/2015850/files/v12p295.pdf"}, "version_id": "7ece71d9-a7a5-40c2-94b4-445e2c96af28"}]}, "item_title": "[\u539f\u8457\uff3dA Histochemical Comparative Study on Four Different Types of Lectins and Carcinoembryonic Antigen (CEA) on Human Colorectal Tissues", "item_type_id": "15", "owner": "1", "path": ["1642838201426", "1642838412624"], "permalink_uri": "http://hdl.handle.net/20.500.12000/0002015850", "pubdate": {"attribute_name": "PubDate", "attribute_value": "2010-07-02"}, "publish_date": "2010-07-02", "publish_status": "0", "recid": "2015850", "relation": {}, "relation_version_is_last": true, "title": ["[\u539f\u8457\uff3dA Histochemical Comparative Study on Four Different Types of Lectins and Carcinoembryonic Antigen (CEA) on Human Colorectal Tissues"], "weko_shared_id": -1}